The police report showed that the 91-year-old man was listed as a suspect.

　　Recently, an 81-year-old couple and a 54-year-old son in Pizhou City, Jiangsu Province were listed as suspects in the anti-gang activities, and the local public security bureau also offered a reward of 1000 yuan to 10,000 yuan to collect clues about their involvement in the crime. This matter quickly fermented in the field of public opinion, and some netizens hotly debated that "this is probably the oldest ‘ Black ’ Personnel ".

　　The Public Security Bureau of Pizhou City responded quickly on July 19: two elderly sons were instructed by their sons to occupy the village collective houses for a long time without any reason, and the three repeatedly went to the police station to insult the police and block the investigation.

　　Procurator-General of the Supreme People’s Procuratorate: Every criminal is spared, and every criminal is not spared.

　　"It doesn’t mean that you won’t be suspected of committing a crime when you are older." The local police responded to the media like this. Although there is nothing wrong with the truth, "evil forces" is not a small charge, so we must be cautious when deducting it.

On July 18th, "Focus Interview" broadcast the program "Sweeping the evil and eliminating the evil".

　　On July 18th, "Focus Interview" broadcast the program "Sweeping the Black and Eliminating Evil", which discussed exactly how to judge and grasp the scale in the process of sweeping the black.

　　At the beginning of the program, three key terms were put forward: underworld, evil group and evil force. These are three types of crimes with decreasing severity, and the judgment standards and sentencing are also different.

　　The program cited a case to illustrate. In Fengcheng Reservoir, Zhenjiang City, Jiangsu Province, some people had a dispute over the right to operate the reservoir. On one side is the reservoir operator named Luming, and the name of the dispute with him is hao yang. Since 2010, hao yang has been hoping to get the right to operate the reservoir from Luming, so many people have been gathered from the society to harass.

　　In the most serious case, hao yang gathered several people to the scene with clubs to make a nuisance, and had a fight with several workers under Luming, injuring the workers and Luming. There were five cases that constituted illegal crimes, and they were convicted of crimes of suspected provocation and affray.

　　Hao yang gangs mainly obtain economic benefits through usury, and have repeatedly committed crimes. In order to collect usury, the debtor is often forced by soft violence such as threats and intimidation, and once he even illegally detained the other party in the guest room for four days.

　　In addition, some hao yang gang members also participated in the crime committed by the gang headed by Fang Yadong, forming another criminal group. After mastering a large amount of evidence, in April 2018, hao yang and Fang Yadong were listed as the first batch of triad-related cases in Jiangsu Province, and finally 36 illegal and criminal facts were determined.

　　Although the facts of the crime have been ascertained, both parties have different views on the qualitative and public prosecution of the case. The public security organs believe that this belongs to organized crime of underworld nature, while the procuratorial organs believe that it belongs to evil criminal groups. Because from the aspects of organization, economy and harmfulness, it is not enough for the standard of black-related.

　　After repeated investigation and communication, the procuratorate decided to prosecute according to "evil-related". Defendants hao yang and Fang Yadong were sentenced to five years’ imprisonment for the crime of affray, the crime of stirring up trouble, and the combined punishment of several crimes. However, if they are classified as "organized crimes of underworld nature", the sentencing will be heavier.

　　The case reported in Focus Interview comes from the Selected Typical Cases of Procuratorial Organs’ Special Struggle to Eliminate Evil (Series 3) recently issued by the Supreme People’s Procuratorate (hereinafter referred to as the Selected Works). This edition of Selected Works contains a total of five cases, all of which are selected according to Zhang Jun, Procurator-General of the Supreme People’s Procuratorate’s requirements of "not letting go of all black and evil crimes, but not making up all black and evil crimes", aiming at strictly following the principles of legality, judging evidence, excluding illegal evidence, procedural justice and so on, and standardizing handling cases according to law.

　　National Anti-triad Office: Minors, the elderly and the disabled should be especially careful when identifying evil forces.

　　While the iron is hot, you need to be hard. Since the launch of the "anti-vice" campaign, the National Anti-vice Office has repeatedly issued guidance opinions and material compilations to ensure that the special struggle against vice has always been promoted on the track of the rule of law, and to ensure the principle of "neither being degraded nor artificially inflated".

　　For example, on April 9 this year, the Supreme People’s Court, the Supreme People’s Procuratorate, the Ministry of Public Security and the Ministry of Justice jointly issued four opinions, namely, Opinions on Handling Criminal Cases of Evil Forces, Opinions on Handling Criminal Cases of Routine Loans, Opinions on Handling Property in Criminal Cases of Evil Forces, Opinions on Handling Criminal Cases of Soft Violence, and so on, which were released to the public and provided for severely punishing crimes committed by evil forces according to law.

　　Among them, the Opinions on Several Issues Concerning Handling Criminal Cases of Evil Forces clearly stipulates the identification standards, relevant requirements and specific implementation of handling criminal cases of evil forces.

　　The "Opinions" pointed out that to identify "evil forces", we should consider factors such as "more than three people, the participants are relatively fixed" and "often gathering together to commit illegal and criminal activities in a certain area or industry for many times by violence, threats or other means".

　　Article 12 of the Opinion also clearly stipulates that if all members or ringleaders, pickers and other important members are minors, the elderly and the disabled, they should be particularly cautious when identifying evil forces and criminal groups of evil forces.

　　After the promulgation of these opinions, it has played a great role in law enforcement for judicial personnel to comply with regulations and reasonably enforce the law. Liang Jian, vice president of Criminal Court No.1 of Zhejiang Higher People’s Court, once told the media: "The trial and judgment of each case will play a leading role in the direction. Therefore, we should be particularly cautious in handling cases of eliminating evils. ‘ Don’t pull high or lower ’ " .

　　Zhang Jun, the Procurator-General of the Supreme People’s Procuratorate, repeatedly stressed: "We should adhere to the rule of law thinking and the rule of law, and strengthen the awareness of procedure and evidence.". This is also the meaning of "special caution".

　　In the Selected Editions issued by the Supreme People’s Procuratorate, every case involving black and evil has been sorted out and discussed in detail according to this standard, forming a complete evidence material, ensuring "accurate and solid". For example, in the case of "Cheng Moumou, Huang Moumou and other 14 people organizing, leading and participating in underworld organizations", in addition to the crimes that have been identified, according to the recommendations of the procuratorial organs, the public security organs set up a special case-handling team to supplement 117 volumes of evidence materials.

　　If these two elderly people are really "involved in triad activities", the Public Security Bureau of Pizhou City should, in accordance with the spirit of the opinions of the National Anti-triad Office, release more detailed and powerful criminal evidence to the public in the follow-up investigation, clarify doubts to the public in time, and enforce the law transparently.

　　"Every case can stand the test of history and law, so that the social atmosphere can be clearer and the people can gain a sense of happiness and security, which is more substantial, more secure and more sustainable." At the end of this issue of Focus Interview, the host made a conclusion with such a paragraph.

With the division of three districts in Shanghai, many offline stores of chain restaurants and supermarkets are gradually recovering.

"It is expected that more than 20 guaranteed restaurants will be opened this week, distributed in 12 districts of Shanghai." On April 13th, Shanghai McDonald’s told The Paper (www.thepaper.cn) that the company has been communicating with relevant departments in the territory, hoping to continue to do a good job of ensuring and open more restaurants.

On April 13th, Jinshan Store in RT Mart, Shanghai resumed business. "All disinfection work has been completed before the store opens, and all staff members wear protective clothing."

On April 12th, an earlier day, Metro Shanghai Songjiang Shopping Mall also officially opened offline stores, and carried out store activities according to the principle of current restriction.

At present, Lianhua Supermarket and Century Lianhua under Bailian have a total of 545 Shanghai direct stores and franchise stores, and all employees in the stores must be tested and confirmed according to the government’s nucleic acid requirements before they can take up their posts.

As of the evening of April 12, Box Horse Neighborhood has reopened 47 self-promotion points in Shanghai, and Box Horse Fresh Life Store is also preparing to resume work. More than 400 employees have come to Shanghai from more than 20 cities across the country. It is estimated that the number of rescue teams will reach 1,000 before April 15th.

Chain catering: Some stores have resumed business and support take-away orders.

During the epidemic, many Shanghai residents changed their tastes by eating fast food chains such as KFC or McDonald’s. Starting this week, these needs are expected to be gradually met.

The Paper reporter learned from KFC that on April 10th, seven KFC stores were the first businesses to resume business in Songjiang District. Affected by the epidemic, at present, all stores only support delivery orders, and the products that can be ordered have not been fully restored.

It is understood that because KFC stores require closed-loop management, employees who are confirmed to be on duty should go through the relevant procedures the night before, and then all will move to the store until they are unsealed and cannot leave. KFC said that other stores are also preparing for the resumption of work and will open one after another.

"The Dongkuo store in Xuhui District is open!" On April 10th, a Burger King employee said that with the strong support of government departments, the first Burger King restaurant has officially resumed business since April.

On April 13th, The Paper reporter learned from Burger King that two stores, caolu town Hengyue Rongxin Plaza Store in Pudong District and Dahua Hucheng Store in Putuo District, are expected to resume business within one week.

Since March 28th, McDonald’s has taken the lead in opening the first batch of guaranteed restaurants in Pudong. At present, four restaurants have opened, including Huangpu Dapuqiao Store, Hong Kong Mingdu Store, Jinshan Macalline Store and Pudong Changtai Plaza Store. Since then, there have been No.1 shop in Tianyaoqiao Road, Xujiahui, Minhang Jiaotong University, McDonald’s Drive-thru in Meijiabang Road, Mei Chuan Road and Changqiao Store in densely populated areas.

It is reported that residents can place an order in McDonald’s App, and 3 copies can be delivered. "Due to the limited capacity during the epidemic, residents place orders on a first-come-first-served basis." A McDonald’s employee said that there are currently more than 200 employees and delivery staff supporting the guarantee.

According to the news of Shanghai Consumer Protection Committee on April 12th, many take-away merchants have resumed business, including more than 200 stores such as Zuoting Youyuan Fresh Beef Hot Pot (Jiangqiao Wanda Store), Ziyan Baiwei Chicken Park Store in Jinshan District and Renmin South Road Store in Luckin Coffee, Fengxian District. The distribution scope of the merchants is 2 to 3 kilometers.

It should be reminded that under the epidemic situation, the main function of these chain restaurants is to guarantee supply, and only support take-away orders, not eating in the hall.

Shop under the supermarket in the prevention area: disinfection, nucleic acid and current restriction

Not only catering enterprises, but also major supermarkets actively organize qualified stores to resume business.

On April 13th, The Paper reporter learned from Bailian that Lianhua Supermarket and Century Lianhua under Bailian currently have 545 direct stores and franchise stores open to the outside world. "As more employees of stores in the prevention area return to their posts to participate in the insurance supply, the manpower that stores can invest has also increased by 20%."

At present, among the 10 stores in Songjiang District, 8 stores located in the prevention area have resumed business; Three stores in Jinshan District were also notified on April 11th to resume offline business. In addition, 39 Lianhua stores in Chongming and 9 Lianhua stores in Fengxian have resumed business.

After the resumption of work, the prevention and control of epidemic situation in stores has become a top priority for enterprises. Lianhua Supermarket and Century Lianhua said that in addition to deep disinfection every day, all offline stores also regularly disinfect weighing areas, escalators, service desks, trolleys and other areas. "Lianhua stipulates that all employees in the store must be tested and confirmed according to the government’s nucleic acid requirements before they can go to work, and wear masks all the time, and go to work after daily temperature measurement."

RT Mart Jinshan Store, which just resumed offline business at 9: 00 on April 13th, has more than 300 customers in just one morning. "Young people mainly buy ready-to-eat goods such as cola, milk and self-heating hot pot, while middle-aged and elderly people mainly buy pork, beef, vegetables and fruits."

RT Mart Jinshan Store said that all disinfection work had been completed before the store opened, and all staff members were wearing protective clothing, and the business hours were from 9: 00 to 17: 00. Customers who arrive at the store need to hold a Temporary Entry and Exit Pass, a 48-hour nucleic acid report, and register their names and telephone numbers before going to the store for purchase.

In the RT Mart store, employees wear protective clothing.

On April 12, Metro Songjiang Shopping Mall also officially opened its offline stores, and the whole store was strictly sterilized before opening. It is reported that mall employees can only take up their posts in strict accordance with the requirements of government epidemic prevention policies, and wear protective clothing, N95 masks, protective masks and gloves.

"The store will strictly implement the current restriction measures. Customers who enter the store must wear masks, take temperature measurements and scan the place code before entering the store, and at the same time strengthen the’ safe distance’, and always remind customers to keep an interval when queuing, cashier and shopping, and maintain an appropriate spacing." Zhang Zhenhua, general manager of Metro Songjiang Shopping Mall, said.

In a special period, Metro Songjiang Shopping Mall also provided a "green channel" for special customers, and customized a "mother-to-child non-contact distribution scheme" for young mothers in surrounding communities. Zhang Zhenhua introduced that customers place orders online, and the dispatcher helps to scan the code out of the warehouse, and then gives it to the courier for distribution. "This special channel solves the baby’s ration problem and has also won the praise of the mother group."

Metro Songjiang Shopping Mall, the cashier area is separated by one guest.

Online Shangchao: Many companies have been restarted, and they will not close their doors.

With the arrival of "reinforcements", Shanghai Boxmabao Supply Store also "slowed down".

As of 10: 00 on April 13th, more than 400 Boxma employees have arrived from more than 20 cities across the country. It is estimated that by April 15th, the number of rescue teams will reach 1,000, covering all kinds of jobs such as store management, warehouse planning, picking and packaging, logistics and distribution.

Before leaving, a box horse employee of Chengdu Aid had a bald head. "It’s not to cut your hair, but to prepare for a long-term battle." In the bags of employees who aid Shanghai, anti-epidemic drugs are stuffed to the brim.

The Paper reporter learned from Box Horse that as of the evening of April 12th, Box Horse Neighborhood had reopened 47 self-help outlets in Shanghai, and Box Horse Xiansheng stores were also preparing to resume work.

"Carrefour’s online stores in Shanghai have doubled compared with last week." On April 12th, Carrefour Shanghai told The Paper that there were still some stores waiting for the environmental assessment or the environmental assessment report. It is estimated that by the end of this week, 80% of Carrefour’s online stores will be operational again. According to the estimation of about 30 Carrefour stores in Shanghai, 24 stores will open online orders by the end of this week. In addition, Carrefour’s online stores in Shanghai support the offline self-raising of neighborhood committees.

Most supermarkets have also restarted online services to protect the citizens’ "food basket". At present, there are also 16 online stores in RT Mart, where customers can place orders through RT Mart Youxian APP and Taobao Taoxianda, and merchants arrange delivery. In addition, Shanghai Metro Putuo, Jiading, Jinshan, Qingpu, Hongkou and other shopping malls can place orders through the online APP.

From April 12th, Tianlin Store and Lingyun Store in Wal-Mart’s hypermarket restarted online order service. Wal-Mart said that in view of the distribution problem of rising temperature in Shanghai, in order to ensure the freshness of distribution, Wal-Mart will add ice bags to all fresh food and then pack it in insulation bags.

In addition, in addition to the normal operation of Qingpu Store, Beicai Store in Sam has resumed work since April 9, and its service coverage has been expanded. Waigaoqiao Store is also making relevant preparations for the resumption of work. "Whether it is Sam or Wal-Mart, the stores that are now returning to work are still mainly based on supply guarantee and online order fulfillment. Now there is no way to open to the public."

At present, pure electric mini-cars can be seen everywhere in our domestic streets. Among them, Wuling Hongguang MINIEV has become the first choice for many young car fans because of its close price and low car cost. In the past six months, it has sold 104,660 cars, which shows its popularity in our domestic auto market. Recently, Xiaobian learned from the official FAW Pentium that its brand-new pure electric mini-car-Pentium Pony has officially ushered in the market, and the official guide price range is: 2.69-31,900 yuan. In order to meet the car purchase needs of different car fans, this new car has launched a total of three configuration models to choose from. Will its arrival become the strongest opponent of Wuling Hongguang MINIEV? Let’s take a look at it with Xiaobian.

First of all, in terms of styling design, Pentium Pony, as a pure electric mini-car, adopts the popular closed grille design, with the charging interface under the huge LOGO logo, and the sharp headlight groups on both sides, which makes it look cute and cute. It is worth mentioning that because the price of the new car is close to the people, the headlights are all halogen light sources and only equipped with slow charging interfaces, which I believe most friends can accept. The side body looks very simple, the door handle is traditional, with a double-door design, providing four seats. In addition, the new car also adopts the current popular two-color design. In order to cater to the aesthetics of different younger brothers and sisters, Pentium Pony will also provide six body colors: camellia green, indigo blue, bubble blue, jasmine white, peach powder and cheese white (pearlescent white).

In terms of body size, the length, width and height of the Pentium pony are 3,000/1,510/1,630mm, the wheelbase is 1,953mm, and the minimum ground clearance is 130mm. Thanks to its short and compact body, it is very flexible to drive, and it can make you easily control whether facing a narrow parking space or a crowded road. In terms of interior design, Pentium Pony looks very simple, and the knobs and buttons in the central control area are clearly and regularly laid out, which is conducive to the driver’s daily and convenient operation. In addition, the new car also provides five interior color schemes: beach gold, peach powder, bubble blue, indigo blue and camellia green. The whole system comes standard with practical configurations such as main driver airbag, manual air conditioner, rear parking radar and remote control of mobile phone App, and the top models are also available.

In terms of power, Pentium Pony is equipped with a rear-mounted single motor, with a maximum power of 20 kW and a maximum torque of 85 Nm. In addition, the new car also provides lithium iron phosphate batteries with a capacity of 9.4 kWh and 13.9 kWh, and the CLTC’s pure electric cruising range is 122 km and 170 km respectively. It is worth mentioning that the minimum power consumption of the new car is only 8.8kW·h (that is, 8 kWh) per kilometer. On the whole, Pentium Pony, as a pure electric mini-car, is not only low in price and low in cost, but also very online in face value. If you had to choose, what would you choose, Wuling Hongguang MINIEV and Pentium Pony? Welcome to communicate and discuss together below. (Text/18)

CCTV News:According to the latest influenza surveillance released by China CDC, since January, the positive rate of influenza virus detection in southern and northern provinces of China has been declining, but the number of respiratory diseases in various places has remained at a high level, and cough patients account for a relatively high proportion of the patients. Some hospitals have also set up cough clinics for this purpose.

According to the doctor, cough is actually a protective reflex of the human body and a natural reaction of the body to remove foreign bodies and secretions from the respiratory tract. In the interview, the reporter found that many patients, especially children, have recovered from respiratory diseases, but their cough is still not good. Most of them are irritating dry cough or cough accompanied by a small amount of white mucus, and there is nothing abnormal after chest X-ray examination. Many parents feel very anxious because of the chronic cough. The doctor suggested that we should first judge whether the cough is acute or chronic. If it is chronic, it is recommended to confirm whether there is a potential disease.

Shen Kunling, Chief Physician, Department of Respiratory Medicine, Beijing Children’s Hospital Affiliated to Capital Medical University:That is, more than 4 weeks, we call it chronic cough, but within 4 weeks, it is called acute cough, so some children, for example, are basically cured in 2, 3 and 4 weeks, and this is no problem. However, some patients will cough for more than 4 weeks. There are several reasons to consider. The first one is that the original A stream may be particularly heavy, or there is B stream after A stream, or mycoplasma after A stream, or bacterial infection after A stream. This mixed infection will cause serious damage to that epithelium, so he will continue to cough; Another situation depends on whether the child has a basic problem. The most common basic problem is that the child has allergies.

[Expert Tips] Avoid blindly relieving cough and abusing antibiotics.

The doctor said that cough after respiratory tract infection is very common. If it lasts within 4 weeks and there is no aggravation, there is no need to go to the hospital repeatedly. In the home care of post-infection cough, the most common misunderstanding is blind cough suppression and abuse of antibiotics. Abuse of cough inhibitors may inhibit the natural cleaning process of respiratory tract and prolong the course of disease.

Shen Kunling, Chief Physician, Department of Respiratory Medicine, Beijing Children’s Hospital Affiliated to Capital Medical University:Children still do not advocate the use of central antitussive drugs. First, cough has its own protective effect on the body. After another reason is removed, in fact, many coughs will be relieved. Many parents were very anxious, and then they started taking drugs when they coughed. They used drugs indiscriminately and asked him what drugs he used. He said that I used antibiotics, and he didn’t know what antibiotics you asked. These antibiotics are left over from the last illness, so I’ll give them to him now. In fact, this is not standardized. First of all, it is abused, then it is useless when it should be used, and there is not enough course of treatment when it should be used. These will cause the child’s condition to persist.

Experts remind that antibiotics are only effective for bacterial infections, and the functional development of children’s organs is still not perfect. Improper medication may cause some adverse reactions, causing organ damage and so on. Children are not a miniature version of adults, and it is not advisable to abuse drugs or use drugs at will. We must consider the safety and effectiveness of drug use and standardize drug use under the guidance of doctors or pharmacists.

[Expert tip] Correct atomization treatment can relieve chronic cough.

No matter what causes the recovery of chronic cough, it needs a process, during which children cough frequently and even affect eating and sleeping. At this time, doctors will suggest using atomization to relieve symptoms. So what problems should we pay attention to when doing atomization?

Although atomization therapy is very common in clinic, in the interview, we learned that there are still many parents who think that once atomization therapy is used, the child’s condition is more serious. In fact, atomization inhalation is a means to help the mucosal barrier recover. By inhaling aerosol containing drugs, it directly acts on the lesion, reducing mucosal inflammation, reducing sputum and helping the mucosal recovery. When the mucosal recovery is good, the cough will naturally be alleviated. At present, atomization treatment is mainly aimed at post-infection cough, infant wheezing, cough variant asthma and so on.

Shen Kunling, Chief Physician, Department of Respiratory Medicine, Beijing Children’s Hospital Affiliated to Capital Medical University:Generally speaking, we should master the principle of five R’s in drug use, that is, five correct patients, the right drugs, the right way of use, the right course of treatment, the right devices and so on. The effect of atomization in crying state is worse than that in quiet state, so it is best to let children be quiet, such as watching cartoons, and inhale normally in quiet state. In addition, we should pay attention to the course of treatment and have enough courses of treatment.

　　In summer, the weather is hot, and the growth and reproduction of bacteria are increasingly active. The so-called "illness from the mouth", when cooking dishes, do you think that there may be "dangerous elements" hidden in the kitchen? What diseases will they cause?

　　What are the common pathogens in the kitchen?

　　1. Escherichia coli

　　● Can cause diseases: sepsis, infective endocarditis, liver abscess, peritonitis, pelvic inflammatory disease and urinary system infection.

　　● Post-infection symptoms: abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock.

　　E. coli is harmless to human body under normal circumstances, but it is easy to cause disease once it is overdosed and human immunity is weak.

　　● E.coli has low requirements for living conditions, and it will grow in the kitchen where there is a little water or food residue, such as chopping boards, rags and sinks that have not been dried. It is warm and humid in summer, and the growth and reproduction of Escherichia coli is very fast.

　　● Escherichia coli is not resistant to high temperature. Generally, it can be killed in plain areas by boiling at 100℃ for about 15 minutes to 30 minutes. When the temperature is about 4℃, the growth rate of Escherichia coli slows down; When the temperature is below MINUS 20℃, it enters a dormant state and stops breeding.

　　2. Listeria

　　● Can cause diseases: fetal arrest, abortion, meningitis.

　　● Post-infection symptoms: abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock.

　　Listeria is known as the "refrigerator killer" and can still grow at 4℃. Milk, yogurt, eggs, meat, cold drinks and vegetables in the refrigerator may be parasitic.

　　Low high temperature environment is easy to kill Listeria, and refrigerated food can be sterilized by boiling and heating. In addition, regular cleaning and disinfection of the refrigerator will help to eliminate Listeria.

　　3. Vibrio parahaemolyticus

　　● Can cause diseases: gastroenteritis, acute renal failure and wound infection.

　　● Post-infection symptoms: severe abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock may occur.

　　● Vibrio parahaemolyticus mainly lives in seafood such as fish, shrimp, crab, shellfish and seaweed. Eating food containing this bacterium or being scratched by food containing this bacterium can cause infection.

　　● Vibrio parahaemolyticus can be killed by heating at high temperature. If sterilized with boiling water, it is recommended to boil for more than 15 minutes.

　　4. Salmonella

　　● Can cause diseases: bacteremia, septicemia, gastroenteritis, osteomyelitis, meningitis, vascular implant infection and bone and joint infection.

　　● Post-infection symptoms: persistent high fever, abdominal pain, diarrhea, nausea, dizziness, vomiting and shock may occur.

　　Salmonella is easy to appear in kitchen knives, chopping boards, vegetables, fruits, eggs, chicken legs and other foods.

　　Salmonella can be killed by heating at high temperature.

　　5. Staphylococcus aureus

　　● Can cause diseases: meningitis, otitis media, septicemia, pneumonia, folliculitis, wound infection and paronychia.

　　● Post-infection symptoms: skin pustules, abdominal pain, diarrhea, fever, vomiting, dizziness, etc.

　　● It is often parasitic on human and animal skin, nasal cavity, throat, stomach and other tissues, and is also found in air and sewage. When eating food contaminated by the bacteria, or when the body wound comes into contact with pollution sources, it can cause infection.

　　Staphylococcus aureus has a certain tolerance to high temperature, and it can be killed in a high temperature environment above 80℃ for 30 minutes. 70% ethanol can also be used for disinfection.

　　The doctor reminded that the symptoms caused by these pathogenic bacteria when invading the human body have many similarities, such as diarrhea, abdominal pain, fever, etc. Therefore, once an infection occurs, it is necessary to go to the hospital for examination and test to accurately identify which kind of bacteria is caused, and then take medicine for the symptoms.

　　Transfer from: CCTV Finance

Original health wish you health magazine

Nine cancer patients in one family?

This really sounds scary, and it’s even scarier to think about it.

Nobody wants this to happen to them, so what is "unusual" about this family? What’s the warning for you and me?

Shocked!

A family of nine cancer patients

There is a lady Luo in Zhejiang who has just given birth to a second baby and was diagnosed with undifferentiated thyroid cancer.

This is already a very unfortunate thing. Ms. Luo recalled the past and found that her family seemed to "rush" with the tumor. There were 8 cancer patients in the whole family before!

Grandma, father, brother, two aunts, an uncle, two cousins, and counting herself, nine people suffered from cancer one after another. This unusual phenomenon aroused Ms. Luo’s vigilance, so she came to Zhejiang Cancer Hospital for help.

Doctors tested the genes of Ms. Luo and 18 members of her paternal family, and finally found that this family suffered from a rare autosomal dominant genetic disease-Li-Fraumeni syndrome.

//

Leigh-Fraumeni syndrome is a rare hereditary tumor syndrome, which is mainly caused by the mutation of tumor suppressor gene TP53, and can lead to the occurrence of different cancers in multiple organs, including breast cancer, soft tissue sarcoma and leukemia. People who carry this mutant gene have an increased risk of developing tumors, and most of them occur when they are young.

pay attention to

"Family cancer" is not all genetic diseases.

In fact, it is not a new secret that cancer has the characteristics of family aggregation.

Give a famous example.

Anita Mui is a favorite star of many people. Everyone knows that Anita Mui died of cervical cancer in 2003.

But many people don’t know that the Mei brothers and sisters are all cancer patients. Her sister Mei Aifang died of cervical cancer, her brother Mei Deming died of laryngeal cancer, and Mei Qiming was also diagnosed with colorectal cancer.

The reason why cancer has family clustering is because the occurrence of cancer is really related to genetic factors.

Leigh-Fraumeni syndrome is not the only genetic disease related to tumor, and the common hereditary breast cancer, ovarian cancer syndrome and Lynch syndrome (the most common colorectal cancer and endometrial cancer susceptibility syndrome) belong to it.

Genetic diseases associated with tumors generally have several characteristics:

//

Many people in the family are sick.

The onset age is young (usually < 50 years old or even earlier)

The same patient has multiple or bilateral tumors.

However, "family cancer" is not all related to heredity.

Because the living environment and eating habits of a family are close, sometimes there will be some family clustering cases unrelated to heredity.

For example, if a family eats moldy grains or drinks polluted pond water for a long time, the risk of liver cancer in this family will be much higher than that in the average family, and there may be many cases of liver cancer in the family. But this clustering disease is not caused by heredity, but by environmental pollution and eating habits.

Q:

What if someone at home has cancer?

The so-called "family history of tumor" means that first-degree relatives and/or second-degree relatives have malignant tumors.

//

First degree relatives: parents, children, brothers and sisters.

Second degree relatives: grandparents, uncles, uncles, aunts, uncles and aunts.

In other words, there are cancer patients in the family with a family history of cancer.

People who usually have a family history of cancer will have a higher risk of cancer than those who have no family history of cancer, and the risk of some malignant tumors may even exceed the general population by ten times.

If only one person in the family has cancer, don’t be overly nervous; However, if 2-3 members of the immediate family have cancer, they need to be highly suspected of familial cancer tendency. They can do related tumor genetic counseling and genetic testing, analyze the causes of cancer among many family members, and strive to achieve early detection, early prevention, early diagnosis and early treatment.

At the same time, we should also re-examine the family’s living environment, living habits, especially eating habits, and rule out some cases of tumor clustering caused by environment and diet (rather than heredity).

However, please note that tumors with definite genetic factors still account for a small number of the total incidence of cancer, only 5%~10%, and more cancer patients are sporadic cases.

Therefore, everyone should keep this tumor screening suggestion form in mind to help us stay away from tumors as much as possible.

-Produced by the editorial department of "I wish you health" of Jiangsu Phoenix Science and Technology Publishing House-

Content Planning/Writing/Typesetting: Zhu Jingjing

Original title: "A family of 9 cancer patients? Is it safe for me to have a cancer patient at home? 》

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　　　　　　 CCTV News:On the afternoon of 19th, the State Council Joint Prevention and Control Mechanism held a press conference on the State Council Joint Prevention and Control to introduce the prevention and control of epidemic situation in autumn and winter, and the role played by medical and health workers in fighting the COVID-19 epidemic.

Guo Yanhong, Ombudsman of Medical Administration and Hospital Authority

　　　　　　 Guo Yanhong, Ombudsman of the Medical Administration and Hospital Authority, said that as we all know, medical personnel are an important force in maintaining and promoting people’s health and the main force in promoting the healthy development of medical and health undertakings. The team of doctors is an important part of the medical staff in our country. The CPC Central Committee and the State Council attached great importance to the construction and development of doctors’ team, especially since the 18th National Congress, and adopted a series of effective measures to strengthen the construction of doctors’ team, especially from the aspects of practice management, education and training, financial investment and treatment guarantee, including their rewards and recognition, etc., to strengthen the implementation of work and promote the construction and development of doctors’ team.

　　　　　　 In the construction and development of doctors, remarkable achievements have been made in recent years. First of all, the team of doctors is growing and their ability level is improving. By the end of 2019, the total number of doctors in China reached 3.867 million, an increase of nearly 830,000 compared with 2015, an increase of 27.2%. Among the doctors, bachelor degree or above accounted for 57.4%, an increase of 8 percentage points over 2015. Second, the construction of grassroots doctors has achieved results. In our country, under the guidance of strengthening the grassroots, the construction of doctors in grassroots medical and health institutions has made great progress in recent years. By the end of 2019, the number of doctors in primary health care institutions reached 1.437 million, an increase of 335,000 or 30.4% over 2015. It can be seen that the growth of the number of grassroots doctors is much higher than that of the overall number of doctors. Third, through key support, it has also achieved results in the construction of some weak professional doctors. For example, the number of doctors who are in short supply in pediatrics and psychiatry has increased rapidly in recent years. Doctors who specialize in pediatrics have reached 234,000 in 2019. The construction, ability level, overall structure and layout of the medical team have been steadily improved, and the medical team is moving from high-speed growth to high-quality development. The majority of doctors, together with the majority of medical workers throughout the country, have also made active efforts in providing medical services and improving people’s health.In 2019, the number of medical and health institutions in China reached 8.72 billion, an increase of 4.9% compared with 2018 and 13.4% compared with 2015. In terms of the number of hospitalizations, the number of hospitalizations in medical and health institutions nationwide in 2019 was 266 million, an increase of 4.5% over 2018 and 26.3% over 2015. Judging from the overall growth of medical services, the majority of medical staff have made efforts to improve the overall medical service capacity and quality and promote the health level of the people with professional skills and knowledge.

　　　　　　 We hope that in the next step, all relevant departments in China will make concerted efforts with Qi Xin to build, ensure and develop the team of doctors, so as to benefit all the people with better services and make the team of doctors better contribute to the construction of a healthy China.

Friends, we are really tired of eating melons.Zhang Xiaohan, who is not very reliable, has drawn cartoons again!

This time, she still rushed to the hot search with ambiguous melons. According to her description, a "first-line intellectual actress" who is famous for her urban drama met with a married rich man in a hotel in Hainan, and the rich man also sent the actress high-luxury jewelry worth tens of millions to make her happy …

Regardless of whether this melon is real or not, who will take care of Zhang Xiaohan! Put it directly with a hammer. Stop drawing cartoons! Few of the comic books she drew before have ever come true …

But this netizen is right. People’s curiosity can’t be suppressed. Although we scold Zhang Xiaohan for having no credibility, we still can’t help but look for an "intellectual actress" who can sit in the right place according to the information disclosed.

Some netizens have even started to list the names of qualified actresses, such as Jiang Shuying, Dilraba, Angel, Chen Shu, Song Jia Jr., Sunny, Chen Douling, Wu Jinyan … The appraisal criteria are based on the paparazzi’s phrase "an intellectual actress who is famous for her urban drama".

Among them, Jiang Shuying was listed as the most likely actress by netizens because of too many details.

First of all, Jiang Shuying was really helped by the fire in Nothing But Thirty, and she did play a lot of urban dramas herself. It can be said that when I saw her face, I couldn’t help but think of urban female roles such as Jiang Lai and Wang Manni.

Recently, in Ode to Joy 3, Jiang Shuying still plays an urban white-collar Ye Zhenzhen.

Secondly, Jiang Shuying really went to Hainan recently and had a beautiful photo. In the photo, she has long hair, and the red flower in her ear seems to echo the red flower on the plate in Zhang Xiaohan’s cartoon.

As it happens, Jiang Shuying has also sent several selfies recently, and the jewels in the selfie are particularly eye-catching. Immediately, some netizens said: "Is this the jewelry sent by a wealthy businessman, so it is the show of love?"

However, some netizens immediately clarified that they searched for the same model in Jiang Shuying’s selfie. The bracelets and watches are more expensive, but as an actress in Jiang Shuying’s coffee spot, she can afford them. The necklace is only a niche brand with more than 1,000 pieces, which can’t reach the level of "ten million yuan jewelry" at all.

Jiang Shuying and his studio also denied this speechless rumor., the tone is full of helplessness:"I can be talked about, but I can’t be framed."

Then netizens found out that,The characters of wealthy businessmen and wives in cartoons seem to be very similar to those of Yu Dong, president of Bona Film, and his wife Jin Qiaoqiao., just Jin Qiaoqiao also dyed red hair.

After reading the so-called "evidence" dug up by these netizens, my little sister is completely speechless, and everyone’s ability to learn from the melon is really getting better and better!

Then Jin Qiaoqiao sent a message to respond to this matter:"Rumors stop at the wise! Watch more movies when you have time. "

Later, Jin Qiaoqiao replied to the comments of netizens in the comment area. In the face of the "persuasion" of netizens, my sister said that she was too speechless:"Can you don’t believe those false news that are fabricated and maliciously slandered on the Internet! It’s all fake! Fake! Fake! " "This netizen? Can you have a little brain? "

There are even netizens who call Jin Qiaoqiao the "little three" of Yu Dong, and Jin Qiaoqiao is so angry that he directly returns.: "Who are you talking about? Spread rumors? ! If you don’t get it, you have to take a lawsuit! "

Here, my little sister wants to get a word in,Jin Qiaoqiao clarified the "mistress" as early as 2014.Yu Dong ended his first marriage in 2010, and he and Jin Qiaoqiao only met in 2012, so there is no such thing as "mistress intervening".

Then Jin Qiaoqiao called Zhang Xiaohan, saying that he was also curious about who the three people in his cartoon were, and had to say that Jin Qiaoqiao was somewhat domineering!

Speaking of Jin Qiaoqiao, I believe that everyone’s first impression of her is stillThe charming and charming peacock princess in the 98 edition of The Journey to the WestOk! It is this role that opened her up.The road of "princess professional household".

The second princess in the East China Sea in "Pig Eight Rings in Spring" is also unforgettable, and Jin Qiaoqiao’s delicate, expensive and sweet appearance is really very suitable for playing the princess.

Princess Yuzhen in "The Secret History of Yang Guifei" is even more compassionate. Some netizens even commented that she is very "Guanyin" and has a kind face and a beautiful face.

Because of her extraordinary and recognizable beauty, Jin Qiaoqiao has been quite successful in her career since she graduated from Nortel, which is enough for most students to envy.

It is said that you can’t have both career and peach blossom, but Jin Qiaoqiao is different, and her peach blossom has never been bad.

No, Jin Qiaoqiao’s first love was vigorous enough. He directly held hands with Wu Qihua, the top student of TVB at that time, and officially announced his love affair. If this were put in today, it would be enough to paralyze the server.

At that time, Jin Qiaoqiao was quite pure and beautiful, and her figure was full of pure desire. She was a little girl with a happy face. Look at this dress, it is not out of date now!

Although Jin Qiaoqiao’s mother thinks that Wu Qihua and Jin Qiaoqiao are too different in age and somewhat introverted, she thinks that her daughter will not be happy to live with him.

But when the two were in the thick of love, they couldn’t listen to their parents’ thoughts at all.Wu Qihua even bought a mansion in Shanghai and gave it to Jin Qiaoqiao in the name of "wedding room"It is said that it cost 1.6 million, which was 1.6 million in 2003.

The good times didn’t last long, and the two finally broke up.After all, Wu Qihua is a "playboy" with too much romantic history, and it is really difficult to get results in falling in love with him.

Later, Jin Qiaoqiao has been caught in various scandals, but there has been no "positive fate".

For example, Jin Qiaoqiao, the unspoken rule of Zhang Guoli, was also caught by Deng Jie (although it seems that there is no real hammer at all now, it is just an empty talk and a visual sense) ↓

Some netizens broke the news that they had picked up Jin Qiaoqiao’s mobile phone, saying that Jin Qiaoqiao had received an ambiguous text message from a wealthy businessman who wanted to pay for her dinner date. The text message boasted:"We are not short of money, what price, Miss Jin can say. Whatever you want, we will never make a counter-offer. "

It’s not a scandal, can only say that the entertainment circle at that time was really in hot water …

Jin Qiaoqiao’s second love affair was with Yu Dong, CEO of Bona Film, and they went straight to the marriage hall. Jin Qiaoqiao also gave birth to a son and a daughter for Yu Dong.

I mean, I’m really principled, and I don’t talk much about love, either talking about being popular or talking about movie mogul.

After marrying the president, Jin Qiaoqiao is almost in a state of retirement. She has been working as a full-time mother at home, and her personal social accounts also record anecdotes about her children’s growth, and only occasionally does Yu Dong appear.

Netizens are deeply touched by this.In the past, the goddess became a child nanny after marrying into a rich family, or was she a "widowed baby"!

E-mail flipped through Jin Qiaoqiao’s account and found that there were not many children’s fathers.

Either take your children out with your parents ↓

Or take two dolls to the playground by yourself.

Recently, however, some netizens ran into Jin Qiaoqiao and Yu Dong to take the children to Universal Studios. My son took his mother’s hand and Yu Dong touched his son’s head while listening to the voice. The picture was quite warm. It seems that they were very happy, and netizens were also worried about it.

Although Jin Qiaoqiao has been a stay-at-home housewife for many years, it seems that her life is empty and her career is barren, but at least she is also a serious "Bona boss".

It’s up to her to hold a birthday party, and almost half of the big coffee in the entertainment circle came to celebrate her birthday., Jason Wu, Iola, Jet Li, Tung shing Yee, Xiang Huaqiang, Xiangtai, Zhang Ziyi, Li Xiang, Chiu Man-Cheuk, Pu Cunxin, Fan Ming, Fu Disheng, Ren Jing, Chen Xiao, Huang Yi, Tan Jing, Chen Xuedong … How many female stars can do this in-plane entertainment?

Jin Qiaoqiao had nothing to do but open a hot pot restaurant to kill time. Stars such as Yao Chen, Jerry Lee and Lin Yongjian rushed to call her new store, and her contacts were quite amazing.

Perhaps the family can also be a woman’s career. Although Jin Qiaoqiao has been away from the entertainment circle for many years, who said that it is not a real skill to run the family well? (text/seedling bag)

Mesenchymal Stem Cell (MSC) have unique biological characteristics and therapeutic potential, and are becoming a "new star" in the field of disease research, and the research enthusiasm continues unabated. MSC involves many related researches, such as multiple sclerosis, arthritis, neuropathic pain, intestinal diseases, etc., and is a research hotspot in the field of transplantation and autoimmune diseases.

Statistics on the number of published papers in MSC field from 2014 to 2024, with data from Pubmed.

Mesenchymal stem cells (MSC) are pluripotent stem cells derived from mesoderm with high self-renewal and multi-lineage differentiation potential. They are widely distributed in various tissues of the whole body, with the advantages of easy separation and easy acquisition, and can be differentiated and expanded in vitro.

MSC is an excellent tool for tumor therapy and gene transfer research, functional genomics, drug screening, Qualcomm screening and toxicology. International Association for Cell Therapy (ISCT) defines human MSC as:

Under standard culture conditions, it is adherent growth;

CD105, CD73 and CD90 should be expressed, but CD45, CD34, CD14 or CD11b, CD79α or CD19 and HLA-DR surface markers should not be expressed.

It can differentiate into osteoblasts, chondrocytes and adipocytes in vitro.

Mesenchymal stem cells come from a variety of cells or tissues, such as bone marrow, adipose tissue, peripheral blood, placental tissue, dental pulp and so on. Similarly, MSC can also differentiate into many cell types, such as osteoblasts, chondrocytes, fat cells, muscle cells, nerve cells, stromal cells and so on.

The origin and differentiation of MSC (from references)

It is worth noting that the differentiation potential of mesenchymal stem cells may vary with the source of stem cells, expansion conditions and their culture microenvironment. Three-line differentiation is the focus of MSC culture and amplification. Triple differentiation usually refers to osteogenesis, adipogenesis and chondrogenesis. In order to better understand the triple differentiation of MSC, this paper preliminarily summarizes the general process of triple differentiation of MSC and the identification methods corresponding to some markers.

Osteogenic differentiation

MSC can directionally differentiate into osteoblasts under the stimulation of various cytokines and other physical and chemical environments. Then the osteoblasts further differentiated into osteoblast precursor cells and entered a rapid proliferation period. Osteoblasts synthesize and secrete organic matrix at this stage, forming osteoid (mainly type I collagen), characterized by alkaline phosphatase, which is an early sign of osteoblast differentiation and maturity; Alkaline phosphatase appears blue under the microscope after fixation with blue, while undifferentiated cells have no obvious color.

Mature osteoblasts express ECM calcification-related proteins. Long-term osteogenic induction causes calcium ions to precipitate in the form of calcium salts, forming "bone nodules". Bone nodules can be dyed deep red by alizarin red (alizarin red reacts with calcium to produce a deep red compound), and the strength of osteogenic differentiation can be expressed by the area and depth of the pigment.

Identification of osteogenic differentiation of MSC from different sources

Chondrogenic differentiation

Firstly, MSC gathers into a cluster, and the middle cells in the cluster are transformed into a large and round cell, that is, chondrocyte, through division and differentiation. Chondrocytes produce matrix and fibers (mainly type II collagen), and the expression of type II collagen was observed by immunohistochemistry.

Generally, the differentiation results of chondrocytes were identified by Alyssin Blue. Alisine blue is an alkaline dye, which can combine with nucleic acid in cells to make the nucleus dark blue. At the same time, alisin blue combined with polysaccharides in cartilage matrix, making cartilage cells and matrix light blue.

Identification of chondrogenic differentiation of MSC from different sources

Adipogenic differentiation

There are two stages of adipogenic differentiation of MSC: first, it differentiates into adipose precursor cells, and then it differentiates into adipocytes under the influence of specific stimuli (such as C/EBPs and PPAR-γ).

Cells keep accumulating fat droplets in the cytoplasm and getting bigger. After dyeing with oil red O, it is red under the microscope. Undifferentiated cells have no obvious color.

Identification of chondrogenic differentiation of MSC from different sources

Various factors will affect the differentiation potential. Such as culture environment, growth factors and the existence of other cells, will affect the differentiation process. Specific signal molecules, such as bone morphogenetic protein (BMP) or Wingless related integration site (Wnt), can promote the differentiation of stem cells into bone cells or nerve cells, respectively.

The research on mesenchymal stem cells is so hot that Yiqiao Shenzhou has compiled a detailed MSC operation guide. Protocol is full of dry goods, in addition to the above three-line differentiation identification examples, it also includes how to isolate mesenchymal stem cells, how to subculture and expand them, and how to determine that the expanded cells are mesenchymal stem cells. Welcome to download and learn!

Click on the link above to download the Protocol.

References:

Dragomirka Jovic. A Brief Overview of Global Trends in MSC-Based Cell Therapy. Stem Cell Reviews and Reports, 2022. https://doi.org/10.1007/s12015-022-10369-1

Xing Liang Fan, et al. Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy. Cellular and Molecular Life Sciences, 2020. https://doi.org/10.1007/s00018-020-03454-6

Yu Han, et al. Mesenchymal Stem Cells for Regenerative Medicine. Cells, 2019. doi:10.3390/cells8080886

Tilotta V, et al. Mesenchymal stem cell-derived secretome enhances nucleus pulposus cell metabolism and modulates extracellular matrix gene expression in vitro. Front. Bioeng. Biotechnol. 2023. doi: 10.3389/fbioe.2023.1152207

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　　How do soda music listen to songs together? Soda music is an easy-to-use software for listening to songs. Users can customize the process of listening to songs when using it, and they can also listen to songs with friends. This small series has prepared a detailed tutorial for everyone, hoping to be helpful to your friends.

　　1. First, turn on the soda music, and click "Three Points" in the lower right corner of the song in the recommendation.

　　2. Then click the "Download" button in the upper left corner.

　　3. After downloading, go to "My" and enter the "Download" interface.

　　4. Then find the song to share and click "Three Points" on the right.

　　5. Then select "Share" in the pop-up menu.

　　6. Finally, just choose the object we want to share.

　　The above is the relevant information brought by Xiaobian. Do you think you can help yourself deal with these problems? Like friends, come to IT Encyclopedia to watch more content.