The price/performance ratio is getting higher and higher. It smells good.
Since 2002, Dr. Tao has collected all kinds of domestic vaccine products, coded and photographed them, and unconsciously built the China Vaccine Museum.
This vaccine museum is located in the vaccine science popularization base in Kangtai, Shenzhen. Crucially, Dr. Tao is still tirelessly collecting new vaccine products to contribute to this museum.
Vaccine Museum at No.18 Shutianpu Road, Shenzhen
Not long ago, Dr. Tao just collected the third domestic IPV from Kexing Bio. The first two paragraphs are from Institute of Medical Biology (Academia Sinica) and Beijing Beishengyan Biological Products Co., Ltd. (Beishengyan). In this way, with the import of IPV from Pasteur, there are four IPV models in China.
I accidentally compared the instructions of four IPV companies and made my first major discovery. However, we need to popularize the common sense of polio vaccine first.
The polioviruses used in two domestic IPV come from live oral vaccines. The vaccine virus in oral live vaccine is also called sabin strain virus, so domestic IPV is also called Sabin IPV(sIPV). The polio virus in Pasteur IPV comes from wild virus, also known as WIPV.
Before sIPV came out in China, the single inactivated polio vaccine was all wIPV. However, the use of wild viruses in wIPV production requires the highest biosafety level in vaccine workshops, and the possibility of polio epidemic caused by leakage into the environment cannot be ruled out.
IPV is a good thing, and China also wants to replace the oral live vaccine with major defects for all children (see:The way to avoid the devil’s lottery and vaccinate polio safely）。 However, China has a large population, and IPV is many times more expensive than oral live vaccine. If IPV can be localized, it will be much easier.
Just do it. Academia Sinica, which produces oral polio live vaccine (known as "sugar pill" vaccine), took the lead. In order to reduce the construction cost and biosafety risk, they found another way to directly inactivate the virus in the live vaccine to make IPV, and sIPV was born in the world. Beishengyan and Kexing Bio have reached the next level, and domestic sIPV imports wIPV three to one PK.
However, whether wIPV is better or sIPV is a difficult question to answer at first, but with the two IPvs used in China for 10 years, some data began to surface or be confirmed.
At first, Dr. Tao thought that although the virus sources were different, there was no substantial difference between them, and even they were winners and losers. But this time, after carefully reading the instructions of the three companies, I found a common phenomenon:The antibody levels of three sIPV in clinical trials are much higher than those of wIPV.I’m a little embarrassed that I didn’t notice this before.
See the table below for specific data. The third dose of basic immunity refers to one dose at 2, 3 and 4 months old, and the first dose of additional immunity refers to the fourth dose at 18 months old. Fourteen months after the third dose of basic immunization refers to the blood sampling test before the fourth dose.
For three types of poliovirus, the antibody levels of three domestic sIPV were higher than those of imported wIPV as control group at any time point, and the antibody level of type I virus was more obvious. The number of observers in these clinical trials is about 300 ~ 600, and the sample size is large enough to be an error.
Dr. Tao can say with certainty that the short-term immune effect of domestic sIPV is better than that of imported wIPV. Of course, the immune effect and protective effect are not the same thing. In fact, imported wIPV has been used outside China for more than half a century, and there is no evidence that its protective effect is unreliable, so there is no need to abandon wIPV.
This week, Dr. Tao saw that the Chinese Academy of Sciences published the 10-year observation results of sIPV and wIPV in eClinicalMedicine, a sub-journal of The Lancet, which was the final word.
10-year observation results https://t.cn/A6OENJOH
It can be seen that after 10 years, the antibody level of sIPV is also higher than that of wIPV. Inferred from this trend, the high probability will be the same after 20 years, at most, it will be flat, and it is impossible for the antibody level of sIPV to be lower than that of wIPV.
There is no doubt that sIPV’s immune effect is better than wIPV’s in both short and long term.
The above is the good news that Dr. Tao wants to share with you.
In order to prevent polio, diphtheria, pertussis, tetanus and Haemophilus influenzae (Hib) infection, every child should be vaccinated with three kinds of vaccines: polio vaccine, DTP vaccine and Hib vaccine.
There are many permutations and combinations of these three vaccines, and Dr. Tao once recommended using five vaccines directly. However, the cost performance of this scheme has dropped a lot, and the cost performance of [quadruple vaccine+domestic IPV] scheme is getting higher and higher because of the following two reasons:
First, four doses of polio vaccine are required, and the government can provide two doses of domestic IPV free of charge.
If you use pentavaccine, you can’t enjoy this free policy, because the price of pentavaccine includes imported IPV. Enjoy 2 doses of free domestic IPV, at least you can save 540 yuan. In 2023, the supply prices of five vaccines and four vaccines are 638 yuan and 368 yuan respectively, which is different from 270 yuan. Multiplying two doses is 540 yuan.
In the future, all 4 doses of polio vaccine will definitely be changed to 4 doses of free domestic IPV, and then 1080 yuan can be saved, which will be too fragrant.
Second, the five-vaccine is wIPV, which is not as fragrant as sIPV. The evidence is conclusive.
Of course, the five-vaccine also has an advantage at present, that is, it can be vaccinated at the age of 2 months, one month earlier than the four-vaccine, and protected earlier. Therefore, you can also choose five vaccines at the age of 2 months, and then choose all [four vaccines+domestic IPV].
"We must strengthen the leading function of high-end industries, adhere to the strategic positioning of modern service industry as the mainstay and advanced manufacturing industry as the support, and strive to master the core links of the industrial chain and occupy the high-end position of the value chain."
"Grasp the transformation and upgrading of traditional industries on the one hand, and the development and growth of strategic emerging industries on the other, promote the accelerated development of manufacturing industry to digitalization, networking and intelligence, and improve the stability and modernization level of industrial chain supply chain."
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The security and stability of industrial chain supply chain is the basis of building a new development pattern. Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has been concerned about the safety and stability of the industrial chain supply chain. When he visited various places, he repeatedly made important instructions and put forward clear requirements, which pointed out the way forward for the vast number of enterprises to strive for high-quality development.
The entity is stable and the economy is stable. Turning over China’s economic map, from the three northeastern provinces as old industrial bases to the Pearl River Delta at the forefront of reform and opening up, from the equipment manufacturing that breeds great powers and heavy weapons to the emerging industries that are bubbling with vitality in generate, in the past ten years, the vast number of entrepreneurs have kept in mind the earnest entrustment of the General Secretary, strengthened their chains and bones, and made digital transformation for development, which has strongly supported China’s economy to be stable and far-reaching.
"We must strengthen the independent research and development of key core technologies and key components, realize technological self-reliance and self-improvement, and become a stronger and bigger national brand."
The first domestic full-face, large-slope inclined shaft boring machine applied to Luoning Pumped Storage Power Station passed the acceptance test successfully. The large-caliber EPB shield machine exported to Israel is being dismantled and shipped … Entering the shield assembly workshop of China Railway Engineering Equipment Group Co., Ltd., all the equipment is at full capacity, and many production lines are busy.
On May 10th, 2014, General Secretary of Supreme Leader inspected the shield assembly workshop of China Railway Engineering Equipment Group Co., Ltd., and affirmed the independent innovation of on-site scientific and technical personnel and workers to overcome scientific research problems and break through the technical barriers of shield machine system integration. The general secretary pointed out: "The equipment manufacturing industry is the backbone of a country’s manufacturing industry. At present, there are still many shortcomings in China’s equipment manufacturing industry. It is necessary to increase investment, strengthen research and development, accelerate development, strive to occupy the commanding heights of the world, and control the right to speak technology, so as to make China a modern equipment manufacturing country."
Bearing in mind the entrustment of the General Secretary, China Railway Equipment has established a major special research institute in conjunction with more than 500 upstream and downstream enterprises, and has successively broken through many key technologies such as large displacement pumps and main drive seals, and completed the application on the construction site.
Overcome the technological "fortress" and let enterprises reshape their development advantages. "In the first half of this year, the amount of new contracts signed by the company rose against the trend, with a year-on-year increase of 58%. Up to now, the cumulative order has exceeded 1,400 units and exported to more than 30 countries and regions. " Zhao Hua, Party Secretary and Chairman of China Railway Equipment, firmly said, "We will implement the important instructions of the General Secretary and strive to seize the commanding heights of the world roadheader technology."
As an important pillar industry of the national economy, the automobile industry has always been the main position to achieve technical self-reliance.
On July 23, 2020, General Secretary of the Supreme Leader learned about the research and development of new technologies and inspected the latest vehicle products in the vehicle hardware testing laboratory and enterprise exhibition hall of FAW Group R&D Institute. The general secretary stressed: "To promote the high-quality development of China’s automobile manufacturing industry, we must strengthen the independent research and development of key core technologies and key components, realize technological self-reliance and self-reliance, and become a stronger and bigger national brand."
"The general secretary’s entrustment has made the technicians present feel surging, which has also inspired our confidence and determination to achieve technical self-reliance." Wang Sibo, senior director of the Institute of Motor and Electric Drive of New Energy Development Institute of China FAW R&D Institute, said that in the past two years, he led the team to break through the key technology of ultra-high performance permanent magnet synchronous electric drive system, and the developed 245 kW electric drive system was successfully mass-produced and loaded, reaching the international leading level.
"China FAW thoroughly implements the spirit of the important speech of the Supreme Leader General Secretary, strengthens core technological breakthroughs and independent innovation of key technologies, and is gradually breaking through a series of key technologies." Xu Liuping, Party Secretary and Chairman of China FAW, introduced that in the field of traditional fuel engines, China FAW has independently controlled the high-efficiency and energy-saving power platform for passenger cars with a displacement of 1.0 liters to 6.0 liters, with an engine thermal efficiency of over 39%; In the field of hybrid power, it has broken through six core technologies, such as ultra-high compression ratio Miller cycle and low pressure EGR (exhaust gas recirculation system). In the field of new energy, we have broken through nine key technologies such as high-power motor, high-energy density battery and thermal runaway warning, and are developing technologies such as solid-state battery and hydrogen fuel engine.
Keep in mind the entrustment and forge ahead. Since the 18th National Congress of the Communist Party of China, China has firmly implemented the strong industrial base project and the industrial base reconstruction project. A number of key basic products and materials such as rail transit and power equipment have basically met the domestic needs, and key parts such as hub bearings, gears and racks have achieved technical and scale applications. The gratifying progress in tackling key problems in the industrial chain in key areas has helped to further enhance the core competitiveness of the manufacturing industry.
"I hope that enterprises will make persistent efforts in scientific and technological innovation, bravely climb the peak, and take new and greater steps in supporting the development of advanced manufacturing industries."
To strengthen the real economy, we should not only focus on building a solid industrial foundation, but also accelerate the development of advantageous industries, promote the modernization of industrial chains, and create products and services with global competitiveness.
On June 22, 2017, General Secretary of the Supreme Leader pointed out during the inspection of Shanxi Gangke Carbon Materials Co., Ltd.: "The new material industry is a strategic and basic industry, and it is also a key area of high-tech competition. We must catch up and catch up."
Slim in size, but able to resist high winds and run at high speed on the ice … In February this year, at the Beijing Winter Olympics, snowmobiles and snowmobile helmets made of TG800 carbon fiber from Shanxi Steel Company were unveiled, and they attracted countless powders.
The density of this carbon fiber material is only 1/4 of that of steel, but its strength is 5-10 times that of steel. With many excellent properties, it is praised as "black gold" by the industry and widely used in high-tech fields such as aerospace.
"In 2017, the second phase of the high-performance carbon fiber production line with an annual output of 500 tons is still under construction. Now the third phase of the project with an annual output of 1,800 tons of high-end carbon fiber has been put into production, and the fourth phase of the advanced composite material production line has also been completed." Yang Han, then the chief engineer, said that now the enterprise can meet the demand of high-performance carbon fiber for major national projects and key projects.
"In the future, it is planned to invest in two new 2,000-ton production lines and a flexible test line. It is estimated that by the end of the 14 th Five-Year Plan, the annual output of 6,000 tons of high-end carbon fiber will be achieved." Chang Chunbao, secretary of the Party Committee and general manager of Shanxi Iron and Steel Company, is full of confidence in moving towards a world-class carbon fiber industrial base.
Accelerate the development of advantageous industries, and traditional industries are also promising.
On May 24th, 2014, at the Technical Center of Shanghai Automotive Group, General Secretary of the Supreme Leader visited the automobile modeling design, prototype trial production and new energy joint debugging test. The general secretary affirmed their innovative spirit of catching up with the forefront and stressed that "developing new energy vehicles is the only way for China to move from a big automobile country to a strong automobile country".
Recalling the affirmation of SAIC’s innovative spirit during the general secretary’s inspection, Wang Jian, executive director of electric drive business of SAIC Jieneng Automobile Technology Co., Ltd., was very excited. In the past eight years, the intelligent electric drive gearbox team of SAIC, led by him, braved the "hard bones" with domestic suppliers and gradually mastered all key technologies such as motors, inverters and motor control software. In the third quarter of next year, the third-generation plug-in hybrid gearbox with faster shifting, stronger power and lower fuel consumption will be loaded in batches.
"The important instructions of the Supreme Leader General Secretary have pointed out the direction for the development of China’s automobile industry." Chen Hong, secretary of the Party Committee and chairman of SAIC, said that SAIC has put forward the goals of electrification, intelligent networking, internationalization and sharing. During the "Thirteenth Five-Year Plan" period, it has invested nearly 60 billion yuan in research and development, creating "seven technical bases" such as pure electric exclusive systematization platform, electromechanical integrated vehicle architecture and hydrogen energy exclusive architecture. During the "14th Five-Year Plan" period, SAIC will invest 300 billion yuan in the fields of new energy and intelligent networking, focusing on cutting-edge technologies such as skateboarding platform, integrated casting and solid-state batteries, and speeding up the solution of the "stuck neck" problem.
Looking to the upstream iron and steel industry, in the production workshop of China Baowu Taigang Stainless Steel Precision Strip Co., Ltd., coils of steel strip are finally turned into ultra-thin precision stainless steel foil after rolling, polishing, straightening and slitting. Groups of "hand-torn steel" with different specifications have gone to the world from here and entered the fields of aerospace, high-end electronics and new energy.
On May 12, 2020, when General Secretary of the Supreme Leader came to Taigang Stainless Steel Precision Strip Co., Ltd. for investigation and investigation, he picked up a piece of "hand-torn steel"-stainless steel foil with a thickness of only 0.02 mm, twisted it with his fingers and praised it: "Hundred steels have been made into soft fingers." The general secretary pointed out: "products and technology are the foundation for enterprises to settle down." I hope that enterprises will make persistent efforts in scientific and technological innovation, bravely climb the peak, and take new and greater steps in supporting the development of advanced manufacturing industries. "
"The words of the General Secretary are inspiring and firm in confidence!" Wang Tianxiang, secretary of the Party Committee and manager of Jingdai Company, said that over the past two years, the R&D team has experienced hundreds of tests and finally broke the thickness of "hand-torn steel" from 0.02 mm to 0.015 mm, and its performance and application have also extended to new fields. "Last year, production, sales and profits increased by two times compared with the previous year. In the first five months of this year, production and sales continued to be booming, and new breakthroughs are expected throughout the year."
Practice stronger unique skills and forge more industrial longboards. The output of more than 100 kinds of materials, such as advanced energy storage materials, photovoltaic materials and superhard materials, ranks first in the world, and 22 national manufacturing innovation centers, such as power batteries and additive manufacturing, have been laid out and built successively. Since the 18th National Congress of the Communist Party of China, a large number of outstanding enterprises have intensively cultivated in the fields of industrial advantages, making important contributions to supporting the construction of a manufacturing power.
"We must firmly promote industrial transformation and upgrading, strengthen independent innovation, develop high-end manufacturing and intelligent manufacturing, and promote China’s manufacturing industry and real economy."
For the industrial transformation and upgrading, the Supreme Leader General Secretary Nianzi is here and always pays close attention to it.
On September 17, 2019, General Secretary of the Supreme Leader stressed during his inspection of Zhengzhou Coal Mining Machinery Group Co., Ltd.: "We must firmly promote industrial transformation and upgrading, strengthen independent innovation, develop high-end manufacturing and intelligent manufacturing, and make China’s manufacturing industry and real economy."
Set a new world record In August, 2021, the prototype of 10-meter super-high mining height two-column shield hydraulic support developed by Zheng Coal Machine successfully rolled off the production line, creating a new height of coal mine support equipment in the world.
"From 8.8 meters to 10 meters, we have built the hydraulic support with the highest mining height and the highest technical index in the world." Wang Yongqiang, deputy general manager and chief engineer of Zheng Coal Machinery, proudly said, "We have been on a par with the leading enterprises of international coal machinery!"
"In recent years, we have always kept in mind the general secretary’s entrustment and made progress towards high-end." Jiao Chengyao, Party Secretary and Chairman of Zhengmei Machinery, said that at present, the enterprise sales network covers all coal-producing areas in China, and international orders have increased year after year. From January to June this year, overseas sales increased by 469% year-on-year.
Accelerating the transformation and upgrading of traditional industries requires both hardware breakthroughs and software assistance.
On December 12, 2017, when General Secretary of the Supreme Leader visited Xugong Group Heavy Machinery Co., Ltd., he came to the crane chassis assembly workshop of the company to inspect the intelligent production line and watch the operation demonstration of the industrial Internet big data platform. The general secretary pointed out: "The equipment manufacturing industry is the backbone of the manufacturing industry. It is necessary to increase investment, strengthen research and development, accelerate development, strive to occupy the commanding heights of the world, and control the right to speak technology, so as to make China a big country in modern equipment manufacturing."
"We dare not slack off for a moment!" Wang Min, chairman of Xugong Machinery, said that Xugong Machinery conscientiously implemented the spirit of the important speech of the General Secretary. After 10 years of process accumulation and 2 years of R&D and manufacturing, it solved the problem of low intelligent welding rate of turntable structural parts in crane industry. "We can proudly report to the General Secretary that the world’s first intelligent crane production line was born in China!"
Nowadays, the structural workshop of Xugong Hoisting Machinery Division has been greatly changed. Instead of a group of workers wearing heavy welding clothes, a group of robots are used to carry out intelligent welding operations, with a daily output of 40 cranes. The industrial Internet big data platform watched by the General Secretary has also ushered in a new upgrade. Xu Gong Hanyun’s industrial Internet platform has successfully empowered more than 80 industries including equipment manufacturing, non-ferrous metals and construction machinery, with over 70,000 service enterprises.
To speed up the transformation and upgrading, we should make green a bright background of traditional industries.
On October 22, 2018, General Secretary of the Supreme Leader came to Gree Electric Co., Ltd. and had a cordial conversation with researchers in the State Key Laboratory of Energy Saving for Air Conditioning Equipment and System Operation. The general secretary pointed out: "advanced manufacturing is a key to the real economy, and economic development can’t be divorced from reality at any time."
"With the care of the General Secretary, we are more motivated." Dong Mingzhu, chairman of Gree Electric, said that more than 10,000 R&D personnel kept in mind the entrustment of the General Secretary, made efforts to break through key core technologies and promote green transformation.
In April, 2021, at the Global Refrigeration Technology Innovation Grand Prix, the "zero carbon source" air conditioning technology developed by the joint team of Gree Electric and Tsinghua University won the highest prize in more than 2,100 projects in 94 countries.
"With the adoption of’ zero carbon source’ air conditioning technology, carbon emissions are lower than those of traditional air conditioners by more than 80%, and green efforts have made enterprises glow with new vitality." Dong Mingzhu said that the photovoltaic (energy storage) air conditioning system independently developed by Gree Electric has settled in more than 30 countries and regions, and the operating income of the green energy sector in 2021 exceeded 2.9 billion yuan, a year-on-year increase of 63%.
"As the General Secretary left Gree Electric, we shouted,’ Please rest assured, General Secretary! We must redouble our efforts to make the world love Made in China!’ We will work hard and make new achievements! "Dong Mingzhu said.
To promote high-quality economic development, we must make the real economy, especially the manufacturing industry, better and stronger, and take improving the level of the whole industrial chain as the main direction. Striving for a new journey and building a new era, under the strong leadership of the CPC Central Committee with the Supreme Leader as the core, adhering to the guidance of Socialism with Chinese characteristics Thought of the Supreme Leader in the new era, vigorously promoting scientific and technological innovation, accelerating key core technology research, and constantly improving the modernization level of the industrial chain supply chain, we will certainly be able to create new advantages for future development and write a new chapter of high-quality development.
(Reporter Wang Zheng, Han Xin, Li Xinping, He Linping, Zhu Peixian)
Realizing great rejuvenation is the greatest dream of the Chinese nation in modern times. In the report of the 19th National Congress of the Communist Party of China, General Secretary of the Supreme Leader profoundly pointed out that the initial intention and mission of the Communist Party of China (CPC) people is to seek happiness for the people of China and the rejuvenation of the Chinese nation. This initial intention and mission is the fundamental driving force to inspire the Communist Party of China (CPC) people to keep moving forward. The resounding slogan of "unremitting struggle for the Chinese dream of realizing the great rejuvenation of the Chinese nation" has played the strongest note of our time, brought together the common ideal of all Chinese sons and daughters, and led the goal direction of the country’s forward development.
The Chinese nation has a long history of more than 5,000 years, created a splendid Chinese civilization and made outstanding contributions to mankind. However, in modern times, our country has fallen behind in the closed door, sunk in complacency, and lost its way in the "great change that has never happened in a thousand years". Since the Opium War in 1840, China has been invaded and bullied by foreign powers. The country is poor and weak, and the people are in poverty. Countless people with lofty ideals shed their heads and blood to explore the road to saving the country. From the Taiping Heavenly Kingdom to the Westernization Movement, from constitutional monarchy to democratic revolution, they tried again and again and failed. The Chinese nation is still struggling in the dark. It was not until the October Revolution that a cannon shot sent us Marxism–Leninism and the Communist Party of China (CPC) took over the baton of saving the nation from national subjugation and strengthening the country that the great rejuvenation of the Chinese nation was dawned. After 28 years of bloody fighting, the Communist Party of China (CPC) overthrew the "three mountains" and established the People’s Republic of China (PRC), which made the people of China truly "stand up"; After 29 years of hard exploration, we found the road to Socialism with Chinese characteristics that conforms to the national conditions, started the great cause of reform and opening up, and gradually made the people of China "rich"; Since the 18th National Congress of the Communist Party of China, Socialism with Chinese characteristics has made great achievements in its career development at a new starting point, China’s comprehensive national strength and international influence have been significantly improved, and our country has really embarked on the road of "strengthening". China’s strength has changed,Become the second largest economy in the world, contributing 16% of the global economic aggregate; China’s role has changed, becoming an important participant and builder of the international system and increasingly moving towards the center of the world stage; China’s responsibility has changed, and it has become an important member of global governance, contributing China wisdom and China plan to "build a community of human destiny".
"It’s as true as iron that the Xiongguan is full of roads" and "the right path in the world is vicissitudes". Under the leadership of the Communist Party of China (CPC), the great rejuvenation of the Chinese nation has shown bright prospects. We are closer to the goal of the great rejuvenation of the Chinese nation than at any time in history, and we are more confident and capable of achieving this goal than at any time in history.
Why can the Communist Party of China (CPC) lead China to great rejuvenation? Because she has a strong leadership core. The Communist Party of China (CPC) is a ruling party with more than 89 million party member and 4.5 million grass-roots party organizations, leading more than 1.3 billion people in China to carry out modernization. Without centralized and unified leadership and a strong leadership core, it will be difficult to accomplish the arduous tasks entrusted by history. Looking back on the history of the party, the core of our party came into being at a major historical juncture, which is the choice of history and the choice of the times. Since the 18th National Congress of the Communist Party of China, the General Secretary of the Supreme Leader has raised the flag and planned the layout of articles, which has promoted the country’s economic and social development to make new achievements and led the cause of Socialism with Chinese characteristics to enter a new stage of development. "The achievements in the past five years are all-round and groundbreaking, and the changes in the past five years are deep-seated and fundamental." Practice has fully proved that with the strong leadership of the CPC Central Committee with the Supreme Leader as the core, we will have strong support for carrying out great struggles, building great projects, advancing great undertakings and realizing great dreams, and the Chinese nation will certainly be able to move towards great rejuvenation.
Why can the Communist Party of China (CPC) lead China to great rejuvenation? Because she is armed with scientific theories. One hundred years ago, under the guidance of Marxism–Leninism, the Russian October Revolution was successful and the first socialist country in the world was established. In the past 96 years, the Communist Party of China (CPC) has combined Marxism-Leninism with China’s national conditions, constantly innovated his views and sublimated his understanding in the practice of revolution, construction and reform and opening up, and finally formed the Socialism with Chinese characteristics Theory system, which provided a strong theoretical guidance for the country’s development and progress. Since the 18th National Congress of the Communist Party of China, General Secretary of the Supreme Leader has grasped the characteristics of China’s development stages and the changes of major social contradictions, deepened his understanding of various laws, and formed Socialism with Chinese characteristics Thought of the Supreme Leader in the new era. This is the latest achievement of Marxism in China, and it has realized that the Party’s guiding ideology keeps pace with the times once again. With the guidance of scientific theory, it will certainly give great impetus to the Communist Party of China (CPC)’s leading the people to realize the great rejuvenation of the Chinese nation.
Why can the Communist Party of China (CPC) lead China to great rejuvenation? Because she has the vitality of reform and innovation. "if you are new, you will be new, and you will be new." In the ever-changing international environment, the most fundamental thing is to make bold progress, meet challenges and realize the great rejuvenation of the Chinese nation by reform and innovation. The Communist Party of China (CPC) is a Marxist political party that is brave in exploration and practice, pioneering and innovating. Since its birth, it has undertaken the glorious mission of opening the way for national liberation and national development. Looking forward to the future, with the continuous deepening of comprehensive reform, Socialism with Chinese characteristics’s system will be more perfect, the national governance system and governance capacity will be modernized, Socialism with Chinese characteristics’s superiority will be more prominent, and the road to the great rejuvenation of the Chinese nation will surely become wider and wider.
Why can the Communist Party of China (CPC) lead China to great rejuvenation? Because she has the courage and ability of self-purification and self-revolution. It is the Communist Party of China (CPC)’s most distinctive character and greatest advantage to be brave in self-revolution and strictly manage the Party. As early as the Ruijin period, Chairman Mao profoundly pointed out that if corruption is not eliminated, the Soviet flag will not be played, and communist party will lose its prestige and popular support! Fighting corruption is the bounden duty of communist party people, and no one can stop it! It is this spirit of communist party people that has won the heartfelt support of the people and laid a solid foundation for the victory of the China revolution. Since the 18th National Congress of the Communist Party of China, facing the grim situation of the anti-corruption struggle, General Secretary of the Supreme Leader has promoted the comprehensive and strict administration of the Party from the height of the future and destiny of the Party and the country, and unswervingly "fighting tigers", "catching flies" and "hunting foxes", which has made the party’s work style and political style look brand-new and formed an overwhelming anti-corruption situation, providing a strong guarantee for realizing the great rejuvenation of the Chinese nation.
Why can the Communist Party of China (CPC) lead China to great rejuvenation? Because she has high-quality leading cadres and leading collectives. The Communist Party of China (CPC)’s efficient execution comes from high-quality leading collectives and leading cadres. Chairman Mao said: "After the political line is determined, cadres are the decisive factors". Historical experience tells us that the key to China’s success lies in the Party and people. Build a large contingent of high-quality cadres. This is an important task entrusted to the Communist Party of China (CPC) by history and an inevitable requirement brought about by profound changes in the world, national conditions and party conditions. Facing the complicated situation of international struggle and the new environment of domestic reform and opening up, facing new opportunities and challenges, the key to building a well-off society and building Socialism with Chinese characteristics in an all-round way lies in cadres, and the success or failure also lies in cadres. Leading cadres at all levels, as the backbone of the cause of the party and the country, their qualities, especially their ideological, political and moral qualities, are linked with the party’s cohesive force and combat effectiveness, with the people’s hearts, and with the success or failure of the rise and fall. Whether the Communist Party of China (CPC) can lead the people of all ethnic groups to seize favorable opportunities, overcome difficulties and challenges and realize the great rejuvenation of the Chinese nation depends on the quality and ability of leading bodies and cadres at all levels, and the key lies in how to turn organizational advantages and talent advantages into development advantages.
After a hundred years of struggle, the Communist Party of China (CPC) is worthy of the glorious mission of the national vanguard. History and reality have fully proved that only the Communist Party of China (CPC) can save China and develop China, and only the Communist Party of China (CPC) can shoulder the glorious mission of leading the great rejuvenation of the Chinese nation. (Dayan)
[Pacific Auto] In 2023, the brand-new domestic (|) long version and i5 pure electric version were officially unveiled. The new car adopted a brand-new design language, the appearance and interior were greatly improved compared with the current models, the body size was further strengthened, the power was also improved, and the comprehensive strength rose to a new dimension. It is understood that the new car is expected to be officially listed during the year or early 2024.
The pictures show BMW 5 Series and BMW i5 respectively, the same below.
In terms of appearance, the new car continues the design of overseas models as a whole, and the style is relatively conservative. The front face does not adopt the longitudinal kidney grille of the 4 series, nor does it adopt the design of the "squint" split headlights of the 7 series. Instead, based on the current model, the headlight group and the front surround have been adjusted, which is the right direction. After all, the appearance of the current 5 Series is very successful, and there is no need to make drastic adjustments.
On the side of the car body, the bright logo of "5" was designed at the corner of Hoxhorn, while the hidden door handle was designed, and a new style of wheel hub was replaced. The wheel hub size was available in 19 inches and 20 inches, which greatly improved the recognition and advanced feeling of the new car.
In terms of dimensions, the new 5-Series fuel version is the same as the pure electric version, with the length, width and height of 5175/1900/1520mm and the wheelbase of 3105mm respectively. Compared with the current model, the body length is increased by 69mm, 22mm and 20mm, and the wheelbase is unchanged.
The tail of the new car has changed obviously, and the shape of the taillight group has been redesigned, with similar style and high sense. At the same time, the rear surrounding shape is more prominent, showing a strong sense of movement.
As for the interior, the brand-new domestic BMW 5 Series adopts the latest generation of family-style design language, which is familiar with the design style of BMW 7 Series /i7. It is equipped with a 12.3-inch LCD instrument+a 14.9-inch touch screen to form a joint screen design, built-in iDrive 8.5 car system, and the air-conditioning outlet adopts a hidden layout, and the physical buttons in the original air-conditioning area are greatly reduced to touch operation, plus it is equipped with an encircling interactive light strip, which is both scientific and luxurious.
In addition, in order to meet the riding needs of Chinese people, the rear seat of the new domestic BMW 5 Series has been upgraded. The rear seat of the new car has not only been lengthened and thickened, but also a comfortable soft pillow has been customized for the front seat for the first time, and the exclusive logo of the word "five" is printed on the backrest of the front seat, further strengthening the special identity of China.
At the same time, the suspended giant screen launched by the BMW 7 Series will also become the exclusive option of the domestic long-wheelbase version of the 5 Series, with the characteristics of 8K, 31-inch and real-time interconnection. This configuration is not carried in the overseas version of the 5 Series. It can be seen that in order to please China users, BMW has specially equipped the configuration that meets the needs of Chinese people, which will also redefine the luxury.
In terms of power, according to the application information, the new BMW 525Li is equipped with a low weight of 2.0T, 156kW (212hp) and a top speed of 225km/h; The new BMW 530Li is equipped with a high-power 2.0T engine with a maximum power of 211kW (287HP) and a top speed of 250km/h.. The transmission system is matched with an 8-speed automatic manual transmission.
As for the (|) eDrive 35L model, it is equipped with a motor with a maximum power of 250 kW (340 HP) and a top speed of 190km/h, which is consistent with the eDrive 40L model. The battery life information is unknown at present. For reference, BMW i3 eDrive 40L is equipped with a 79.05 kWh battery pack, and the battery life under CLTC condition is 592km.
In addition, it is worth mentioning that, according to the official introduction of BMW, in terms of driving control and chassis, in order to better balance sportiness and long-distance comfort, the new BMW 5 Series has increased front and rear axles, nearly 50:50 axle load distribution ratio, intelligent structure and enhanced connection stiffness between the body and chassis.
The picture shows the current BMW 5 Series.
In terms of price, as a reference, the price range of the current domestic BMW 5 Series is 43.65-56.25 million, the terminal market discount is more than 80,000 yuan, and the entry-level model is less than 400,000 yuan, which is extremely cost-effective. The new BMW 5 Series has been upgraded in many aspects. It is expected that the price will be adjusted, and there will not be many discounts in the short term after listing. If you want to pursue cost performance and are not too interested in the design of the new BMW 5 Series, it may be a better choice to bargain-hunting the cash model now. (Text: Pacific Auto Wu Qi)
On April 6, Zhao Liying’s studio finally released the long-awaited "Yingye Notes" from fans. Zhao Liying appeared in a pink sweater, hair shawl, and delicate makeup. She greeted fans generously with a bright smile: "Long time no see, I miss you very much." Zhao Liying also revealed her previous life in isolation at home, saying that when she stayed at home, she would watch movies to make up for the epidemic, or make some food.
Zhao Liying said that while watching movies and chasing dramas at home, she also has to cook and cook, and of course she has to pay attention to the epidemic, which can be said to be full of positive energy. Many friends tease Zhao Liying, who is really enviable, lives leisurely, has a loving husband and a cute baby.
Zhao Liying’s condition was really good, her skin was still fair and tight, and she could not see that she had given birth to a baby at all, especially with her enviable baby face and pink sweater, she looked like an eighteen-year-old girl! It seemed that she and Feng Shaofeng were very happy after marriage! Look at this puffy face, so tender that you can pinch out water!
Since Zhao Liying was promoted to mother, her makeup hair has always been mature and atmospheric. If today’s curly hair is replaced by pure long straight hair, the taste will be different. It can be seen that Yingbao’s breakthrough and change, although the makeup is mature and gentle, Yingbao’s private clothes are still full of girlish heart.
Zhao Liying is now 32 years old, and she has given birth to a child. It is reasonable to say that her condition is going downhill, but I did not expect that her appearance and figure have not changed, but have become more youthful, which makes people’s eyes shine. Before, many people also said that Zhao Liying had a round face that was not good-looking, but now she can control a variety of shapes with a round face, which has to be admired.
Zhao Liying is still in Hengdian and has been involved in the filming of "Youfei". After resting at home for nearly a month, she can finally work now. This is the best news for Zhao Liying, the desperate third mother.
Because "You Fei" is the first play she made a comeback after giving birth, she personally values it very much, and the male lead is Wang Yibo, who is now the most talked about, I believe that after the broadcast, it will definitely be followed and sought after by everyone. Zhao Liying is Muse in the eyes of everyone, but when she returns home, she is a virtuous wife and a gentle mother. Looking forward to the new drama!
1905 movie network feature The X-Men were not to be outdone. In the new series, there were not only more than 20 mutants, but also young and old versions of the same character. Among them, Professor X and "Mystique Girl" even had a super cute toddler version.
This time, Chinese actor Fan Bingbing played the newly added mutant "Blink". Although her appearance was highly praised and she also claimed to be "the best Chinese element", in fact, Fan Bingbing’s scenes were not many, and most of them were in combat mode. The whole film only had one line.
Uncle Wolf is fully naked
The Strongest in History
The collection of more than 20 mutants is the strongest in history, and Uncle Wolf is fully naked
In "X-Men: Reverse the Future", mutated humans were in a life-and-death situation, and mutated humans from all over the world participated in this rescue movement. Audiences could see all kinds of bizarre "superpowers" of mutated humans, which was very enjoyable. In addition to the main characters, there were also more than 20 mutated humans in "X-Men", including Storm, Phantom Cat, Quicksilver, Iceman, Flicker, Gunnyman, Bishop, Journey, Sunspot, Ravager, and Toad, which could be called the "Strongest Mutant Alliance".
Among these mutants, Wolverine and "Mystique" have the heaviest scenes. In order to reverse the fate of the mutants, Wolverine returned to 1973 and became a communicator between the two time and space. The 46-year-old "Wolf Uncle" Hugh Jackman dedicated himself to the bed scene in the film. He showed his muscles naked, only did dark light treatment in important parts, was almost naked, and his superb figure was also very exciting. And Jennifer Lawrence’s "Mystique" is the point person of the film. She has to choose between the values of Professor X and Magneto. Whether she can let go of her hatred will determine whether the mutants can get out of the endless cycle of "revenge".
Since the story takes time travel as a clue, it is very rare to gather the young and old versions of Professor X, Magneto and the Beast in the film. But this time, the young version of Professor X who charmed everyone in the prequel has long hair, a beard, and a rather decadent appearance. In addition, the audience can also see the original and future versions of the villain "Sentinel". The former is still unconscious and is a robot for human use, so the shape does not get rid of the essence of the machine, with light purple and metallic white as the main color scheme. The latter can fight independently, and the combat power is so strong that the mutants cannot resist it. The shape is relatively close to humans, mainly black.
From the perspective of the viewing effect, the most outstanding character in the film is the new "Quicksilver", which has the same fast-moving skills as the Korean "Professor Du". When the shape was first exposed, "Quicksilver" was once ridiculed by fans as "Killing Matt". But from the plot point of view, the eccentric shape is very much in line with his character setting that does not play cards according to the rules. "Quicksilver" also complained to Wolverine in the film, molesting Magneto, making them unable to fight back, which is quite witty and won bursts of laughter from the audience. He performed very well in the scene where he rescued Magneto, which became a highlight of the whole film.
Fan Bingbing
Chinese elements
The Great Wall became the last base of the X-Men Fan Bingbing with only one line
Many people still remember the simple and crude Chinese elements, and this time, "X-Men: Reverse the Future" does a relatively good job. At the beginning of the film, the future mutants are hunted down and retreated to the Great Wall of China, so the future part of the plot is basically unfolded on the Great Wall made by 3D special effects. In order to create a sense of doom, the color of the picture is very gray, and the Great Wall is deserted, like the last ruins on earth, which looks tragic and depressing. In the special effects fight scene, the super-power scene of the Iceman and "Storm" is very spectacular, but the future version of "Sentinel" has super destructive power, and the scene of the confrontation between the two sides has excellent visual effects. When he returned to the scene of the past, the picture of the movie returned to clarity, the first generation of "Sentinels" appeared neatly, and the scene of the entire stadium being uprooted was quite shocking.
Fan Bingbing, who claims to be "the best Chinese element", plays "Flicker" in the original comic book, a mutant with space transmission superpowers. At the beginning of the character’s appearance, many fans of the original book recognized its reduction. From the film’s perspective, Bingbing’s more attentive performance and the help of special effects have indeed given life to this debut character. However, Fan Bingbing does not have many scenes in the film, and most of them are in combat mode, so there are not many lines, only one sentence, a total of only three English words.
In addition, "X-Men: Reverse the Future" also has an Easter egg hidden at the end of the film. The Egyptian pyramids appear in the Easter egg, as well as four looming horsemen. It seems that after the Chinese elements, the next "X-Men" story may be set in Egypt.
On August 16, Chen Edison [Weibo] posted a photo of his daughter Alaia on his social account, with the caption "7:20 am, with my daughter and Doraemon". In the photo, Alaia’s hairstyle is very messy, her hair is casually blocked in front of her eyes, and her expression is cold and uninhibited, very stylish, next to Doraemon toys.
When netizens saw this, they left messages one after another, "It has the same taste as dad and mom." "Sure enough, with dad, the painting style is different" "messy and beautiful".
Today, BYD Tang family launched a number of new cars, including Tang EV Glory Edition, Tang DM-p Glory Edition and 2024 Tang DM-p Ares Edition, with a starting price of 219,800 yuan. The BYD Tang family listed more cars.
Tang EV Glory Edition and Tang DM-p Glory Edition follow the design style of the champion version. The former adopts "EV Dragon Face" front face and closed grille, with a body size of 4900/1950/1725mm and a wheelbase of 2820mm. The latter adopts the "Dragon Face" design concept and hexagonal air intake grille, with a body size of 4870/1950/1725mm and a wheelbase of 2820mm.
The interior layout of the two models is the same, but the seat layout is slightly different: Tang EV Glory Edition offers 7 seats, Tang DM-p Glory Edition has 6 seats, and the rest models have 7 seats. Both of them are equipped with the advanced version of DiLink 100 intelligent cockpit, the central control panel has a resolution of 2.5K, and it is equipped with D100(6 nm) chip. The system UI has been newly designed, with dual desktop display functions of map and wallpaper, and supports 3D car control.
Tang EV Glory Edition offers two-wheel drive and four-wheel drive versions. The maximum power of the two-wheel drive model is 168 kW or 180 kW respectively, the peak torque is 350 Nm, and the cruising range of CLTC is 600 km or 730 km respectively. The four-wheel drive model has a comprehensive power of 380 kW, a peak torque of 700 Nm, and a cruising range of 635 km under CLTC conditions. The BYD Tang family listed more cars.
Tang DM-p Glory Edition is equipped with a plug-in hybrid system consisting of a 1.5T engine and front and rear dual motors. The maximum power of the engine is 102 kW and the peak torque is 231 Nm. The comprehensive power of the motor is 360 kW, the comprehensive torque is 675 Nm, and the pure electric cruising range is 215 km. Both models come standard with Yunqi -C intelligent damping body control system.
As a special edition model, Tang DM-p Ares Edition adopts silver sand black car paint, with blackened appearance kit, 21-inch black rim and 6-piston fixed pliers painted with golden armor and yellow. The main color of the interior is black, and it is made of suede and leather. It is also equipped with the DiLink 100 intelligent cockpit high-end version of the car system, retaining the 2+3+2 seat layout. Its power configuration is the same as that of Tang DM-p Glory Edition.
The Ministry of Industry and Information Technology released the economic operation of the software industry in the first quarter of 2022. In the first quarter, China’s software and information technology service industry (hereinafter referred to as "software industry") operated steadily, with double-digit growth in software business income, narrowing the decline in total profits and slowing down the growth rate of software business exports.
I. Overall operation
Software business revenue maintained steady growth.In the first quarter, China’s software business revenue was 2,006 billion yuan, up 11.6% year-on-year, and the growth rate was the same as that in January and February, which was 2.7 percentage points higher than the two-year average growth rate in the same period of 2020 and 2021.
Figure 1 Software business revenue growth
The decline in total profits narrowed.In the first quarter, the total profit of the software industry was 203.1 billion yuan, down 3.9% year-on-year, and the decline was 3.7 percentage points narrower than that in January-February.
Figure 2 Total profit growth of software industry
The export growth rate of software business slowed down.In the first quarter, the export of software business was US$ 11.6 billion, up 4.3% year-on-year, and the growth rate dropped by 2.8 percentage points compared with that in January and February. Among them, the export of outsourced services increased by 14.1% year on year.
Figure 3 Growth of Software Business Export
Second, the sub-field operation
Revenue growth of software products picked up.In the first quarter, the revenue of software products was 509.7 billion yuan, up 9.8% year-on-year, and the growth rate was 0.8 percentage point higher than that in January-February, accounting for 25.4% of the industry’s revenue. Among them, the income from industrial software products was 51.4 billion yuan, up 12.1% year-on-year; Basic software revenue increased by 9.5% year-on-year.
The growth rate of information technology service income is outstanding.In the first quarter, information technology service revenue was 1,310.2 billion yuan, up 13.7% year-on-year, 2.1 percentage points higher than the overall growth rate of the whole industry, accounting for 65.3% of the total revenue of the whole industry. Among them, cloud computing and big data services realized a total revenue of 205.2 billion yuan, a year-on-year increase of 10.4%, accounting for 15.7% of information technology service revenue; The revenue from integrated circuit design was 53.8 billion yuan, up 17.2% year-on-year; The technical service income of e-commerce platform was 191.6 billion yuan, up 19.7% year-on-year; The service revenue of industrial Internet platform increased by 17.4% year-on-year.
Revenue from information security products and services has accelerated.In the first quarter, the revenue from information security products and services was 33.8 billion yuan, up 12.9% year-on-year, and the growth rate was 1.5 percentage points higher than that in January and February.
The growth rate of embedded system software revenue dropped.In the first quarter, the revenue of embedded system software was 152.2 billion yuan, up 0.3% year-on-year, and the growth rate dropped by 7.5 percentage points compared with January-February.
Figure 4 Proportion of classified revenue of software industry in 2021 and the first quarter of 2022
Third, the operation by region
The income of the software industry in the eastern region has increased steadily, and the growth in the central and western regions is outstanding.In the first quarter, the revenue from software business in the eastern region was 1,656.5 billion yuan, up 10.7% year-on-year, and the growth rate dropped by 0.1 percentage point compared with that in January and February. The revenue from software business in the central region was 66.6 billion yuan, up 14.7% year-on-year, which was 3.1 percentage points higher than the overall growth rate of the whole industry. The revenue from software business in the western region was 247.2 billion yuan, up 18.2% year-on-year, 6.6 percentage points higher than the overall growth rate of the whole industry; The revenue from software business in Northeast China was 35.6 billion yuan, up 2.4% year-on-year, and the growth rate dropped by 4.4 percentage points compared with January-February. The software business income in the four regions accounted for 82.6%, 3.3%, 12.3% and 1.8% of the total national income respectively.
Figure 5 Revenue growth of software industry by region in the first quarter of 2022
The proportion of business income in major software provinces declined slightly.In the first quarter, among the top five provinces in terms of software revenue, the software revenues of Beijing, Guangdong, Jiangsu, Zhejiang and Shanghai were 439.5 billion yuan, 378.5 billion yuan, 280.6 billion yuan, 172.6 billion yuan and 164.8 billion yuan, respectively, increasing by 13.2%, 6.1%, 10.5%, 5.4% and 17.6%.
Figure 6 Growth of top ten provinces and cities in software business income in the first quarter of 2022
The revenue growth of software business in central cities has slowed down, and the total profit is still negative.In the first quarter, the software business income of 15 sub-provincial central cities nationwide was 1,039.7 billion yuan, up by 8.3% year-on-year, and the growth rate dropped by 0.7 percentage points compared with that of January-February, accounting for 51.8% of the national software business income, down by 1.6 percentage points compared with the same period last year. Among them, the growth rate of software business income in eight cities, including Ningbo, Jinan, Xiamen, Xi ‘an, Guangzhou, Dalian, Wuhan and Qingdao, exceeded the overall growth rate of the whole industry. The total profit was 108.7 billion yuan, down 11.9% year-on-year.
Figure 7 Growth of Software Business Revenue in Sub-provincial Central Cities
Sit and watch the bamboo turn into a lovely branch.
The third solar term in winter-heavy snow
Come as promised
from then on
The weather will get colder.
Snowstorms will become more frequent.
People began to get busy preparing for winter.
Data Map: The picture shows the snow scene in Guanshan, Pingliang, Gansu.
"Heavy snow" does not mean "heavy snow"
Heavy snow is the third solar term in winter, and entering the solar term of heavy snow also means the official start of the mid-winter season. Interestingly, the solar term of heavy snow is not equivalent to its literal meaning of "heavy snow". Compared with the light snow solar term, the heavy snow solar term is not necessarily an increase in snowfall, but an increase in the probability of snowfall or snow accumulation. When there is light snow, the snow melts with it; When it snows heavily, the snow accumulates with it, that is, the snow "sits still".
Is there snow in Shandong recently?
Cloudy and sunny weather will prevail in the next three days.
In the next three days, most areas in our province will be dominated by cloudy and sunny weather, and the temperature will slowly rise. On the 9 th, the highest temperature in southern Shandong and central Shandong will reach about 11 C, but the lowest temperature in some areas will still be below 0 C. It is necessary to keep warm in the morning and evening.
Forecast of major cities in the province in the next three days
7 th night to 8 th day
The weather in southern Shandong is cloudy and cloudy, while it is cloudy and sunny in other areas. The short-term southerly winds in the peninsula are 3 ~ 4, the southerly winds in Linyi and Rizhao are 2 ~ 3, and the southerly winds in other areas are 2 ~ 3.
The lowest temperature: about -3℃ in northwest Shandong, middle Shandong and inland peninsula, and about 0℃ in other areas.
Maximum temperature: around 8℃ in Dezhou and Binzhou, and around 10℃ in other areas.
8 th night to 9 th day
The weather in southern Shandong is cloudy and cloudy, while it is sunny and cloudy in other areas. In the peninsula, the north wind turns to the south wind 3 ~ 4, the south wind in Linyi and Rizhao is 3 ~ 4, and the north wind turns to the south wind 2 ~ 3 in other areas.
The lowest temperature: about -4℃ in northwest Shandong and inland peninsula, about 1℃ in southern Shandong and coastal areas, and about -1℃ in other areas.
Maximum temperature: about 11℃ in southern and central Shandong, and about 9℃ in other areas.
Weather trend forecast for the next 4 ~ 7 days
Next 4 ~ 7 days
Cloudy weather predominates in most areas of our province.
Affected by cold air on the 10th.
The province is dominated by the north wind.
The weather in Rizhao and Peninsula of Linyi is cloudy with light rain or sleet.
The weather in other areas is cloudy and sunny.
Please pay attention to the approaching forecast in time.
