In order to promote animal epidemiological investigation in accordance with the law, master the occurrence regularity of major animal diseases such as highly pathogenic avian influenza and foot-and-mouth disease, judge the occurrence risk and epidemic trend of animal diseases, scientifically evaluate the epidemic situation and prevention and control effect of animal diseases, and improve the prediction and early warning, risk prevention, emergency response ability and prevention and control level of major animal diseases, according to the 2010 National Animal Disease Monitoring Plan, our department organized and formulated the 2010 National Epidemiological Investigation Plan for Major Animal Diseases such as Highly Pathogenic Avian Influenza and Foot-and-mouth Disease. It is issued to you, please follow it.
I. Guiding ideology
Promote animal epidemiological investigation in accordance with the law, fully grasp the occurrence regularity of major animal diseases such as highly pathogenic avian influenza and foot-and-mouth disease, scientifically judge the occurrence risk and epidemic trend of animal diseases, systematically evaluate the epidemic situation and prevention and control effect of animal diseases, and continuously improve the forecasting and early warning, risk prevention, emergency response ability and prevention and control level of major animal diseases.
Second, the investigation method
According to different investigation purposes and tasks, the following three investigation methods are set:
(1) Emergency epidemiological investigation
When one of the following situations occurs:
1 suspected or confirmed the occurrence of highly pathogenic avian influenza and other major animal diseases;
2. Suspect or confirm the occurrence of exotic animal diseases such as mad cow disease;
3. The epidemic characteristics of major animal diseases such as swine fever have changed obviously;
4. The exterminated diseases such as rinderpest happen again.
The animal husbandry and veterinary administrative department of the people’s government at or above the county level shall timely organize the implementation of on-the-spot, retrospective and follow-up investigations, find risk factors, judge the diffusion trend, evaluate the prevention and control effect, and improve the scientific nature of emergency response to major animal diseases. See Annex 1 for the specific scheme.
(2) Designated epidemiological investigation
China Center for Animal Health and Epidemiology and provincial animal epidemic prevention and control institutions should set up epidemiological investigation points in key areas (mainly where the national animal epidemic monitoring station and the border epidemic monitoring station are located), continuously monitor the changes of risk factors in animal breeding, immunization, circulation and slaughter, and combine the serological and pathogenic monitoring results of specific animal diseases to predict the epidemic development trend, evaluate the effect of epidemic prevention and control, and improve the pertinence of prevention and control work. See Annex 2 for the specific scheme.
(3) Special epidemiological investigation
In view of the specific problems encountered in the prevention and control of major animal diseases, China Center for Animal Health and Epidemiology and relevant provincial animal disease prevention and control institutions timely launched special investigations and studies to provide decision-making consultation for animal husbandry and veterinary authorities. See Annex 3 for the specific scheme.
Third, the division of responsibilities
(1) The Ministry of Agriculture shall be in charge of the national epidemiological investigation of animal diseases, formulate and publish the national epidemiological investigation plan of animal diseases according to the national prevention and control situation, and organize its implementation. The Epidemiology Sub-committee of the National Committee of Experts on Animal Epidemic Prevention undertakes the examination and approval, demonstration, consultation and technical support of the national animal epidemic epidemiological investigation plan and important investigation conclusions.
(two) the competent departments of animal husbandry and veterinary medicine of all provinces, autonomous regions and municipalities directly under the central government shall, in accordance with this plan, formulate work plans within their respective jurisdictions in light of local actual conditions. Provincial animal epidemic prevention and control institutions shall implement the epidemiological investigation within their respective jurisdictions, and supervise and guide the epidemiological investigation of national animal epidemic monitoring stations and border epidemic monitoring stations within their respective jurisdictions. The provincial animal epidemiological investigation expert group undertakes technical support and training within its jurisdiction.
(three) the epidemiological investigation task force set up by the animal disease prevention and control institutions at the city and county levels shall specifically implement the epidemiological investigation work within their respective jurisdictions. The national animal epidemic monitoring station and the border epidemic monitoring station shall, in accordance with the requirements of this plan, undertake the epidemiological investigation and evaluation of animal diseases in the designated area and submit the epidemiological investigation information regularly.
(4) The China Center for Animal Health and Epidemiology coordinates the sub-centers and relevant veterinary laboratories, and undertakes the epidemiological investigation, analysis and evaluation, technical guidance and training of major animal diseases in China; Summarize the national epidemiological investigation and testing data, and organize the drafting of epidemiological investigation and evaluation reports. Sub-centers and relevant veterinary laboratories shall undertake or participate in the investigation, detection, analysis and evaluation of animal diseases respectively in accordance with the provisions of this plan. When necessary, the relevant veterinary laboratories shall participate in the epidemiological investigation of major animal diseases according to the requirements of the Ministry of Agriculture.
Fourth, the job requirements
(1) Strengthen leadership and clarify responsibilities.Local animal husbandry and veterinary departments at all levels should strengthen leadership, formulate work plans within their respective jurisdictions as soon as possible, coordinate relevant departments to incorporate the required funds into local fiscal budgets, and incorporate epidemiological investigation into the key work of animal epidemic prevention assessment; Ensure that animal disease prevention and control institutions organize epidemiological investigations, and coordinate animal husbandry and veterinary technology extension institutions and animal health supervision institutions to provide data on animal husbandry production and quarantine supervision. All fixed-point contact working groups should strengthen supervision and inspection of epidemiological investigations in various places. If the organization, responsibility mechanism and technical force are not fully implemented, informed criticism should be carried out. Those who affect the prevention and control of major animal diseases and cause the spread of the epidemic should be investigated for responsibility according to law.
(2) Scientific, standardized and coordinated.Local animal disease prevention and control institutions at all levels shall, in accordance with the scope, procedures and requirements specified in Annex 1, conduct emergency epidemiological investigations in a comprehensive, standardized and timely manner; China Animal Health and Epidemiology Center shall, in accordance with the tasks specified in Annexes 2 and 3, strengthen the integration of resources according to the monitoring scope specified in the 2010 National Animal Disease Monitoring Plan, coordinate the sub-centers, relevant professional laboratories, local animal disease prevention and control institutions at all levels and national animal epidemic monitoring and reporting stations (border monitoring stations), and carry out fixed-point investigations and special investigations in an orderly manner.
(3) Strengthen technical support and improve the communication mechanism.China Center for Animal Health and Epidemiology should further improve the database of animal epidemiology, timely develop relevant investigation software, mature investigation and evaluation technology, establish training programs, and strengthen technology popularization; Strengthen epidemiological analysis and evaluation, and report the progress of epidemiological investigation to the Veterinary Bureau of the Ministry of Agriculture in a timely manner. Provincial animal disease prevention and control institutions should improve the epidemiological investigation, analysis and evaluation and work report mechanism, and improve the technical support capacity in a planned way. City and county animal epidemic prevention and control institutions should carry out epidemiological investigation systematically and standardly, timely and accurately submit information, conduct regular assessment, and provide technical support for animal epidemic prediction and early warning and emergency response. Each sub-center shall report the progress of the investigation to China Animal Health and Epidemiology Center in a timely manner according to the requirements of this plan.
China Animal Health and Epidemiology Center and its sub-centers, after conducting epidemiological investigation, should exchange opinions and results on epidemiological investigation with relevant provinces in time.
V. Others
China Center for Animal Health and Epidemiology should, before March, jointly with relevant parties, draft a specific implementation plan for fixed-point epidemiological investigation and special epidemiological investigation, which will be considered and adopted by the Epidemiology Branch Committee of the National Committee of Experts on Animal Epidemic Prevention and approved by the Veterinary Bureau of the Ministry of Agriculture, and organized and implemented as soon as possible.
Annex 1: Work Program of Emergency Epidemiological Investigation
2. Fixed-point epidemiological investigation work plan
3. Special epidemiological investigation work plan
Attachment 1:
Work plan of emergency epidemiological investigation
I. Scope
Suspect or confirm the occurrence of the following circumstances, the provincial veterinary administrative department shall organize the animal epidemic prevention and control institutions in this province to start the emergency epidemiological investigation according to the requirements of this scheme, and fill in the emergency epidemic questionnaire in time:
(1) Highly pathogenic avian influenza, foot-and-mouth disease, highly pathogenic porcine blue ear disease, anthrax and rabies;
(two) the incidence or epidemic characteristics of major animal diseases such as swine fever, Newcastle disease, brucellosis, tuberculosis and bluetongue have changed abnormally;
(3) Exotic animal diseases such as Petit Ruminant, Mad Cow Disease and African Classical Swine Fever;
(four) rinderpest, contagious bovine pleuropneumonia and other eliminated diseases occur again;
(five) new cases such as swine influenza A (H1N1) and other epidemics with outbreaks or unknown causes.
Second, the purpose and task
(1) Defining the occurrence of epidemic diseases;
(two) to explore the causes and risk factors;
(three) analysis of the possible diffusion range;
(four) forecast the epidemic outbreak or epidemic trend, and put forward suggestions on control measures;
(5) Evaluate the effect of control measures.
Third, the working procedure
(a) the county-level animal disease prevention and control institutions shall immediately verify the information, conduct a preliminary investigation and report the epidemic situation according to the regulations after receiving the report of suspected emergency epidemic situation.
After receiving the report, the provincial veterinary administrative department immediately organized the provincial animal disease prevention and control institutions to carry out on-site epidemiological investigation.
(2) After further verifying the situation, the field investigators shall collect relevant information in detail, comprehensively and accurately according to the requirements of the corresponding emergency epidemiological questionnaire (Schedules 1-6) and fill in the questionnaire.
(3) On-site investigators shall, according to the investigation, describe the current situation of animal epidemic (space, time and inter-group distribution, etc.), analyze the source of epidemic, judge the development trend of epidemic, put forward suggestions on control measures, and form an investigation and evaluation report. When the spread of the epidemic is suspected, follow-up investigation should be carried out in high-risk areas.
(four) the provincial epidemiological investigation expert group shall review the investigation and evaluation report and its conclusions formed by the on-site investigators.
(five) when necessary, the China Center for Animal Health and Epidemiology and related sub-centers shall send an expert group to carry out on-site epidemiological investigation, and organize special investigations such as economic losses and assessment of prevention and control measures.
Fourth, the job requirements
(a) the provincial epidemiological investigation expert group shall review the investigation and evaluation report and its conclusions formed by the on-site investigators, and the audit opinions shall serve as an important basis for lifting the blockade of major animal epidemics.
(two) before the blockade of the epidemic situation is lifted, the provincial animal disease prevention and control institutions shall report the audit opinions of the epidemiological questionnaire, the on-site investigation and evaluation report and the provincial epidemiological investigation expert group to the China Animal Health and Epidemiology Center for the record.
(III) China Center for Animal Health and Epidemiology should improve the software of emergency epidemiological investigation as soon as possible, do a good job in technology popularization, make timely assessment of emergency measures and diffusion risks of emergency epidemic, summarize and analyze epidemic laws, and regularly report to the Veterinary Bureau of the Ministry of Agriculture.
(four) local animal disease prevention and control institutions at all levels should make clear that the person in charge of animal epidemiology questionnaire is responsible for the work.
Attachment 2:
Work plan of fixed-point epidemiological investigation
I. Routine epidemiological investigation
The national animal epidemic monitoring station and the border animal epidemic monitoring station shall, in accordance with the requirements of this plan, do a good job in the investigation of animal husbandry production, animal immunity, slaughtering and processing and livestock and poultry prices (reflecting the circulation of animals) in the county where they are located, and analyze the development trend of local epidemic situation in combination with the monitoring data of major local animal diseases.
The national animal epidemic monitoring stations and border animal epidemic monitoring stations shall regularly submit the following epidemiological investigation information to the provincial animal epidemic prevention and control institutions and the China Center for Animal Health and Epidemiology.
(1) Fill in the information on dog breeding and rabies immunization in 2009 before April 30 (see Schedule 7 for the report format);
(two) before June 30, fill in the information of animal husbandry production and slaughter processing in 2009 (see Annex 8 for the report format);
(three) before the end of each month, fill in the price information of livestock and poultry from the 21st of last month to the 20th of this month (see Table 9 for the report format);
(4) Submit the annual work report before December 15th.
Second, the provincial designated epidemiological investigation
The competent animal husbandry and veterinary departments of all provinces (autonomous regions and municipalities directly under the Central Government) shall, according to the actual situation of prevention and control of major local animal diseases, formulate the designated epidemiological investigation plan within their respective jurisdictions, and establish and improve the working mechanism of designated epidemiological investigation.
Animal disease prevention and control institutions in all provinces (autonomous regions and municipalities directly under the Central Government) should set up epidemiological investigation points according to diseases, regularly carry out fixed-point investigations on major poultry diseases such as highly pathogenic avian influenza and Newcastle disease, major livestock diseases such as foot-and-mouth disease, swine fever and porcine blue ear disease, and major zoonosis such as animal brucellosis and tuberculosis, and analyze the epidemic development trend within their respective jurisdictions in combination with the situation of animal husbandry production, animal immunization, slaughter and processing and livestock and poultry circulation in this province, and report to animals in China before December 20.
Third, the national sentinel epidemiological survey
(1) Fixed-point investigation of poultry epidemics
1.Purpose.To understand the immunity, infection and pathogen variation of avian influenza, Newcastle disease, infectious bronchitis, infectious laryngotracheitis, infectious bursal disease, viral arthritis, and major immunosuppressive diseases such as subtype J leukemia, reticuloendotheliosis and Marek’s disease in China.
2.Range.In Jilin, Tianjin, Shandong, Shanxi, Henan, Anhui, Hubei, Jiangsu, Guizhou, Ningxia, Guangdong, Hainan and other 12 provinces, three counties (cities, districts) where animal epidemic monitoring stations are located are selected as designated investigation points.
3.Method of investigation.① Investigation of clinical healthy poultry flocks: Seven sampling points (three scale farms, one administrative village and three live poultry trading markets) were selected from each investigation point, and swabs and serum samples of 30 poultry were collected simultaneously for testing, which was carried out once in March-May and September-November respectively. ② Investigation of sick birds: According to the clinical symptoms and the detection requirements of suspected epidemic diseases, the designated investigation provinces or counties collected samples of suspected sick birds and sent them to China Animal Health and Epidemiology Center for detection.
4.Undertaking unit.China Animal Health and Epidemiology Center and relevant provincial animal disease prevention and control institutions jointly implemented.
(2) Investigation of swine epidemic disease
1.Purpose.Master the development trend of swine epidemic disease; To monitor the molecular epidemiology and genetic evolution of the main pathogens of swine epidemic diseases.
2.Range.In Liaoning, Hebei, Henan, Yunnan, Guangxi, Fujian, Jiangxi, Anhui, Hunan, Sichuan and other 10 provinces and regions to carry out fixed-point epidemiological investigation.
3.Way.① Investigation of clinical healthy pigs: According to the principle of representativeness, five slaughterhouses (1 provincial capital city, 2 prefecture-level cities and 2 county-level cities) were selected in each province to carry out epidemiological investigation and sampling detection, and 15 serum and tissue samples were collected from each slaughterhouse simultaneously, which was carried out once in March-May and September-November respectively. ② Investigation of diseased pigs: Each province shall submit at least 25 samples of diseased pigs to China Center for Animal Health and Epidemiology every six months. When necessary, China Center for Animal Health and Epidemiology will conduct special epidemiological investigation and detection in relevant provinces according to the epidemic situation.
4.Undertaking unit.China Animal Health and Epidemiology Center, Lanzhou Sub-center, animal disease prevention and control institutions of relevant provinces.
(3) Fixed-point investigation of swine flu
1.Purpose.Monitor the epidemic dynamics of swine flu and the genetic evolution of the pathogen.
2.Range.Investigation on epidemic diseases in the same pig herd.
3.Ways and means.Five slaughterhouses (one in the provincial capital city, two in the prefecture-level city and two in the county-level city) and three pig farms were selected to carry out epidemiological investigation and sampling inspection in the key areas of pig raising in each province. 15 serum and nasal swabs were collected simultaneously in each slaughterhouse and pig farm, and were carried out once in March-May and September-November respectively. Every six months, all provinces send 25 samples of suspected sick pigs with influenza to China Center for Animal Health and Epidemiology. When necessary, China Center for Animal Health and Epidemiology will conduct special epidemiological investigation and detection in relevant provinces according to the epidemic situation.
4.Undertaking unit.China Animal Health and Epidemiology Center and relevant provincial animal disease prevention and control institutions.
(4) Investigation on animal brucellosis and tuberculosis
1.Purpose.To understand the infection and incidence of brucellosis and bovine tuberculosis in dairy cows and sheep, and analyze the epidemic characteristics and risk factors.
2.Range.In Heilongjiang, Jilin, Liaoning, Inner Mongolia, Gansu, Xizang, Yunnan, Guizhou, Sichuan, Qinghai, Xinjiang, Zhejiang, Shandong, Beijing, Shanghai, Chongqing and other 16 provinces (autonomous regions and municipalities directly under the Central Government), three national animal epidemic monitoring stations (border epidemic monitoring stations) with a large number of cows and sheep were selected as epidemiological investigation points.
3.Way.① Routine sampling: epidemiological investigation was carried out in the county where the investigation point was located, and 500 blood samples of dairy cows and sheep were collected from free-range households, large-scale farms and slaughterhouses in each county for testing. The specific organization and implementation of each province, China Center for Animal Health and Epidemiology provides unified training on diagnostic reagents and detection techniques, rechecks positive samples, and summarizes relevant investigation and detection data at the end of the year. ② Collection of disease samples: all provinces collect aborted fetuses from cattle and sheep, cull tuberculosis-positive cattle and diseased cattle lungs or lymph nodes in slaughterhouses, store the diseased materials at -20℃, and send them to the monitoring room of China Animal Health and Epidemiology Center for testing regularly (no less than 10 samples per province every year).
(4) Undertaking unit. China Center for Animal Health and Epidemiology, Xinjiang Academy of Animal Husbandry and the relevant provincial animal disease prevention and control centers have formulated specific work plans and jointly implemented them.
(5) Investigation of schistosomiasis
Shanghai Sub-center should continue to carry out epidemiological investigation and monitoring of schistosomiasis at the designated schistosomiasis monitoring points.
Attachment 3:
Work plan of special epidemiological investigation
First, the investigation of clinical application of vaccine
(1) Scope. Highly pathogenic porcine blue ear disease live vaccine, classical strain porcine blue ear disease vaccine, highly pathogenic porcine blue ear disease inactivated vaccine; Classical swine fever spleen drenching vaccine, classical swine fever primary cell vaccine, classical swine fever subculture cell vaccine; Asia I -O bivalent foot-and-mouth disease inactivated vaccine, O foot-and-mouth disease vaccine (including inactivated vaccine and synthetic peptide vaccine).
(2) indicators. Clinical application scope, safety, effectiveness, etc.
(3) scope. ① Classical swine fever vaccine and porcine blue ear disease vaccine: carried out in 11 provinces and regions such as Liaoning, Hebei, Shandong, Henan, Yunnan, Guangxi, Fujian, Jiangxi, Anhui, Hunan and Sichuan; ② Foot-and-mouth disease vaccine: carried out in 14 provinces, autonomous regions and municipalities including Heilongjiang, Liaoning, Xinjiang, Henan, Hebei, Tianjin, Shandong, Anhui, Jiangxi, Fujian, Sichuan, Yunnan, Guizhou and Guangxi.
(4) method. The evaluation of porcine blue ear disease vaccine adopts questionnaire survey and field survey; The evaluation of classical swine fever and foot-and-mouth disease vaccines adopts a combination of questionnaire survey, field investigation and sampling detection. Thirty farms are selected for investigation of each classical swine fever and foot-and-mouth disease vaccine, and a certain number of farms and slaughterhouses are selected for antibody and pathogen monitoring.
(5) Undertaking unit. China Animal Health and Epidemiology Center and relevant provincial animal disease prevention and control institutions jointly implemented.
II. Investigation on the cost of prevention and control of highly pathogenic avian influenza
(1) purpose. Through the sampling survey on the cost of prevention and control of highly pathogenic avian influenza since 2004, this paper makes a retrospective evaluation and economic analysis and evaluation on the prevention and control policy of combining immunization with culling, and provides decision-making consultation on the implementation effect of prevention and control policy.
(2) scope. In Shandong, Henan, Guangxi, Jiangsu, Liaoning, Sichuan and other six provinces, according to the poultry feeding quantity (density), production mode and the principle of regional representation, two counties in each province were selected for sampling investigation.
(3) method. By means of questionnaire survey and on-the-spot investigation and interview, the prevention and control of local avian influenza and the occurrence of related costs (immunization, surveillance, emergency response, etc.) since 2004 were understood.
(4) Undertaking unit. China Center for Animal Health and Epidemiology jointly implemented with animal epidemic control institutions in relevant provinces.
Investigation on risk factors of mycoplasma bovis pneumonia
(1) purpose. Through investigation and monitoring activities, the risk factors leading to the occurrence and spread of mycoplasma pneumonia were analyzed, and the countermeasures were put forward.
(2) scope. The survey was conducted in 11 provinces including Shandong, Sichuan, Jilin, Henan, Guangdong, Hunan, Hubei, Jiangxi, Anhui, Fujian and Chongqing. When necessary, the investigation scope extends to other provinces where live cattle are transferred in and out.
(3) method. By means of on-the-spot investigation, sampling inspection and retrospective investigation, the investigation was carried out in farms (households), trading markets and slaughterhouses to master the carrier situation of mycoplasma pneumonia in healthy cattle and the risk factors in circulation and transportation.
(4) Undertaking unit. It is jointly implemented by China Animal Health and Epidemiology Center, Harbin Sub-center, Huazhong Agricultural University, animal disease prevention and control institutions and animal health supervision institutions in relevant provinces.
4. Epidemiological investigation of echinococcosis in livestock
(1) purpose. To understand the infection situation, risk factors and prevention and control effect of echinococcosis in livestock in western pastoral areas.
(2) scope. In Qinghai, Xinjiang, Inner Mongolia and Ningxia, two counties with severe epidemic situation and one county with mild epidemic situation were selected to investigate and sample cattle and sheep (intermediate hosts) and dogs (definitive host).
(3) method. Questionnaire survey, on-site sampling survey and laboratory testing were used to investigate the infection and risk factors of echinococcosis in cattle, sheep and dogs (the specific investigation plan shall be formulated separately).
(4) Undertaking unit. China Center for Animal Health and Epidemiology, Xinjiang Academy of Animal Husbandry and relevant provincial animal disease prevention and control centers jointly implemented.
5. Epidemiological investigation of yak brucellosis
(1) purpose. To understand the distribution, brucellosis infection and risk factors of yak in some western provinces.
(2) scope. In Gansu, Qinghai, Xizang, Sichuan and other four provinces and Xinjiang Production and Construction Corps, three national animal epidemic monitoring and reporting stations or border monitoring and reporting stations with large yak breeding were selected to carry out yak brucellosis investigation.
(3) Undertaking unit. China Center for Animal Health and Epidemiology is jointly implemented by relevant provinces and Xinjiang Production and Construction Corps Animal Disease Prevention and Control Center.
VI. Epidemiological investigation of rabies
(1) purpose. To understand the distribution of domestic dogs and stray dogs, master the immunization status, prevention and control effect and epidemic risk factors of rabies vaccine, and analyze the main problems existing in the prevention and control of rabies.
(2) Scope and method. In Guangdong, Guangxi, Guizhou, Yunnan, Shandong, Inner Mongolia, Beijing, Shanghai and other eight provinces, each province selects provincial capital cities, two prefecture-level cities and two national animal epidemic monitoring stations (border animal epidemic monitoring stations) as investigation points, and randomly selects a certain number of communities, pet hospitals and dog breeders to conduct on-the-spot investigations and conduct sampling tests when necessary.
(3) Undertaking unit. China Center for Animal Health and Epidemiology is jointly implemented by relevant provincial animal disease prevention and control institutions.