上海千花贵族宝贝

　　Under the background that the world economy is facing difficulties, it is particularly important to give full play to its own advantages for the sustainable development of China’s economy. China has formulated scientific and effective policies to promote high-quality development and continuously achieve new results, which is important for the world economy.

　　At present, influenced by multiple factors, the downward pressure on the world economy has increased. In this context, it is more important for China’s economy to show its strong resilience. With the optimization and adjustment of epidemic prevention and control policies, China’s economic and social vitality has been continuously restored, which will provide more powerful kinetic energy for world economic recovery.

　　In recent years, the achievements of high-quality economic development in China are constantly emerging, and the vigorous development of high-tech industries is an example. In 2022, the added value of high-tech manufacturing industry above designated size in China increased by 7.4% over the previous year, and the investment in high-tech manufacturing industry and high-tech service industry increased by 22.2% and 12.1% respectively. With the continuous promotion of reform and opening up, the in-depth implementation of the innovation-driven development strategy and the continuous improvement of the business environment, the new kinetic energy of China’s economic growth will continue to grow and its economic potential is expected to be further released.

　　The COVID-19 epidemic has had many negative effects on international trade, but China has quickly adapted to the new changes in the global economic and trade situation. In 2022, the scale of China’s foreign trade reached a new record high, and the total value of goods import and export exceeded 40 trillion yuan, reaching 42.07 trillion yuan, an increase of 7.7%. China’s foreign trade scale continues to expand, which fully reflects China’s important position in the global industrial chain supply chain. In the future, by further deepening international economic and trade cooperation, China will play a more important role in promoting the global economic cycle and helping the world economic growth.

　　The rapid development of digital economy in China has become a new bright spot of economic growth. Cross-border e-commerce in China has developed vigorously, establishing world-class storage capacity, diversified logistics and transportation channels and efficient logistics and transportation management system, fully demonstrating the vitality of China’s digital economy. China has established a good digital ecosystem, which has made important contributions to the development of global digital economy.

　　Since last year, developed countries have adopted radical monetary policies to curb the high inflation rate, which has intensified the volatility of global financial markets and increased the uncertainty of world economic recovery. Compared with other major economies, China has more macro-policy space. China is implementing a proactive fiscal policy and a prudent monetary policy, and is striving to strengthen the coordination of various policies, which will help China effectively meet the challenges faced by economic development.

　　China has obvious advantages in economic and social development. Under the background that the world economy is facing difficulties, it is particularly important to give full play to its own advantages for the sustainable development of China’s economy. China has formulated scientific and effective policies to promote high-quality development and continuously achieve new results, which is of great benefit to the world economy.

　　(The author is the Acting Director of the Department of World Economy and International Economic Relations, Russian State University of Management)

Even if the world is brilliant, Miss Teresa Teng is hard to describe and draw.

To say that she is beautiful, the word beauty will make you feel ashamed;

Say she is sweet and soft, she is stronger than any man in this world;

She is a once-in-a-century singing genius, and a super idol in history.

And the best person in the world.

Brigitte Lin even said, "I don’t mind if my boyfriend moves on with Teresa Teng."

Teresa Teng was born in the door.

Father Deng Shu finally got a daughter, Teresa Teng, after winning three sons in a row.

Although the Deng family is poor, their lives are very accented.

Deng Shu loves to sing Peking Opera, and his favorite thing is to entertain himself with his youngest daughter.

When little teresa teng opens his mouth, even the dragonfly will forget to fly.

She went on stage at the age of 6 and won the Huangmei tune singing contest at the age of 10.

In middle school, the school opposed her to participate in the performance, which was considered to be corrupt.

Deng Shu said that he could not understand, and in a rage he took his daughter out of school.

So Teresa Teng, who was only 14 years old, officially signed a contract with a record company and became a professional singer.

At the age of 26, he was already popular in Asia.

However, the limelight is strong, but it has avoided going abroad because of the storm.

When I was most confused and depressed, I met Jackie Chan who was filming abroad.

At that time, Jackie Chan, 25, was still a new movie star.

The humble Beowulf is totally incompatible with the gentle and generous Teresa Teng.

However, Teresa Teng was unusually kind to him. He was late for appointments and rude, and everyone was willing to accommodate him.

Because feelings for Teresa Teng, really like life-

At that time, she had lost two prospective fiance.

Zhu Jian, her fellow countryman, was born in a noble family.

At the age of 20, people who ask for relatives step on the threshold, while teenagers are unmoved.

Because he already has a girl in his heart-

Teresa Teng, who is beautiful and can sing.

From the point of view of matching families, they are not worthy.

Fortunately, Zhu Jiaer was open-minded enough. They accepted Teresa Teng and his son’s efforts to help his girlfriend.

With the help of Zhu Jian, Teresa Teng filmed Jingjing and sang I Laugh at the sight of you.

Also took a step to Hong Kong …

Their feelings are also growing day by day, to the point of talking about marriage.

However, one day in July, 1972, Teresa Teng waited for a farewell reunion with her boyfriend, but waited for the news of the plane crash.

She was only 19 years old that year.

For many years, she couldn’t get over this emotional injury.

Until a man named Lin Zhenfa, with continuous and appropriate tenderness, slowly moved the ice in her heart.

In 1971, Teresa Teng was invited to perform in Kuala Lumpur.

Lin Zhenfa, the chairman of Great East Asia Paper, covered the first three rows.

Teresa Teng sang for 45 days, and he kept it for 45 days.

Mr. Lin is five years older than Teresa Teng, enthusiastic, cheerful, spoony and rich.

If Teresa Teng hadn’t gone abroad to develop, they might have got married.

In 1974, Tamaki of Polaroid Records invited her to Japan:

Foreign countries are the second largest music market in the world, which is more important than Southeast Asia.

And he, Zhou Muren, will definitely make her famous within one year.

Three transgressions, Teresa Teng finally tempted.

Six months later, she really won the foreign newcomer award with her single "Airport".

Since then, I have been busier and have little time to meet Mr. Lin.

One night in 1978, Teresa Teng received an urgent message:

Andy Lin had a heart attack and was in critical condition.

But when she arrived at the airport in a low-paying job, she opened the Sing Tao Daily on the plane that day …

I actually saw the news that the man who loved her deeply had left.

Pain of bone erosion.

Six years, twice-

So, Teresa Teng may feel that there is no room for a gentle man in her life.

Jackie Chan’s generosity may be her destiny takes a hand.

But he’s such a jerk!

A few years later, Jackie Chan explained his various rude behaviors in the past: "She is so good that I am useless."

Teresa Teng is generous, but he never gives in.

Even if this person is Jackie Chan, who is quite moved by her.

Or Guo Kongcheng, who wants to spend the rest of her life when she is 30 years old.

In 1981, after Teresa Teng and Guo Kongcheng got engaged, they even decided to quit the entertainment circle.

However, before the wedding banquet, I met my parents once, and things suddenly reversed.

This parent is Guo Kongcheng’s grandmother.

It’s not that I don’t like Teresa Teng-no one doesn’t like a girl like her.

I don’t like her identity-a female star.

Grandmother’s opinion can be respected, but it won’t be a decision.

But the Guo family is different. Guo Kongcheng’s father, Guo Henian, is filial and obedient-

Including which grandson to choose as an heir.

In the face of the grandson’s request, the old-school rich ladies reluctantly agreed, but put forward three conditions for Teresa Teng:

Provide detailed personal information;

Stop all performing arts related to singing and concentrate on being a good wife at home;

Cut off contacts with the entertainment industry from now on, and draw a line with all male friends.

Upon hearing this, Teresa Teng burst into tears.

She knows the rules.

Giving up voluntarily is her sincerity to marriage.

But if this is the condition for marrying into the "Guo family", it is equivalent to recognizing that your work is not decent.

But that’s her pride!

At that time, she had set a record of five albums and won the "Platinum Record" in Hong Kong.

Singing for 7 consecutive times on the Lee stage, breaking the record of consecutive performances of Chinese concerts;

It is also the first Chinese singer invited to perform at the Lincoln Center in new york abroad …

She is Teresa Teng, a proud woman in Chinese music.

And the man who was born in the family of six sugar kings in the world and established a huge Shangri-La hotel system-

She looks so powerful and says she loves her, but her self-esteem is trampled underfoot.

What she wants is love, not the daughter-in-law of the sugar kings.

Later, Guo Kongcheng married a foreign girl, Yumiko.

It is said that he is a fan of Teresa Teng.

It is said that her side face is very much like Teresa Teng when she first debuted.

And Teresa Teng, who has never been short of blood, has resolutely turned around.

Jonathan Lee said that many people are "miracles" and only Teresa Teng can be a "legend".

In 1983, it was even more legendary:

In July, the album "Light Love" was released, which is also the first album in Chinese pop music to compose music with ancient poems.

After that, there was Jay Chou, and there were all kinds of Chinese styles;

In July, with a cumulative record sales of 5 million, it set a record for the record sales of Chinese singers;

In July, she became the first female singer to sing in Hung Hom Gymnasium in Hong Kong, and the first Chinese female singer to hold a multi-site tour.

And set a new record for the audience and box office of Chinese concerts …

In January, 1984, the famous "One Billion Applause" concert tour was held.

At this point, her reputation has been unsurpassed in the Chinese-speaking world.

Where there are Chinese, there are Teresa Teng’s "songs".

At the same time, Teresa Teng also restarted the foreign contract that it had declined before because it planned to get married.

Because of her, the arrogant foreign music scene was crushed by Chinese singers for the first time and only time-

In the 80′ s, when superstars came forth in great numbers.

She keeps refreshing the historical records of major foreign music charts:

The first singer to win the championship for two consecutive years in the national cable broadcasting awards;

A record three times in a row "foreign cable awards" and "national cable broadcasting awards" double champion.

A number of singles have become the annual champions of the total number of karaoke songs sung abroad …

She is even called "Hibari Misora of China".

Every time I go abroad, from the general manager, the company will go to they nest and wait for the driver at the airport.

And her influence, has rushed out of Asia, to the world:

In 1983, she became the first oriental female singer to sign a contract to hold a solo concert at Caesar Palace in Las Vegas.

In 1986, she was selected as "Seven Female Singers in the World" and "Ten Most Popular Female Singers in the World" by Time magazine, becoming the only Asian singer who won two honors at the same time.

Her concert, but also opened all over the world, sweeping the world:

Teresa Teng is a genius of music and language-

She can sing in Cantonese, Minnan and Japanese, English and Malay skillfully.

The charm of the stage is even harder to find in the world-

Cute and cute …

Behave in all manner …

But salt can be salty …

Even wearing a miniskirt with a full back, or singing rock and roll with heavy makeup, it is as pure as an elf.

But no genius can stop the erosion of disease.

In the autumn of 1989, Teresa Teng lived in Paris for a long time for illness.

This romantic city is destined to be her last emotional post.

While recording the album "The Conditions of Tears" in Paris, she met 23-year-old foreign photographer Paul.

Love at first sight, like a little girl in love.

She took the initiative to talk to him and asked him to shoot the cover of the record, and finally kept all these photos as private and refused to show them to others.

They are really in love. She dotes on him and will do anything.

In 1990, Brigitte Lin traveled to Paris and spent a few days with Teresa Teng.

In her eyes, Teresa Teng lived in her dream apartment and was romantic and funny.

And amazingly generous—

The tip for the waiter will never be less than 100 francs.

She is a princess of music, but she is extremely kind to everyone.

Yes, Paul, especially.

Even when she has an asthma attack, Paul can still smoke in the room.

Teresa Teng once said that when she was a child, she was ill, so she felt guilty when she saw her family worried, and felt that she had caused us trouble.

When she grew up, she always played down her physical condition.

Therefore, Paul and even Teresa Teng’s family don’t think this disease will really kill them.

So, when she left, she had no family, no lover and was alone.

On July 8, 1995, Teresa Teng died in Chiang Mai, a foreign country, due to an asthma attack.

Only 42 years old.

The sudden bad news defeated everyone.

Her producer, akira suzuki Dai, couldn’t get over it for ten years.

In his last years, Teresa Teng always hoped to write new songs according to his own wishes.

However, because he refused to sing the songs arranged by the company before, he was retaliated.

Akira suzuki generation is helpless, and dare not tell Teresa Teng the truth.

I have to coax her every time: I’m doing it …

I’ve been coaxing for a long time, but I haven’t seen the song.

Miss Deng finally got angry like never before, and refused to answer her phone for some days.

After Zhou Muren finally became the head of the company, the new song that Teresa Teng wanted was finally finished.

When Dai akira suzuki happily ran to the company to have a job with the boss, she saw that the floor at her feet was wet with tears.

Ten years later, akira suzuki generation didn’t have the courage to go to the grave of Miss Deng, who had given her countless warmth and sisters.

Listen to her whisper: alas, it’s late.

Then quietly reply: I’m sorry.

Akira suzuki’s generation is still like this, not to mention Paul, who has been with him for five years.

Everyone thinks that Paul doesn’t love Teresa Teng enough.

After Teresa Teng’s unexpected death, he hated him even more-

If he had been around when the disease broke out, maybe Miss Deng was still in the world.

However, an accident is an accident, and love is love.

Teresa Teng left a huge legacy, without him.

If he wants to, with Miss Deng’s doting on him, do you want anything? !

After Teresa Teng left, he lived alone in their old home in Stanley.

Refused to leave and meet people for three years.

So how can you not love? !

I just met Teresa Teng at a young age and was spoiled.

Teresa Teng’s life, want to do three things:

Reading, singing and getting married.

She longed for marriage and stepped into it several times.

But Paul and I never thought about it.

The world thinks that Miss Deng doesn’t particularly love Paul.

Perhaps, the whole world is thinking badly.

When she met him, her physical condition was already very bad.

Even when my father died, I couldn’t go back.

I didn’t talk about marriage with him, maybe I just wanted to leave him a free future.

Miss Deng is such a sweet and careful person.

But write down the biggest regret in the world:

But in just forty years, there is no Teresa Teng on earth.

Since then, rain is also a tear, and snow is also a tear.

If the wind is like a song and the sun is just right …

Miss Deng, and where are you?

　　China Institute of Science and Technology Information released a statistical report on China’s scientific papers today. According to the report, the number of papers in the most influential journals in various disciplines in China ranks first in the world for the first time, and the number of papers in high-level international journals and the number of citations rank first in the world.

　　Journals with the highest impact factors in all disciplines can be regarded as the most influential journals in all disciplines in the world. In 2022, there were 159 high-impact journals in 178 disciplines, and the total number of papers in the most influential journals in various disciplines in 2022 was 54,002. The number of papers published in these journals in China is 16,349, accounting for 30.3% of the world’s total, surpassing the United States to rank first in the world for the first time.

　　Journals with the influence factors and total cited times of each discipline living in the top 10% of the discipline, and with more than 50 academic papers and review articles published each year, are selected as representative scientific journals of various disciplines in the world, and the papers published on them belong to high-level international journals. In 2022, a total of 371 international sci-tech journals were selected as representative sci-tech journals of various disciplines in the world, and 348,600 high-level international journal papers were published. According to the statistical analysis of the first author and the first unit, China has published 93,600 high-level international journal papers, accounting for 26.9% of the world total, and the number of citations is 649,600, ranking first in the world in both the number of papers published and the number of citations.

　　In 2022, there were 16 international journals that were cited more than 100,000 times and had an impact factor of more than 30. In 2022, 28,400 papers were published, among which China published 1,140 academic papers and review articles, ranking second in the world, which was the same as in 2021.

　　(CCTV reporter Zhang Chunling Cao Yuzheng)

Friends, we are really tired of eating melons.Zhang Xiaohan, who is not very reliable, has drawn cartoons again!

This time, she still rushed to the hot search with ambiguous melons. According to her description, a "first-line intellectual actress" who is famous for her urban drama met with a married rich man in a hotel in Hainan, and the rich man also sent the actress high-luxury jewelry worth tens of millions to make her happy …

Regardless of whether this melon is real or not, who will take care of Zhang Xiaohan! Put it directly with a hammer. Stop drawing cartoons! Few of the comic books she drew before have ever come true …

But this netizen is right. People’s curiosity can’t be suppressed. Although we scold Zhang Xiaohan for having no credibility, we still can’t help but look for an "intellectual actress" who can sit in the right place according to the information disclosed.

Some netizens have even started to list the names of qualified actresses, such as Jiang Shuying, Dilraba, Angel, Chen Shu, Song Jia Jr., Sunny, Chen Douling, Wu Jinyan … The appraisal criteria are based on the paparazzi’s phrase "an intellectual actress who is famous for her urban drama".

Among them, Jiang Shuying was listed as the most likely actress by netizens because of too many details.

First of all, Jiang Shuying was really helped by the fire in Nothing But Thirty, and she did play a lot of urban dramas herself. It can be said that when I saw her face, I couldn’t help but think of urban female roles such as Jiang Lai and Wang Manni.

Recently, in Ode to Joy 3, Jiang Shuying still plays an urban white-collar Ye Zhenzhen.

Secondly, Jiang Shuying really went to Hainan recently and had a beautiful photo. In the photo, she has long hair, and the red flower in her ear seems to echo the red flower on the plate in Zhang Xiaohan’s cartoon.

As it happens, Jiang Shuying has also sent several selfies recently, and the jewels in the selfie are particularly eye-catching. Immediately, some netizens said: "Is this the jewelry sent by a wealthy businessman, so it is the show of love?"

However, some netizens immediately clarified that they searched for the same model in Jiang Shuying’s selfie. The bracelets and watches are more expensive, but as an actress in Jiang Shuying’s coffee spot, she can afford them. The necklace is only a niche brand with more than 1,000 pieces, which can’t reach the level of "ten million yuan jewelry" at all.

Jiang Shuying and his studio also denied this speechless rumor., the tone is full of helplessness:"I can be talked about, but I can’t be framed."

Then netizens found out that,The characters of wealthy businessmen and wives in cartoons seem to be very similar to those of Yu Dong, president of Bona Film, and his wife Jin Qiaoqiao., just Jin Qiaoqiao also dyed red hair.

After reading the so-called "evidence" dug up by these netizens, my little sister is completely speechless, and everyone’s ability to learn from the melon is really getting better and better!

Then Jin Qiaoqiao sent a message to respond to this matter:"Rumors stop at the wise! Watch more movies when you have time. "

Later, Jin Qiaoqiao replied to the comments of netizens in the comment area. In the face of the "persuasion" of netizens, my sister said that she was too speechless:"Can you don’t believe those false news that are fabricated and maliciously slandered on the Internet! It’s all fake! Fake! Fake! " "This netizen? Can you have a little brain? "

There are even netizens who call Jin Qiaoqiao the "little three" of Yu Dong, and Jin Qiaoqiao is so angry that he directly returns.: "Who are you talking about? Spread rumors? ! If you don’t get it, you have to take a lawsuit! "

Here, my little sister wants to get a word in,Jin Qiaoqiao clarified the "mistress" as early as 2014.Yu Dong ended his first marriage in 2010, and he and Jin Qiaoqiao only met in 2012, so there is no such thing as "mistress intervening".

Then Jin Qiaoqiao called Zhang Xiaohan, saying that he was also curious about who the three people in his cartoon were, and had to say that Jin Qiaoqiao was somewhat domineering!

Speaking of Jin Qiaoqiao, I believe that everyone’s first impression of her is stillThe charming and charming peacock princess in the 98 edition of The Journey to the WestOk! It is this role that opened her up.The road of "princess professional household".

The second princess in the East China Sea in "Pig Eight Rings in Spring" is also unforgettable, and Jin Qiaoqiao’s delicate, expensive and sweet appearance is really very suitable for playing the princess.

Princess Yuzhen in "The Secret History of Yang Guifei" is even more compassionate. Some netizens even commented that she is very "Guanyin" and has a kind face and a beautiful face.

Because of her extraordinary and recognizable beauty, Jin Qiaoqiao has been quite successful in her career since she graduated from Nortel, which is enough for most students to envy.

It is said that you can’t have both career and peach blossom, but Jin Qiaoqiao is different, and her peach blossom has never been bad.

No, Jin Qiaoqiao’s first love was vigorous enough. He directly held hands with Wu Qihua, the top student of TVB at that time, and officially announced his love affair. If this were put in today, it would be enough to paralyze the server.

At that time, Jin Qiaoqiao was quite pure and beautiful, and her figure was full of pure desire. She was a little girl with a happy face. Look at this dress, it is not out of date now!

Although Jin Qiaoqiao’s mother thinks that Wu Qihua and Jin Qiaoqiao are too different in age and somewhat introverted, she thinks that her daughter will not be happy to live with him.

But when the two were in the thick of love, they couldn’t listen to their parents’ thoughts at all.Wu Qihua even bought a mansion in Shanghai and gave it to Jin Qiaoqiao in the name of "wedding room"It is said that it cost 1.6 million, which was 1.6 million in 2003.

The good times didn’t last long, and the two finally broke up.After all, Wu Qihua is a "playboy" with too much romantic history, and it is really difficult to get results in falling in love with him.

Later, Jin Qiaoqiao has been caught in various scandals, but there has been no "positive fate".

For example, Jin Qiaoqiao, the unspoken rule of Zhang Guoli, was also caught by Deng Jie (although it seems that there is no real hammer at all now, it is just an empty talk and a visual sense) ↓

Some netizens broke the news that they had picked up Jin Qiaoqiao’s mobile phone, saying that Jin Qiaoqiao had received an ambiguous text message from a wealthy businessman who wanted to pay for her dinner date. The text message boasted:"We are not short of money, what price, Miss Jin can say. Whatever you want, we will never make a counter-offer. "

It’s not a scandal, can only say that the entertainment circle at that time was really in hot water …

Jin Qiaoqiao’s second love affair was with Yu Dong, CEO of Bona Film, and they went straight to the marriage hall. Jin Qiaoqiao also gave birth to a son and a daughter for Yu Dong.

I mean, I’m really principled, and I don’t talk much about love, either talking about being popular or talking about movie mogul.

After marrying the president, Jin Qiaoqiao is almost in a state of retirement. She has been working as a full-time mother at home, and her personal social accounts also record anecdotes about her children’s growth, and only occasionally does Yu Dong appear.

Netizens are deeply touched by this.In the past, the goddess became a child nanny after marrying into a rich family, or was she a "widowed baby"!

E-mail flipped through Jin Qiaoqiao’s account and found that there were not many children’s fathers.

Either take your children out with your parents ↓

Or take two dolls to the playground by yourself.

Recently, however, some netizens ran into Jin Qiaoqiao and Yu Dong to take the children to Universal Studios. My son took his mother’s hand and Yu Dong touched his son’s head while listening to the voice. The picture was quite warm. It seems that they were very happy, and netizens were also worried about it.

Although Jin Qiaoqiao has been a stay-at-home housewife for many years, it seems that her life is empty and her career is barren, but at least she is also a serious "Bona boss".

It’s up to her to hold a birthday party, and almost half of the big coffee in the entertainment circle came to celebrate her birthday., Jason Wu, Iola, Jet Li, Tung shing Yee, Xiang Huaqiang, Xiangtai, Zhang Ziyi, Li Xiang, Chiu Man-Cheuk, Pu Cunxin, Fan Ming, Fu Disheng, Ren Jing, Chen Xiao, Huang Yi, Tan Jing, Chen Xuedong … How many female stars can do this in-plane entertainment?

Jin Qiaoqiao had nothing to do but open a hot pot restaurant to kill time. Stars such as Yao Chen, Jerry Lee and Lin Yongjian rushed to call her new store, and her contacts were quite amazing.

Perhaps the family can also be a woman’s career. Although Jin Qiaoqiao has been away from the entertainment circle for many years, who said that it is not a real skill to run the family well? (text/seedling bag)

Mesenchymal Stem Cell (MSC) have unique biological characteristics and therapeutic potential, and are becoming a "new star" in the field of disease research, and the research enthusiasm continues unabated. MSC involves many related researches, such as multiple sclerosis, arthritis, neuropathic pain, intestinal diseases, etc., and is a research hotspot in the field of transplantation and autoimmune diseases.

Statistics on the number of published papers in MSC field from 2014 to 2024, with data from Pubmed.

Mesenchymal stem cells (MSC) are pluripotent stem cells derived from mesoderm with high self-renewal and multi-lineage differentiation potential. They are widely distributed in various tissues of the whole body, with the advantages of easy separation and easy acquisition, and can be differentiated and expanded in vitro.

MSC is an excellent tool for tumor therapy and gene transfer research, functional genomics, drug screening, Qualcomm screening and toxicology. International Association for Cell Therapy (ISCT) defines human MSC as:

Under standard culture conditions, it is adherent growth;

CD105, CD73 and CD90 should be expressed, but CD45, CD34, CD14 or CD11b, CD79α or CD19 and HLA-DR surface markers should not be expressed.

It can differentiate into osteoblasts, chondrocytes and adipocytes in vitro.

Mesenchymal stem cells come from a variety of cells or tissues, such as bone marrow, adipose tissue, peripheral blood, placental tissue, dental pulp and so on. Similarly, MSC can also differentiate into many cell types, such as osteoblasts, chondrocytes, fat cells, muscle cells, nerve cells, stromal cells and so on.

The origin and differentiation of MSC (from references)

It is worth noting that the differentiation potential of mesenchymal stem cells may vary with the source of stem cells, expansion conditions and their culture microenvironment. Three-line differentiation is the focus of MSC culture and amplification. Triple differentiation usually refers to osteogenesis, adipogenesis and chondrogenesis. In order to better understand the triple differentiation of MSC, this paper preliminarily summarizes the general process of triple differentiation of MSC and the identification methods corresponding to some markers.

Osteogenic differentiation

MSC can directionally differentiate into osteoblasts under the stimulation of various cytokines and other physical and chemical environments. Then the osteoblasts further differentiated into osteoblast precursor cells and entered a rapid proliferation period. Osteoblasts synthesize and secrete organic matrix at this stage, forming osteoid (mainly type I collagen), characterized by alkaline phosphatase, which is an early sign of osteoblast differentiation and maturity; Alkaline phosphatase appears blue under the microscope after fixation with blue, while undifferentiated cells have no obvious color.

Mature osteoblasts express ECM calcification-related proteins. Long-term osteogenic induction causes calcium ions to precipitate in the form of calcium salts, forming "bone nodules". Bone nodules can be dyed deep red by alizarin red (alizarin red reacts with calcium to produce a deep red compound), and the strength of osteogenic differentiation can be expressed by the area and depth of the pigment.

Identification of osteogenic differentiation of MSC from different sources

Chondrogenic differentiation

Firstly, MSC gathers into a cluster, and the middle cells in the cluster are transformed into a large and round cell, that is, chondrocyte, through division and differentiation. Chondrocytes produce matrix and fibers (mainly type II collagen), and the expression of type II collagen was observed by immunohistochemistry.

Generally, the differentiation results of chondrocytes were identified by Alyssin Blue. Alisine blue is an alkaline dye, which can combine with nucleic acid in cells to make the nucleus dark blue. At the same time, alisin blue combined with polysaccharides in cartilage matrix, making cartilage cells and matrix light blue.

Identification of chondrogenic differentiation of MSC from different sources

Adipogenic differentiation

There are two stages of adipogenic differentiation of MSC: first, it differentiates into adipose precursor cells, and then it differentiates into adipocytes under the influence of specific stimuli (such as C/EBPs and PPAR-γ).

Cells keep accumulating fat droplets in the cytoplasm and getting bigger. After dyeing with oil red O, it is red under the microscope. Undifferentiated cells have no obvious color.

Identification of chondrogenic differentiation of MSC from different sources

Various factors will affect the differentiation potential. Such as culture environment, growth factors and the existence of other cells, will affect the differentiation process. Specific signal molecules, such as bone morphogenetic protein (BMP) or Wingless related integration site (Wnt), can promote the differentiation of stem cells into bone cells or nerve cells, respectively.

The research on mesenchymal stem cells is so hot that Yiqiao Shenzhou has compiled a detailed MSC operation guide. Protocol is full of dry goods, in addition to the above three-line differentiation identification examples, it also includes how to isolate mesenchymal stem cells, how to subculture and expand them, and how to determine that the expanded cells are mesenchymal stem cells. Welcome to download and learn!

Click on the link above to download the Protocol.

References:

Dragomirka Jovic. A Brief Overview of Global Trends in MSC-Based Cell Therapy. Stem Cell Reviews and Reports, 2022. https://doi.org/10.1007/s12015-022-10369-1

Xing Liang Fan, et al. Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy. Cellular and Molecular Life Sciences, 2020. https://doi.org/10.1007/s00018-020-03454-6

Yu Han, et al. Mesenchymal Stem Cells for Regenerative Medicine. Cells, 2019. doi:10.3390/cells8080886

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Hunan Provincial Bureau of Statistics   Hunan Investigation Corps of National Bureau of Statistics

March 23, 2023

In 2022, in the face of the stormy international environment, arduous and arduous tasks of reform, development and stability, and the overlapping influence of epidemic situation, flood and drought, the whole province adhered to the guidance of Socialism with Chinese characteristics Thought of the Supreme Leader in the new era, took the convening of the 20th Party Congress as the main line, studied, publicized and implemented the spirit of the 20th Party Congress, and earnestly implemented the important requirements of "keeping the epidemic under control, stabilizing the economy and ensuring safe development". Fully implement the strategic positioning and mission of "three highs and four innovations", adhere to the working idea of "steady progress in high and new technologies", do a good job of "two overall plans", keep the overall economic and social situation stable, and make progress in major economic indicators, so as to lay a solid foundation for making a good start in the construction of a modern new Hunan with Chinese characteristics.

First, comprehensive       close

According to the unified accounting results of regional GDP, the annual regional GDP[2] 4,867.04 billion yuan, an increase of 4.5% over the previous year, higher than the national average. Among them, the added value of the primary industry was 460.27 billion yuan, an increase of 3.6%; The added value of the secondary industry was 1,918.26 billion yuan, an increase of 6.1%; The added value of the tertiary industry was 2,488.51 billion yuan, an increase of 3.5%. The per capita GDP was 73,598 yuan, an increase of 4.8%.

The tertiary industrial structure is 9.5: 39.4: 51.1. The industrial added value increased by 6.4% over the previous year, accounting for 30.9% of the regional GDP; The added value of high-tech industries increased by 12.7%, accounting for 24.4% of the regional GDP; The added value of strategic emerging industries increased by 7.5%, accounting for 10.5% of the regional GDP. The contribution rates of the added value of the primary, secondary and tertiary industries to economic growth are 8.2%, 51.3% and 40.5% respectively. Among them, the contribution rate of industry to economic growth is 42.6%, and that of producer services is 23.4%.

Regionally, Changsha-Zhuzhou-Xiangtan area[3]The GDP was 2,028.05 billion yuan, an increase of 4.5% over the previous year; The GDP of southern Hunan was 948.05 billion yuan, an increase of 5.3%; The GDP of western Hunan was 781.62 billion yuan, up by 4.2%. The GDP of Dongting Lake area was 1,109.32 billion yuan, an increase of 4.9%.

Second, agriculture       job

The total output value of agriculture, forestry, animal husbandry and fishery was 816.01 billion yuan, an increase of 3.8% over the previous year. The grain planting area was 4,765.5 thousand hectares, an increase of 7.2 thousand hectares or 0.2%. Among them, the area of summer grain was 112.6 thousand hectares, a decrease of 1.2 thousand hectares or 1.1%; The area of early rice was 1212.8 thousand hectares, a decrease of 6.8 thousand hectares or 0.6%; The area of autumn grain was 3,440.1 thousand hectares, an increase of 15.2 thousand hectares or 0.4%. Among the autumn grain areas, the area of middle rice and late rice in one season is 1481.9 thousand hectares, an increase of 2.7 thousand hectares or 0.2%; The area of double-cropping late rice is 1273.0 thousand hectares, an increase of 0.7 thousand hectares or 0.1%. The annual grain output was 30.18 million tons, a decrease of 563,000 tons and a decrease of 1.8%. Among them, the output of summer grain was 456,000 tons, an increase of 5,000 tons and an increase of 1.0%; The output of early rice was 7.413 million tons, a decrease of 25,000 tons and a decrease of 0.3%. The output of autumn grain was 22.311 million tons, a decrease of 543,000 tons and a decrease of 2.4%.

The annual cotton planting area was 64.6 thousand hectares, an increase of 7.4% over the previous year; The planting area of sugar is 7.6 thousand hectares, an increase of 0.4%; The oil planting area was 1518.2 thousand hectares, an increase of 2.6%. Cotton output was 82,000 tons, an increase of 2.3%; 2.77 million tons of oil, an increase of 5.3%; 195,000 tons of flue-cured tobacco, an increase of 5.8%; 265,000 tons of tea, an increase of 2.6%.

The total output of pigs, cattle, sheep and poultry was 5.773 million tons, an increase of 3.1% over the previous year. Among them, the output of pork was 4.579 million tons, an increase of 3.3%; The beef output was 216,000 tons, an increase of 1.4%; The mutton output was 182,000 tons, an increase of 4.0%; The output of poultry meat was 796,000 tons, an increase of 2.3%. At the end of the year, the number of live pigs was 41.162 million, down 2.0% from the end of last year, among which the number of fertile sows was 3.696 million, up 0.4%; The cattle population was 4.418 million, an increase of 1.5%; The number of sheep was 8.014 million, an increase of 3.4%; There were 363.324 million poultry in cages, down by 3.0%. In the whole year, 62.482 million pigs were slaughtered, an increase of 2.1% over the previous year; 1.831 million cattle were slaughtered, an increase of 1.3%; 11.014 million sheep were slaughtered, an increase of 3.5%; 552.132 million poultry were released, an increase of 2.2%. The output of poultry eggs was 1.175 million tons, down by 0.3%; The milk output was 72,000 tons, an increase of 26.3%; The output of aquatic products was 2.726 million tons, an increase of 2.4%.

232 high-standard farmland construction projects were implemented throughout the year, with a construction area of 4.6 million mu. 2619 water conservancy construction projects were started, with an investment of 56.60 billion yuan, and 240 million cubic meters of earth and stone were completed. 6,995.7 kilometers of rural tourist roads, resource roads and industrial roads were upgraded and transformed. At the end of the year, the total power of agricultural machinery was 67.78 million kilowatts, an increase of 1.5% over the end of the previous year.

III. Industry and Construction Industry

The added value of industrial enterprises above designated size increased by 7.2% over the previous year. Among them, the added value of private enterprises increased by 7.5%, accounting for 69.8% of industries above designated size. High-tech manufacturing[4]The added value increased by 18.0%, accounting for 13.9% of industries above designated size, an increase of 0.9 percentage points over the previous year. equipment manufacturing industry[5]The added value increased by 9.9%, accounting for 31.7% of industries above designated size. The industrial added value of provincial and above industrial parks increased by 8.0%, accounting for 72.5% of industries above designated size, up by 2.7 percentage points over the previous year. The added value of the six high energy-consuming industries increased by 6.6%, accounting for 30.2% of the industries above designated size. Regionally, the added value of industrial enterprises above designated size increased by 8.1% in Changsha, Zhuzhou and Xiangtan, 8.3% in southern Hunan, 5.8% in western Hunan and 7.0% in Dongting Lake.

Among the main products of industrial statistics above designated size in the whole year, rice was 18.509 million tons, down 1.9% from the previous year; Feed was 22.606 million tons, an increase of 6.7%; The processing capacity of crude oil was 8.283 million tons, up by 2.4%; 99.444 million tons of cement, down 6.3%; 30.383 million tons of steel, an increase of 1.9%; Ten kinds of non-ferrous metals were 2.323 million tons, down 3.7%; 30,000 concrete machines, down by 24.5%; 916,000 cars, an increase of 38.2%; The power generation was 165.90 billion kWh, down by 0.6%.

Table 1  Output and growth rate of major industrial products above designated size in 2022[6]

Total profits of industrial enterprises above designated size[7]231.01 billion yuan, up 11.5% over the previous year. In terms of economic types, state-owned enterprises reached 13.26 billion yuan, up by 19.4%; Collective enterprises reached 480 million yuan, an increase of 63.7%; Joint-stock cooperative enterprises reached 400 million yuan, an increase of 62.5%; Joint-stock enterprises reached 195.33 billion yuan, an increase of 11.1%; Foreign investors and businessmen from Hong Kong, Macao and Taiwan invested 14.78 billion yuan, an increase of 8.8%; Other domestic-funded enterprises reached 7.13 billion yuan, up by 10.1%. Among the top five industries with total profits, the manufacturing of chemical raw materials and chemical products was 21.79 billion yuan, an increase of 24.3%; Computer, communication and other electronic equipment manufacturing industry reached 20.79 billion yuan, an increase of 28.7%; Non-metallic mineral products industry was 20.18 billion yuan, down 15.6%; The tobacco products industry was 13.21 billion yuan, an increase of 33.2%; The special equipment manufacturing industry was 12.79 billion yuan, down by 14.2%. The cost per 100 yuan of operating income of industrial enterprises above designated size is 83.26 yuan, and the profit rate of operating income is 4.85%. At the end of the year, the asset-liability ratio of industrial enterprises above designated size was 51.4%.

The added value of the construction industry in the whole year was 417.49 billion yuan, an increase of 5.1% over the previous year. The total profit of general contracting and professional contracting construction enterprises above qualification was 33.27 billion yuan, down by 7.8%. The building construction area was 761.601 million square meters, down by 0.3%. The completed building area was 239.885 million square meters, down by 0.2%.

Fourth, the service industry

The added value of wholesale and retail industry in the whole year was 478.71 billion yuan, an increase of 1.8% over the previous year; The added value of transportation, warehousing and postal services was 169.69 billion yuan, up by 0.6%; The added value of accommodation and catering industry was 95.15 billion yuan, an increase of 2.2%; The added value of the financial industry was 242.15 billion yuan, up by 6.2%; The added value of the real estate industry was 282.20 billion yuan, down by 3.9%; The added value of information transmission, software and information technology services was 115.38 billion yuan, an increase of 15.0%; The added value of leasing and business services was 159.74 billion yuan, up by 4.9%. The annual operating income of service enterprises above designated size increased by 7.8%, and the total profit increased by 7.5%.

The annual turnover of passenger and cargo transportation was 351.16 billion tons kilometers, down 2.7% from the previous year. The turnover of cargo transportation was 295.05 billion tons kilometers, an increase of 1.2%. Among them, the railway turnover was 101.56 billion tons kilometers, an increase of 2.9%; The turnover of highways was 146.50 billion tons kilometers, up by 0.3%. Passenger transport turnover was 78.10 billion person-kilometers, down by 22.9%. Among them, the railway turnover was 53.87 billion person-kilometers, down by 18.5%; Highway turnover was 14.66 billion person-kilometers, down by 25.0%; The turnover of civil aviation was 9.39 billion person-kilometers, down by 39.7%.

At the end of the year, the mileage of highways was 242,400 kilometers, an increase of 0.2% over the end of last year. Among them, the expressway mileage was 7330 kilometers, an increase of 247 kilometers. The operating mileage of railways was 6,078 kilometers, an increase of 2.9%. Among them, the high-speed railway is 2408 kilometers, an increase of 159 kilometers. The number of civilian vehicles was 11.064 million, an increase of 6.9%. Among them, the number of private cars was 10.308 million, an increase of 7.0%. The number of civilian cars was 6.1 million, an increase of 7.5%.

Table 2  In 2022, the total volume of passenger and cargo transportation completed by various modes of transportation and its growth rate

Total business volume of postal industry in the whole year[8]32.82 billion yuan, up 10.9% over the previous year; Total telecom service[9]66.69 billion yuan, an increase of 26.9%. At the end of the year, there were 5.487 million fixed-line users, down 3.5% from the end of the previous year; There were 71.806 million mobile phone users, an increase of 3.4%. By the end of the year, there were 24.751 million Internet broadband users, an increase of 6.5%.

There were 430 million domestic tourists in the whole year, an increase of 1.0% over the previous year; There were 77,000 inbound tourists, an increase of 10.6%. The total tourism revenue was 648.80 billion yuan, down by 0.9%. Among them, domestic tourism revenue was 648.64 billion yuan, down by 0.9%; International tourism revenue reached US$ 20 million, up by 21.8%.

V. Investment in fixed assets

Annual investment in fixed assets (excluding farmers) increased by 6.6% over the previous year. Among them, private investment increased by 8.5%. In terms of economic types, state-owned investment decreased by 7.9% and non-state-owned investment increased by 11.2%. In terms of investment direction, investment in people’s livelihood projects increased by 3.2%, investment in ecological environment increased by 1.9%, investment in infrastructure increased by 8.0%, and investment in high-tech industries increased.[10]The growth rate was 22.4%, and the investment in industrial technological transformation increased by 4.6%. Regionally, investment in Changsha, Zhuzhou and Xiangtan increased by 1.7%, investment in southern Hunan increased by 10.8%, investment in greater western Hunan increased by 7.8%, and investment in Dongting Lake increased by 9.1%.

The investment in real estate development in the whole year was 518.03 billion yuan, down 4.6% from the previous year. Among them, residential investment was 405.30 billion yuan, down 2.7%. The sales area of commercial housing was 67.929 million square meters, down by 26.1%. Among them, the residential sales area was 60.854 million square meters, down by 26.8%. The sales of commercial housing was 431.23 billion yuan, down by 28.6%. Among them, residential sales reached 380.01 billion yuan, down by 29.5%. At the end of the year, the area of commercial housing for sale was 12.213 million square meters, an increase of 750,000 square meters or 6.5% over the end of the previous year.

Table 3  Growth rate of fixed assets investment in 2022

VI. Domestic Trade and Prices

The total retail sales of consumer goods in the whole year was 1,905.07 billion yuan, an increase of 2.4% over the previous year. In terms of business locations, the retail sales of urban consumer goods was 1,646.64 billion yuan, an increase of 2.4%; The retail sales of rural consumer goods reached 258.43 billion yuan, an increase of 2.8%. In terms of consumption types, the retail sales of commodities was 1,675.80 billion yuan, an increase of 2.6%; The catering revenue was 229.26 billion yuan, up by 1.0%. In terms of regions, the total retail sales of social consumer goods in Changsha, Zhuzhou and Xiangtan reached 740.47 billion yuan, up by 2.4%. The total retail sales of social consumer goods in southern Hunan was 386.83 billion yuan, an increase of 2.7%; The total retail sales of social consumer goods in western Hunan was 340.60 billion yuan, an increase of 2.0%; The total retail sales of social consumer goods in Dongting Lake area was 437.17 billion yuan, an increase of 2.6%.

Table 4  Total retail sales of social consumer goods and its growth rate in 2022

The retail sales of wholesale and retail commodities above designated size reached 633.62 billion yuan, an increase of 8.8% over the previous year. By commodity category, the retail sales of grain, oil and food increased by 13.5%, cosmetics decreased by 20.9%, household appliances and audio-visual equipment decreased by 4.9%, Chinese and western medicines increased by 15.4%, communication equipment increased by 15.8%, petroleum and products increased by 15.7%, and automobiles increased by 5.9%. Among green smart goods, the retail sales of wearable smart devices increased by 7.9%, and new energy vehicles increased by 134.1%.

The annual online retail sales of physical goods reached 211.67 billion yuan, up by 14.5% over the previous year, accounting for 11.1% of the total retail sales of social consumer goods.

The annual consumer price rose by 1.8% over the previous year. Among them, cities rose by 1.7% and rural areas rose by 1.9%. The retail price of commodities rose by 3.2%. The ex-factory price of industrial producers rose by 2.0%, and the purchase price of industrial producers rose by 4.8%. Producer prices of agricultural products rose by 3.6%.

Table 5  The fluctuation range of consumer prices in 2022 compared with the previous year.

VII. Foreign Economy

Total annual import and export volume[11]705.82 billion yuan, up 20.2% over the previous year. Among them, exports reached 515.45 billion yuan, up by 25.3%; Imports reached 190.36 billion yuan, an increase of 8.3%. In terms of trade mode, the general trade export was 453.16 billion yuan, an increase of 30.5%; The export of processing trade was 38.57 billion yuan, down 3.4%. Among the key export commodities, mechanical and electrical products were 212.37 billion yuan, an increase of 18.3%; High-tech products reached 55.92 billion yuan, an increase of 12.2%. In terms of production and sales countries (regions), the export to the United States was 72.54 billion yuan, an increase of 2.8%; Exports to Hong Kong, China reached 52.93 billion yuan, up 2.6%; Export to EU[12]50.38 billion yuan, an increase of 7.8%; Exports to ASEAN reached 116.38 billion yuan, an increase of 68.5%; Exports to countries along the "Belt and Road" reached 212.11 billion yuan, an increase of 52.5%; Exports to other RCEP member countries reached 159.76 billion yuan, an increase of 49.0%.

Table 6  Total import and export volume and its growth rate in 2022

The actual use of foreign direct investment in the whole year was 3.53 billion US dollars, an increase of 46.1% over the previous year. Among them, the primary industry was $0.2 billion, down by 41.8%; The secondary industry was $1.17 billion, an increase of 214.8%; The tertiary industry was US$ 2.34 billion, up by 16.0%. One of the world’s top 500 enterprises was newly introduced. In fact, the domestic and foreign funds in place were 1,292.98 billion yuan, an increase of 14.6%. Among them, the primary industry was 67.54 billion yuan, an increase of 3.6%; The secondary industry was 695.96 billion yuan, an increase of 29.9%; The tertiary industry was 529.48 billion yuan, an increase of 0.4%. 1,515 major projects with contracts of more than 200 million yuan (foreign investment of 30 million US dollars) were introduced.

In the whole year, the newly signed contracts for foreign contracted projects amounted to US$ 2.48 billion, with a turnover of US$ 1.76 billion. 5,000 laborers of various types were dispatched. Foreign direct investment increased Chinese contract value by 2.68 billion US dollars, up by 226.4%. The actual amount of foreign direct investment was US$ 1.91 billion, up by 14.8%.

VIII. Finance and finance

The local general public budget revenue in 2001 was 310.18 billion yuan, down 4.6% from the previous year (the same caliber increased by 6.6% after deducting the tax rebate and other factors). Among them, the tax revenue was 200.45 billion yuan, down by 10.8%; Non-tax revenue was 109.73 billion yuan, an increase of 9.2%. Among tax revenue, domestic value-added tax was 54.15 billion yuan, down 31.0%; Enterprise income tax was 23.43 billion yuan, down 13.6%. The general public budget expenditure was 900.53 billion yuan, an increase of 8.2%. Among them, education expenditure was 150.25 billion yuan, an increase of 9.4%; Expenditure on social security and employment was 144.20 billion yuan, an increase of 9.9%; Health expenditure was 82.18 billion yuan, an increase of 11.1%; Expenditure on science and technology was 27.99 billion yuan, an increase of 28.8%; Expenditure on housing security was 22.34 billion yuan, up by 0.5%.

Table 7  Revenue and Expenditure of Local General Public Budget and Its Growth Rate in 2022

At the end of the year, the balance of local and foreign currency deposits of financial institutions was 7,014.19 billion yuan, an increase of 11.5% over the end of the previous year. Among them, the balance of household deposits was 4,131.39 billion yuan, an increase of 16.3%; The balance of deposits of non-financial enterprises was 1,417.47 billion yuan, an increase of 2.6%. The balance of local and foreign currency loans was 6,235.15 billion yuan, up by 11.7%. Among them, the balance of household loans was 2,157.62 billion yuan, an increase of 3.8%; The loan balance of non-financial enterprises and government organizations was 4,049.89 billion yuan, an increase of 15.9%.

Table 8  The balance of local and foreign currency deposits and loans of financial institutions at the end of 2022 and its new increase.

At the end of the year, there were 138 listed companies in the province, and the total direct financing for the whole year was 367.89 billion yuan, down 17.0% from the previous year. At the end of the year, the total market value of A-share listed companies was 1,585.18 billion yuan, down 20.5% from the end of the previous year. At the end of the year, there were 434 business departments of securities companies, a decrease of 5; The annual securities transaction volume was 11,979.11 billion yuan, down by 1.6%. At the end of the year, there were 2 futures companies in the jurisdiction, which was the same as the end of last year; The annual turnover was 5,574.65 billion yuan, down by 21.9%.

In the whole year, the original insurance premium income of insurance companies was 161.37 billion yuan, an increase of 7.0% over the previous year. Among them, life insurance premium income was 81.78 billion yuan, an increase of 9.3%; Health insurance premium income was 32.85 billion yuan, an increase of 0.07%; Personal accident insurance premium income was 3.74 billion yuan, down 8.2%; Property insurance premium income was 43.01 billion yuan, up by 9.9%. The original insurance payment expenditure was 58.08 billion yuan, an increase of 9.8%.

IX. Education, Science and Technology

There were 116 colleges and universities at the end of the year. There are 29,000 graduates of postgraduate education, 449,000 graduates of ordinary higher education, 227,000 graduates of secondary vocational education, 425,000 graduates of ordinary high schools, 847,000 graduates of junior high schools and 903,000 graduates of ordinary primary schools. There were 2.16 million children in the park, down 5.8% from the previous year. Enrolment rate of primary school-age children[13]100%, the gross enrollment rate of high school education[14]94.47%。 There are 10,498 private schools with 2.38 million students. 1.38 billion yuan of national scholarships and grants were granted to college students, and 729,000 college students were assisted. 510 million yuan of state grants for secondary vocational schools were granted, and 514,000 secondary vocational students were assisted. We implemented 10.55 billion yuan of compulsory education guarantee funds and distributed 540 million yuan of state grants to ordinary senior high schools.

Table 9  The number of students enrolled, enrolled and graduated in schools at all levels and their growth rate in 2022

At the end of the year, there were 12 national engineering research centers (engineering laboratories) and 354 provincial engineering research centers (engineering laboratories). There are 42 national and local joint engineering research centers (engineering laboratories). There are 68 enterprise technology centers recognized by the state. There are 14 national engineering technology research centers and 523 provincial engineering technology research centers. There are 19 national key laboratories and 337 provincial key laboratories. During the year, 45,780 technical contracts were signed, with a turnover of 254.46 billion yuan. 1,086 scientific and technological achievements were registered. The number of patents granted was 92,916, down 6.1% from the previous year. Among them, the number of invention patents granted was 20423, an increase of 23.3%. The number of patents granted by industrial and mining enterprises, universities and scientific research units is 60706, 12763 and 836 respectively.

At the end of the year, there were 2135 inspection and testing institutions. Among them, there are 25 national product quality supervision and inspection centers. There are 104 legal metrological verification institutions. There are 2,005 special equipment production units and 493,000 special equipment. The qualified rate of supervision and spot check of key industrial products is 87.3%. Participated in the formulation of 6 international standards, 224 national standards and 284 local standards. 3,219 maps were published publicly, with 739,000 daily map users visiting and 730,000 geospatial data achievements provided.

X. Culture, Health and Sports

By the end of the year, there were 675 performing arts groups, 146 mass art museums and cultural centers, 144 public libraries and 162 museums and memorial halls. There are 108 radio and television stations (broadcasters). There are 5.85 million cable TV users. The comprehensive population coverage rate of broadcasting is 99.42%, and that of television is 99.76%. There are 137 national intangible cultural heritage protection catalogues and 410 provincial intangible cultural heritage protection catalogues. There are 11,608 kinds of books, 253 kinds of periodicals and 44 kinds of newspapers. The total print runs of books, periodicals and newspapers are 550 million, 90 million and 620 million respectively.

At the end of the year, there were 55,329 health institutions. Among them, there are 1,733 hospitals, 137 maternal and child health centers (institutes and stations), 70 specialized disease prevention hospitals (institutes and stations), 2,085 township health centers, 987 community health service centers (stations), 12,726 clinics, health centers and medical offices, and 36,128 village clinics. There were 517,000 health technicians, an increase of 2.1% over the previous year. Among them, there are 197,000 practicing doctors and assistant practicing doctors and 244,000 registered nurses. The hospital has 399,000 beds, an increase of 2.4%; Township hospitals have 109,000 beds, an increase of 2.6%.

There are 25.501 million people who regularly participate in physical exercise in the province, and 1178 national fitness programs have been carried out. There are 1100 new administrative villages for farmers’ physical fitness projects. Won 43 national championships throughout the year. There are 173,677 sports venues. Among them, there are 287 gymnasiums, 7,293 sports grounds, 1,200 swimming pools and 7,666 training rooms.

XI. Population, Residents’ Income, Consumption and Social Security

At the end of the year, the resident population of the province was 66.04 million. Among them, the urban population was 39.83 million, and the urbanization rate was 60.31%, an increase of 0.6 percentage points over the end of last year. The annual birth population was 412,000, with a birth rate of 6.23 ‰; The death population was 565,000, with a mortality rate of 8.54 ‰; The natural population growth rate is -2.31‰. The proportion of the population aged 0-15 (including those under 16) to the resident population was 19.52%, down by 0.67 percentage points; The proportion of people aged 16-59 (including those under 60) was 59.65%, down by 0.38 percentage points; The proportion of people aged 60 and over was 20.84%, an increase of 1.05 percentage points.

Table 10  Number and composition of permanent residents at the end of 2022

In the whole year, the per capita disposable income of residents in the province was 34,036 yuan, an increase of 6.4% over the previous year; The median per capita disposable income of residents in the province was 27,400 yuan, an increase of 6.1%. According to the place of permanent residence, the per capita disposable income of urban residents was 47,301 yuan, an increase of 5.4%; The median per capita disposable income of urban residents was 42,432 yuan, an increase of 5.6%. The per capita disposable income of rural residents was 19,546 yuan, an increase of 6.8%; The median per capita disposable income of rural residents was 17,583 yuan, an increase of 6.6%. The income ratio of urban and rural residents decreased from 2.45 in the previous year to 2.42. In terms of regions, the per capita disposable income of all residents in Changsha, Zhuzhou and Xiangtan is 51,802 yuan, an increase of 5.9%; The per capita disposable income of all residents in southern Hunan is 31,500 yuan, an increase of 6.6%; The per capita disposable income of all residents in western Hunan was 23,611 yuan, an increase of 6.4%; The per capita disposable income of all residents in Dongting Lake area was 31,070 yuan, an increase of 6.5%. Poverty alleviation county[16]The per capita disposable income of rural residents was 14,714 yuan, an increase of 8.7%.

The per capita consumption expenditure of residents in the province was 24,083 yuan, an increase of 5.6% over the previous year. According to the permanent residence, the per capita consumption expenditure of urban residents was 29,580 yuan, an increase of 4.5%; The per capita consumption expenditure of rural residents was 18,078 yuan, an increase of 6.6%.

In the whole year, 737,000 people were newly employed in cities and towns. At the end of the year, the number of people participating in the basic old-age insurance for urban and rural residents was 32.415 million, down 0.6% from the end of the previous year. The number of people participating in the basic old-age insurance for urban workers was 18.929 million, an increase of 2.3%. Among them, there are 13.523 million employees and 5.406 million retirees. The number of people participating in the basic medical insurance for urban and rural residents was 54.705 million, and the number of people participating in the basic medical insurance for urban workers was 10.527 million. The number of people participating in unemployment insurance was 7.239 million, an increase of 5.3%. The number of employees participating in industrial injury insurance was 8.943 million. The number of employees participating in maternity insurance was 7.236 million. At the end of the year, the number of employees receiving unemployment insurance was 148,000.

345,000 urban residents received the government’s minimum living guarantee, and 1.94 billion yuan of minimum living guarantee funds were distributed; 1.421 million rural residents received the government’s minimum living guarantee, and the minimum living guarantee fund was 5 billion yuan. At the end of the year, 270,000 beds were provided for residential civil administration institutions, and 120,000 people were adopted. Among them, there are 253,000 beds in the old-age care institutions and 112,000 people in the old-age care institutions. There are 32,000 community service institutions and facilities. In the whole year, we sold 5.85 billion yuan of social welfare lottery tickets and raised 1.87 billion yuan of welfare lottery funds. Successfully completed 10 key livelihood issues. Among them, 1,500 old urban communities were rebuilt, with an additional water storage capacity of 47.945 million cubic meters, and 339,000 pregnant women were screened free of charge.

XII. Resources, Environment and Safety in Production

147 kinds of minerals have been discovered and 113 kinds of minerals have been proved in the province. Among them, there are 7 kinds of energy minerals, 39 kinds of metal minerals, 65 kinds of non-metal minerals and 2 kinds of water and gas minerals. Five geological exploration projects (including continuation projects) (including provincial financial investment projects only) were funded by the government, and 11 large and medium-sized mineral areas were newly discovered.

In the whole year, the proportion of water quality sections meeting or better than Class III standards was 97.4%, an increase of 1.3 percentage points over the previous year. The air quality of eight municipal cities reached the second-class standard. The harmless treatment rate of municipal solid waste in the city is 100%. There are 53 nature reserves at or above the provincial level, covering an area of 906,000 hectares. Among them, 23 are national and 30 are provincial. There are 2 world geoparks and 14 national geoparks. The afforestation area was 331,000 hectares.

The comprehensive energy consumption of industrial enterprises above designated size decreased by 0.9% over the previous year. Among them, the comprehensive energy consumption of six high-energy-consuming industries decreased by 0.9%.

In the whole year, there were 1330 production and operation safety accidents, and 1428 people died in production and operation safety accidents. There were 0.03 deaths in accidents with GDP of 100 million yuan, and 0.005 deaths in millions of tons of coal mines. The number of deaths per 10,000 vehicles in road traffic accidents was 2.59, a decrease of 0.75 over the previous year.

 

Notes:

[1] The data in this bulletin are all preliminary statistics, and some data are not equal to the total of sub-items due to rounding.

[2] The absolute figures of regional GDP, added value of tertiary industries and related industries and per capita regional GDP are calculated at current prices, and the growth rate is calculated at constant prices.

[3] Changsha-Zhuzhou-Xiangtan region refers to Changsha, Zhuzhou and Xiangtan, southern Hunan refers to Hengyang, Chenzhou and Yongzhou, western Hunan refers to Shaoyang, Zhangjiajie, Huaihua, Loudi and Xiangxi Autonomous Prefecture, and Dongting Lake refers to Yueyang, Changde and Yiyang.

[4] High-tech manufacturing includes pharmaceutical manufacturing, aviation, spacecraft and equipment manufacturing, electronic and communication equipment manufacturing, computer and office equipment manufacturing, medical equipment and instrumentation manufacturing, and information chemicals manufacturing.

[5] Equipment manufacturing industry includes metal products industry, general equipment manufacturing industry, special equipment manufacturing industry, automobile manufacturing industry, railway, ship, aerospace and other transportation equipment manufacturing industry, electrical machinery and equipment manufacturing industry, computer, communication and other electronic equipment manufacturing industry, and instrument manufacturing industry.

[6] The output data of some products in 2021 were verified and adjusted, and the output growth rate in 2022 was calculated according to comparable caliber.

[7] Due to the changes in the scope of investigation stipulated in the statistical investigation system, statistical law enforcement, elimination of duplicate data and other factors, the growth rate and changes of financial indicators of industrial enterprises above designated size in 2022 are calculated according to comparable caliber.

[8] The total business volume of the postal industry is calculated at constant prices in 2020.

[9] The total telecom business is calculated at the constant price of last year.

[10] High-tech industry investment includes six categories of high-tech manufacturing investment and information services, e-commerce services, inspection and testing services, high-tech services in professional and technical services, R&D and design services, scientific and technological achievements transformation services, intellectual property rights and related legal services, environmental monitoring and governance services and other high-tech services, including pharmaceutical manufacturing, aviation, spacecraft and equipment manufacturing, electronic and communication equipment manufacturing, computer and office equipment manufacturing, medical equipment and instrumentation manufacturing.

[11] According to relevant regulations, foreign trade is denominated in RMB.

[12] The import and export amount of goods to the EU does not include the data of Britain, and the growth rate is calculated according to the comparable caliber.

[13] The enrollment rate of primary school-age children refers to the percentage of school-age children who have entered primary school within the scope of investigation to the total number of school-age children inside and outside the school.

[14] The gross enrollment rate of high school education mainly reflects the coverage of high school education, which means that the total number of students in high school accounts for the percentage of the school-age population aged 15-17.

[15] By the end of 2022, there were 11.99 million people aged 0-14 (including those under the age of 15) and 40.29 million people aged 15-59 (including those under the age of 60).

[16] Poverty-stricken counties in Hunan Province, that is, the original poverty-stricken areas in Hunan, including the original concentrated contiguous poverty-stricken areas and the original national poverty alleviation and development key counties outside the area, have a total of 40 counties.

Source:

The financial data in this bulletin comes from the Provincial Department of Finance; Railway transportation and mileage data are from China Railway Guangzhou Bureau Group Co., Ltd., China Railway Nanning Bureau Group Co., Ltd., China Railway Nanchang Bureau Group Co., Ltd., China Railway Wuhan Group Co., Ltd. and Shichang Railway Co., Ltd.; The data of highway transportation, waterway transportation and highway mileage come from the Provincial Department of Transportation; The data of civil aviation transportation comes from Provincial Airport Management Group Co., Ltd. and China Southern Airlines Co., Ltd. Hunan Branch; Pipeline transportation data come from Changling Branch of China Petrochemical Co., Ltd., Changling Branch of China Petrochemical Group Asset Management Co., Ltd., Baling Petrochemical Branch of China Petrochemical Group Asset Management Co., Ltd., Hunan Oil Transportation Branch of Huazhong Branch of National Petroleum and Natural Gas Pipeline Network Group Co., Ltd., Changsha Xinao Gas Co., Ltd., Changsha China Resources Gas Co., Ltd., Xiangtan Xinao Gas Co., Ltd., Changde PetroChina Kunlun Gas Co., Ltd., Loudi China Resources Gas Co., Ltd., etc. Car ownership data comes from the provincial public security department; The data of telecom business volume, mobile phone users, fixed phone users and Internet broadband users come from the Provincial Communications Administration. The postal service data comes from the provincial postal administration; Deposit and loan data come from Changsha Central Branch of China People’s Bank; The data of listed companies come from the provincial local financial supervision administration; Securities and futures data come from Hunan Supervision Bureau of China Securities Regulatory Commission; The data of insurance industry comes from Hunan Supervision Bureau of Bank of China Insurance Regulatory Commission; Education data comes from the Provincial Department of Education; Science and technology data comes from the Provincial Science and Technology Department;Patent, quality inspection and industry standard data come from the Provincial Market Supervision Administration; Surveying and mapping, mineral resources data from the Provincial Department of Natural Resources; Data on the protection of art performance groups, museums, public libraries, cultural centers and intangible cultural heritage come from the Provincial Department of Culture and Tourism. Radio and television data come from the Provincial Radio and Television Bureau; The data of newspapers, periodicals and books come from the Propaganda Department of the Provincial Party Committee; Health data comes from the Provincial Health and Wellness Committee; Sports data comes from the provincial sports bureau; The data of new employment, social insurance and vocational skills training in cities and towns come from the Provincial Department of Human Resources and Social Security. The data of medical insurance and maternity insurance come from the provincial medical insurance bureau; The data of urban and rural subsistence allowances, social welfare and community services come from the Provincial Civil Affairs Department; The data of water conservancy construction comes from the Provincial Water Resources Department; The data of aquatic product output and high-standard farmland construction come from the Provincial Department of Agriculture and Rural Affairs. Urban construction data comes from the Provincial Department of Housing and Urban-Rural Development; The data of nature reserves, geological parks and afforestation come from the Provincial Forestry Bureau. Surface water quality and air quality data come from the Provincial Department of Ecology and Environment; Safety production data comes from the provincial emergency management department; Other data come from the Provincial Bureau of Statistics and the Hunan Investigation Corps of the National Bureau of Statistics.

　　CCTV News:In Chongqing, meat consumption will increase as the temperature drops in winter. Coupled with the traditional festivals of New Year’s Day and Spring Festival, local residents have the traditional custom of curing bacon and filling sausages, which drives the rapid growth of pork consumption. In order to ensure the supply of the New Year’s Day holiday market, Chongqing has taken a number of measures to increase material input and stabilize the pork market price.

　　In the largest pig breeding base in Bishan, Chongqing, the reporter learned that although the daily slaughter of pigs reached more than 2,000, up 20% from the previous month, the price of pigs remained at 1 kg of 13 yuan, and the price remained basically unchanged compared with last month.

　　At the same time, the local government also actively guides large wholesale markets, supermarkets and farmers’ markets, organizes substitute products such as poultry meat, beef and mutton, rabbit meat and fish, increases market supply, makes up for the demand gap in the pork market, and relieves the supply pressure in the pork market. In order to ensure the rapid passage of transport vehicles for pork products, a "green passage" for transport vehicles has been opened up.

　　In order to thoroughly implement the decision-making arrangements of the CPC Central Committee and the State Council, conscientiously implement the notice requirements of the General Office of the Beijing Municipal Government on Several Measures to Continue to Increase the Assistance of Small and Medium-sized Enterprises and Accelerate the Recovery and Development of Difficult Enterprises (No.14 [2022] of Beijing Municipal Government), make overall plans for epidemic prevention and control and economic and social development, effectively reduce the impact of epidemic prevention and control on the production and operation of small and medium-sized enterprises in our region, and actively help difficult enterprises in the service sector to tide over difficulties and resume development, the implementation guidelines are specially formulated and issued.

　　First, reduce the burden on small and medium-sized enterprises

　　(a) the implementation of value-added tax refund at the end of the period.

　　1. Extend the policy scope of full monthly refund of incremental VAT tax allowance for advanced manufacturing industries to qualified small and micro enterprises (including individual industrial and commercial households). The stock tax allowance for qualified micro enterprises will be refunded in full from April 2022, and the stock tax allowance for qualified small enterprises will be refunded in full from May 2022, and the incremental tax allowance will be refunded in full from April 1, 2022.

　　Responsible unit: District Taxation Bureau

　　Goods and services tax section

　　Tel: 69649088

　　2. Intensify the policy of tax refund at the end of the VAT period in manufacturing, scientific research and technical services, software and information technology services, transportation, warehousing and postal services, and expand the scope of the policy of full monthly refund of incremental VAT in advanced manufacturing industries to qualified enterprises in manufacturing industries (including individual industrial and commercial households), and refund the stock of the enterprises in manufacturing industries at one time.

　　Responsible unit: District Taxation Bureau

　　Goods and services tax section

　　Tel: 69649088

　　(2) Implement the policy of tax reduction and fee reduction.

　　In 2022, the "six taxes and two fees" will be reduced for small-scale VAT taxpayers, small-scale low-profit enterprises and individual industrial and commercial households according to the 50% tax rate. Continue to implement the policy of adding and deducting value-added tax for production and life service industries. Small-scale taxpayers with monthly sales of less than 150,000 yuan are exempt from VAT. From April 1, 2022, the taxable sales income with 3% levy rate for small-scale VAT taxpayers will be exempted from VAT. For the part of small and meager profit enterprises whose annual taxable income exceeds 1 million yuan but not more than 3 million yuan, it will be included in the taxable income at a reduced rate of 25%, and the enterprise income tax will be paid at the rate of 20%. Increase the deduction ratio of R&D expenses of small and medium-sized science and technology enterprises to 100%. Increase the pre-tax deduction of equipment and appliances in small and medium-sized enterprises.

　　Responsible unit: District Taxation Bureau

　　Property and Behavior Tax Section

　　Social insurance premium and non-tax revenue section

　　Income tax section

　　Tel: 69620417, 69620257 and 69620075.

　　(three) reduction of housing rent for small and micro enterprises and individual industrial and commercial households in the service industry.

　　1. In 2022, small and micro enterprises and individual industrial and commercial households registered in Beijing or paying taxes in Beijing, which are state-owned houses in the leased area, will be exempted from rent for three months, among which, for renting state-owned houses in areas classified as high-risk areas in the epidemic, rent for six months will be exempted. State-owned, state-controlled and state-controlled enterprises should take the lead in putting them in place, and district-owned urban collective enterprises can refer to the implementation. For the state-owned houses with sublease, the relevant state-owned enterprises should ensure that the rent-free measures benefit the final tenant operators. Coordinate and promote central enterprises and municipal state-owned enterprises to implement rent reduction and exemption for small and micro enterprises and individual industrial and commercial households in our service industry.

　　Responsible unit: District SASAC

　　Performance evaluation center

　　Tel: 69680955

　　2. For the office space rent of qualified small and micro, start-up cultural enterprises, the maximum subsidy is not more than 300,000 yuan through the "rent pass" policy.

　　Responsible unit: District Cultural Promotion Center

　　Business Department

　　Tel: 69680072

　　3. For the owners of houses that have reduced or exempted the rent, if they are in line with the current policies of reducing or exempting the property tax and urban land use tax, they shall be reduced or exempted according to law.

　　Responsible unit: District Taxation Bureau

　　Property and Behavior Tax Section

　　Tel: 69620417

　　(D) the implementation of phased social security preferential policies

　　Continue to implement the 1% unemployment insurance rate policy until April 30, 2023. For catering, retail, tourism, civil aviation, road and railway transport enterprises, the policy of holding over the old-age insurance, unemployment insurance and work-related injury insurance premium will be implemented in stages. Enterprises recognized by the competent authorities of the industry can apply for holding over the old-age insurance premium from April to June 2022 and the unemployment insurance and work-related injury insurance premium from April to October 2022, and the late payment fee will be exempted during the holding over period.

　　Responsible unit: District Human Resources and Social Security Bureau

　　Social security center registration zhengjiaoke

　　Tel: 89688024

　　(5) Reduce the cost of epidemic prevention and control in enterprises.

　　In 2022, regular nucleic acid testing will be conducted for employees in catering, retail, cruise taxis, take-away, express delivery industries and small and medium-sized enterprises engaged in business activities related to imported non-cold chain goods free of charge.

　　Responsible unit: District Bureau of Commerce

　　Convention and Exhibition Center (supermarket and express delivery)

　　Tel: 69645066

　　Responsible unit: District Market Supervision Bureau

　　Food circulation safety supervision and management section (small social catering, small food circulation (retail), take-away food delivery)

　　Tel: 89681246

　　Responsible unit: District Transportation Bureau

　　Bohai team (transportation industry)

　　Tel: 69647664

　　Second, increase financial support.

　　(six) improve the convenience of corporate financing services

　　1. Establish a mechanism for district-level financial institutions to serve the financing needs of enterprises, and set up an enterprise financing demand service hotline (61673037) to co-ordinate and guide the financing needs of docking enterprises such as banks, guarantee and investment institutions, and track the effectiveness of docking services in a ledger manner.

　　2. Promote government financing guarantee institutions to reduce the guarantee rate, and strive to reduce the bank loan financing guarantee rate newly applied by small and micro enterprises in the service industry that are greatly affected by the epidemic to 1% in 2022.

　　3. Compile and publish the 2022 edition of Huairou Financial Products Manual, coordinate financial institutions to do policy propaganda and answer questions, and facilitate enterprises to make good use of financial products.

　　Responsible unit: District Finance Office

　　Tel: 61673037

　　(7) Cultivate small and medium-sized enterprises with science and technology.

　　Issue science and technology innovation vouchers to qualified small and micro enterprises, and pay no more than 300,000 yuan in financial subsidies for enterprises to purchase standardized services such as analysis, testing and inspection based on scientific research facilities and instruments.

　　Responsible unit: District Science and Technology Commission

　　High-tech industry development center

　　Tel: 69697671

　　Third, strengthen assistance to industries with outstanding impact on the epidemic situation

　　(eight) the implementation of catering industry relief support measures.

　　1. Encourage social catering enterprises to provide old-age catering services for the elderly, and subsidize social catering enterprises identified as old-age catering points according to the same standards of old-age service institutions.

　　Responsible unit: District Civil Affairs Bureau

　　Pension service affairs center

　　Tel: 69631036

　　2. Support catering enterprises to build new chain-operated restaurants, and the amount of support shall not exceed 50% of the total approved investment in principle.

　　Responsible unit: District Bureau of Commerce

　　Business development management section

　　Tel: 69646108

　　(nine) the implementation of retail relief support measures.

　　Give no more than 5 million yuan of financial support to the renovation of the facade of the commercial main body, the renovation of the store, the purchase of equipment and the construction of related supporting facilities in traditional shopping malls and business districts (characteristic commercial streets). For convenience stores, pre-warehouses, pharmacies and other projects that meet the construction and upgrading standards of basic convenience commercial outlets in this area, financial support of not more than 50% of the actual investment amount approved by each input will be given.

　　Responsible unit: District Bureau of Commerce

　　Business development management section

　　Tel: 69646108

　　(ten) the implementation of tourism relief support measures.

　　1. Increase the implementation of the support policy for tourism service quality margin, and increase the proportion of temporary refund of tourism service quality margin for qualified travel agencies to 100%.

　　Responsible unit: District Culture and Tourism Bureau

　　Industry management section

　　Tel: 69622508

　　2. Encourage government agencies, enterprises and institutions to hand over the scheme formulation, organization and coordination of trade union activities and exhibition activities held in accordance with regulations to travel agencies, and strengthen the management of fund use.

　　Responsible unit: District Federation of Trade Unions

　　palace of culture

　　Tel: 69691984

　　(eleven) the implementation of road and railway transportation relief support measures.

　　1. In 2022, the branches of railway transport enterprises will be suspended from paying VAT in advance for one year, and the income from providing public transport services such as bus passenger transport, taxis, long-distance passenger transport and shuttle buses will be exempted from VAT.

　　Responsible unit: District Taxation Bureau

　　Goods and services tax section

　　Tel: 69649088

　　2. Support the cruise taxi fuel vehicle to be updated into a pure electric vehicle, and reward the cruise taxi fuel vehicle that expired and scrapped in that year to be updated into a pure electric vehicle.

　　Responsible unit: District Transportation Bureau

　　Bohai team

　　Tel: 69647664

　　(twelve) the implementation of cultural performance industry relief support measures.

　　1. In 2022, the construction fee for cultural undertakings belonging to the local income of this district will continue to be reduced by 50% of the amount payable by the payer.

　　Responsible unit: District Taxation Bureau

　　Social insurance premium and non-tax revenue section

　　Tel: 69620257

　　2. Give subsidies and rewards to demonstration bookstores, transformation and upgrading bookstores and "Sanjin" bookstores.

　　Responsible unit: Propaganda Department of District Committee

　　Social propaganda department

　　Tel: 69626627

　　Fourth, the implementation of safeguards

　　(XIII) Establish a supply chain coordination mechanism for a stable industrial chain.

　　1. Make every effort to get through the transportation blocking points and ensure the smooth transportation of people’s livelihood materials and important production materials.

　　Responsible unit: District Bureau of Commerce

　　Business development management section

　　Tel: 69646108

　　Responsible unit: District Transportation Bureau

　　Tanghekou inspection office

　　Tel: 89672039

　　2. During the epidemic period, it is necessary to strengthen the service of enterprise visits, timely understand and coordinate and solve the difficulties of enterprise production and operation, and strive to maintain the stability of enterprise industrial chain supply chain and production and operation.

　　Responsible unit: District Investment Promotion Center

　　Enterprise service section

　　Tel: 69692561

　　Responsible unit: District Development and Reform Commission

　　Business environment center

　　Tel: 69621985

　　(fourteen) the establishment of small and medium-sized enterprises to help implement the policy mechanism.

　　1. Establish the database of small and medium-sized enterprises in the whole region, strengthen the dynamic update and daily monitoring of the database of small and medium-sized enterprises, and do a good job in overall planning and improvement.

　　Responsible unit: District Bureau of Economy and Information Technology

　　Enterprise service center

　　Tel: 69624008

　　2. Conduct quarterly sampling surveys on the operating conditions of small and medium-sized enterprises to find out the needs of enterprises and the effect of policy implementation.

　　Responsible unit: District Statistics Bureau

　　Industry and special section

　　Tel: 69627065

　　3. All relevant departments shall formulate detailed implementation rules in a timely manner according to needs, do a good job in publicity and interpretation, and expand the awareness and coverage of policies. Regularly sort out and submit the implementation of various measures, find problems in time and study and solve them, and get through the "last mile" of policy landing.

　　The scope of service industries to which the above policies and measures are applicable can be identified according to the Classification of National Economic Industries (GB/T4754-2017) and the Notice of the National Bureau of Statistics on Amending the Provisions on the Three Industrial Divisions (2012) (Guo Tong Design Management Letter [2018] No.74); The scope of small and medium-sized enterprises and individual industrial and commercial households can be identified by querying the "National Enterprise Credit Information Publicity System-National Service Network for the Development of Individual and Private Economy", or according to the Notice on Printing and Distributing the Standard Provisions for the Classification of Small and Medium-sized Enterprises issued by the Ministry of Industry and Information Technology and other departments (No.300 [2011] of the Ministry of Industry and Information Technology) and the Notice on Printing and Distributing the Standard Provisions for the Classification of Financial Enterprises issued by the People’s Bank of China and other departments (Yinfa [2015] No.300)

[car home Suqian Preferential Promotion Channel] Recently, a round of big discounts was launched in Suqian market, with the highest discount range reaching 159,500 yuan, which reduced its minimum starting price to 305,200 yuan. This move has undoubtedly brought unprecedented opportunities for car buyers. If you are interested in BMW i4, you may wish to click "Check the car price" in the quotation form to get a higher discount.

The front design of BMW i4 adopts the iconic kidney-shaped air intake grille, and the interior of the grille adopts a closed design, which highlights its electric identity. The overall style is mainly streamlined and dynamic, and the body lines are simple and smooth, creating a modern and dynamic appearance. The design of the front and rear also highlights the unique style of the BMW family.

The body size of BMW i4 is 4785*1852*1455mm, the wheelbase is 2856mm, the front tread is 1601mm and the rear tread is 1630mm. Its side lines are smooth and dynamic, with 18-inch rims, which are 245/45 R18 in front of tyre size and 255/45 R18 in rear of tyre size, showing a unique sports style.

The interior style of BMW i4 combines luxury and technology to create a modern and elegant atmosphere. The steering wheel is made of leather, which supports manual adjustment up and down and back and forth, providing a comfortable grip and accurate operation experience. The center console is equipped with a 14.9-inch touch screen, which integrates multimedia system, navigation, telephone and air conditioning voice recognition control system, greatly facilitating the driver’s operation. In addition, the front seats are made of imitation leather, genuine leather or leather /Alcantara mixed material, which supports multi-directional adjustment and heating functions to ensure the comfort of riding. There are also two USB and Type-C interfaces in the front row and the rear row, and the wireless charging function of the front mobile phone, which provides convenient charging and connection requirements for passengers. The rear seats can be tilted in proportion, which increases the flexibility of luggage space.

The BMW i4 is equipped with an efficient motor with a maximum power of 210kW and a maximum torque of 400 Nm. This provides the driver with strong power output and smooth acceleration experience.

Regarding the evaluation of BMW i4, he thinks that the configuration parameters of I series are almost the same, while i4 stands out with its unique design and import status. He proudly said: "The big nostrils are not mediocre at first glance. People who drive out are guessing at 600,000. I am embarrassed."

Driven by the trend of new energy, China automobile industry presents two development paths: hybrid and pure electric. As the leader of smart travel in the whole scene, Deep Blue Auto constantly explores the third solution of the industry and innovates the charging speed of pure electric vehicles on the basis of vigorously developing pure electric technology, which has also become the underlying logic of Deep Blue Super Range Extender.

Deep Blue Super Range Extender is based on the pure electric platform with full forward design, adheres to the technical route of pure electric drive, innovatively introduces the Force intelligent range extender system, truly innovates the energy-saving solution of fuel vehicles into the energy supply solution of pure electric vehicles, and creates a full-scene green travel solution that is most suitable for China’s national conditions, which is more futuristic, more electric and free of energy supply anxiety.

Super Savings Deep Blue Super Extension is a natural piggy bank.

The deep blue super extended range technology benefited from the technical innovation of the Force super electric drive and the Force intelligent range extender, which solved the deep-seated contradiction between vehicle driving performance and low fuel consumption for the first time. These two technologies won the China Top Ten New Energy Power System Award last year and this year respectively.

The Force Super Electric Drive is the power source of the Super Range Extender. It deeply integrates multiple high-voltage systems of the whole vehicle, drives with rear wheels, and innovates technologies such as adaptive efficiency optimization of loading conditions and real-time dynamic prediction of temperature field. The maximum efficiency of the system exceeds 95% and the maximum power exceeds 190kW. Force intelligent range extender is the energy supply station of super range extender, equipped with special engine and generator for range extender, adopting deep Atkinson cycle with high compression ratio, and 1L oil can generate about 3.3 kWh of electricity, reaching the best level in the industry.

As of November 17th, the number of products delivered by Deep Blue S7 with extended life has exceeded 100. According to the statistics of vehicle usage data of users with deep blue super endurance and extended range, 90% of the urban mileage is pure electric, 80% of the whole mileage is pure electric, and there is no refueling. In the remaining 20% of the refueling mileage, the actual average fuel consumption of deep blue users is as low as 5.2L/100km. Based on this calculation, per 10,000 kilometers, the deep blue ultra-endurance extended-range vehicle can save up to 5,058 yuan on average compared with the fuel vehicle, and it can save up to 1,128 yuan on average. The more you drive, the more you save. Since the launch of deep blue products, the deep blue extended-range model has saved users more than 540 million yuan in use costs and reduced carbon emissions by 60,600 tons. It not only saves the cost of vehicles, but also contributes to the sustainable development of society.

Cool dark blue super extended range has the feeling of permanent electric vehicle.

Deep Blue Super relies on the pure electric platform EPA1 all-electric digital platform to realize pure electric drive and has natural rear-wheel drive characteristics, which can provide smooth power, linear output and smooth running regardless of whether the vehicle has electricity or not.

In the aspect of quietness, the Force intelligent range extender adopts NVH intelligent balance strategy, howling frequency conversion active control technology, low torsional vibration structure design in all working conditions, active noise control of low-speed motor, etc., and the sudden change of noise in the car during starting and stopping the range extender system is ≤1.3dB, and the steering wheel vibration is ≤ 0.04 g when starting in situ; The Force Super Electric Drive adopts NVH active control technology and low noise electromagnetic scheme design technology, and the average sound pressure level at one meter is ≤78dB. Empowered by leading technology, the Deep Blue Super Range Extender can realize non-inductive start and stealth operation, bringing users a quiet and comfortable driving experience under various working conditions.

In addition, the deep blue super range extender can also carry out intelligent energy management according to multiple factors such as battery capacity, driving habits and road conditions, intelligently analyze the road conditions ahead and user needs through local algorithms and cloud big data, and intelligently start and stop the range extender system to improve power, economy and comfort. In addition, the power generation strategy will be automatically adjusted according to environmental factors such as temperature and altitude. The deep blue super range extender also realizes full-scene adaptive energy management, so that the vehicle can still maintain sufficient power output and pure electric driving experience in various special environments.

The super cool experience of deep blue super eternal electric vehicle was highly recognized by China Academy of Engineering, the father of electric vehicles in Asia and Chen Qingquan, a figure who moved China in 2022, and was included in his authoritative book The Mystery of Electric Vehicles.

Super Safe Deep Blue Super Extended Range makes you feel safe at all times.

The survey shows that the biggest anxiety of fuel vehicle users entering the era of intelligent electric vehicles comes from the anxiety of refueling and mileage on the one hand, and the distrust of battery attenuation and safety on the other hand.

Deep blue super range extender adopts Admiralty battery, based on iBC digital battery housekeeper, and realizes 24-hour all-round battery monitoring through 2 types of digital pre-control management technology groups and 7 types of digital temperature control management technology groups. Among them, the battery pack adopts IP3X short-circuit protection design, and the protection level is five times higher than the national standard. The unique battery sentry mode can detect the battery status in real time through U/T inspection, which can ensure the battery safety regardless of the vehicle’s driving, charging and static state. Multi-dimensional system safety design based on intrinsic safety, passive safety and active safety ensures that the battery does not catch fire and effectively avoids thermal runaway.

In this regard, Zeng Yuqun, the chairman of Contemporary Amperex Technology Co., Limited, an industry authority, gave high praise and recognition, and said that he would continue to join hands with Shenlan Technology and global partners to build the safest car in the world and let safer new energy vehicles run all over the world.

In addition to the safety guarantee of its own battery, Deep Blue Automobile is the first owner to meet the requirements of Deep Blue Ultra-Extended Range Power System, and provides lifetime warranties such as Super Electric Drive of the Force, Intelligent Range Extender of the Force, Admiralty Battery, etc., to provide more reliable guarantee for users’ vehicle safety.

For drivers and passengers, the Deep Blue Super Range Extender also provides automatic emergency braking (AEB), lane departure warning (LDW), 540 transparent chassis and surrounding high-strength body, providing all-round active and passive intelligent safety protection. It is worth mentioning that the new version of C-NCAP five-star safety evaluation was obtained in the evaluation released by China Automotive Technology and Research Center on November 15th. Among them, pedestrian automatic braking, two-wheeled vehicle automatic braking and lane keeping ability all rank in the top 20%, which is at the top level in the industry. With the fortress-level intelligent care, the deep blue super range extender can ensure the safety of users even under complex road conditions and working conditions.

With the three characteristics of natural piggy bank, permanent sense of electric vehicle and sense of security at all times, the official delivery of deep blue products equipped with super extended range system exceeded 100,000 units, and even successfully completed the limit test with multiple road conditions, complex working conditions and continuous high intensity across 15 countries in Asia and Europe. It is reported that in order to accelerate the global layout of the new energy market, Deep Blue will go to sea this month and will be unveiled at the Thailand Auto Show next week.

In the future, with the continuous recognition of consumers and the market, more and more consumers will join the Deep Blue Super Extended Range Team to contribute new impetus to low-carbon life.